This patent application is for a herbal topical composition to treat acne vulgaris. It contains an effective combination of chitosan nanoparticles and an alcoholic extract of Tinospora cordifolia. A skin cream is prepared from this combination along with pharmaceutical excipients. Testing showed this composition effectively inhibits Propionibacterium acnes in amounts needed to treat acne. The ratios of chitosan nanoparticles and Tinospora cordifolia extract providing this inhibition were determined.

1. (12) PATENT APPLICATION PUBLICATION (21) Application No. : 2556/MUM/2014
(19) INDIA
(22) Date of filing of Application :08/08/2014
(43) Publication Date : 22/08/2014
Journal No. - 34/2014
(54) Title of the invention : HERBAL TOPICAL COMPOSITION FOR TREATMENT OF ACNE
VULGARIS
(51) International classification
:A61k36/00,
a61k9/00
(31) Priority Document No :NA
(32) Priority Date :NA
(33) Name of priority country :NA
(86) International Application No
Filing Date
:NA
:NA
(87) International Publication No : NA
(61) Patent of Addition to Application
Number
Filing Date
:NA
:NA
(62) Divisional to Application Number
Filing Date
:NA
:NA
(71)Name of Applicant :
1)DR. RAJESH C. PATIL
Address of Applicant :BHAVAN"S COLLEGE,
ANDHERI WEST, MUMBAI 400 058 Maharashtra
India
(72)Name of Inventor :
1)DR. KAKOLI DASSHARMA (India)
2)DR. ARVIND SAMB KULKARNI (India)
3)DR. MADHURA DEEPAK MUKADAM
(India)
4)DR. RAJMAHAMMAD RASUL TAMBOLI
(India)
5)DR. VIDYA SUNIL TALE (India)
6)MR. BHUPENDRA LALIT MADAVI (India)
7)MR. SUDESH D. RATHOD (India)
8)DR. MANISHA KULKARNI (India)
(57) Abstract :
In one of the most important aspect of the invention topical composition of Chitosan nanoparticles and
Tinospora cordifolia as combination is provided for the treatment of Acne Vulgaris, the skin cream is
prepared from the combination of an effective amount of Chitosan nanoparticles, alcoholic extract of
Tinospora cordifolia along with pharmaceutically acceptable excipients; Further an effective amount for
the inhibition of propionibacterium acne is obtained; The ratio of the combination of an effective amount
of Chitosan nanoparticles, alcoholic extract of Tinospora cordifolia is also determined;
Number of Pages = 24