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Community mental health
Chetraj Pandit BPH,MPH
Lecture, YCHS, Kathmandu,
Nepal
2/16/2020 1Chetraj Pandit
Mental health in community
• Community services include:
• Psychiatric wards of general hospitals,
• local primary care medical services,
• day centers or,
• community mental health club houses centers, and
• self-help groups for mental health.
• The services may be provided by government organizations and
mental health professionals, including specialized teams providing
services across a geographical area, and may be provided by private
or charitable organizations.
2/16/2020 2Chetraj Pandit
• A community mental health program should :
• Provide mental health care in the community itself
• Focus services on the total community
• Focus on the preventive and promote services
• Provide continuing and comprehensiveness of services
• Provide indirect services like consultation, mental health
education etc.
2/16/2020 3Chetraj Pandit
Types of Mental Illness
Major illnesses are called psychoses (out of touch with reality). Major
illnesses are:
SCHIZOPHRENIA (Split Personality) – pt lives in a dream world of his
own.
MANIC DEPRESSIVE PSYCHOSES – symptoms vary from heights of
excitement to depths of depression.
PARANOIA – extreme suspicion & progressive tendency to regard the
whole world in a framework of delusions.
2/16/2020 4Chetraj Pandit
Types of Mental Illness
Minor illnesses are 2 groups:
NEUROSIS OR PSYCHONEUROSIS - pt is unable to react normally to
life situations. Peculiar symptoms may occurs e.g. morbid fears,
compulsions, obsessions.
PERSONALITY & CHARACTER DISORDERS – legacy of unfortunate child
hood experiences and perceptions.
2/16/2020 5Chetraj Pandit
Mental disorder
•A mental disorder, also called a mental
illness, psychological disorder or psychiatric
disorder, is mental or behavioral pattern
that causes either suffering or a poor ability
to function in ordinary life.
2/16/2020 6Chetraj Pandit
Behavior disorder
•Emotional and behavioral disorders (EBD) is a
broad category which is used commonly in
educational settings, to group a range of more
specific perceived difficulties of children and
adolescents.
2/16/2020 7Chetraj Pandit
82/16/2020 Chetraj Pandit
Introduction
• Many factors are responsible for the causation of mental illness. These
factors may predispose an individual to mental illness, precipitate or
perpetuate the mental illness.
2/16/2020 9Chetraj Pandit
Predisposing factors
• Predisposing factors exist in the individual. These factors determine
an individual susceptibility to mental illness. They interact with
precipitating factors resulting in mental illness. These predisposing
factors are:
Genetic makeup: is the study of heredity
Physical damage to the central nervous system
Adverse psychological influences
2/16/2020 10Chetraj Pandit
Precipitating factors (or exciting factors)
• These are events that occur shortly before the onset of a
disorder and appear to have induced it. Eg. death of
loved one.
2/16/2020 11Chetraj Pandit
• Physical Factors: These include infections, intoxications, endocrine,
circulatory, nutritional disturbances and trauma.
• Infections and Toxins: patients with hyperpyrexia, pneumonia, typhoid,
scarlet fever, influenza, septicemia and syphilis.
• Trauma: a fall from a height, forceps delivery or road traffic accident, a
result of rape, natural disaster or loses.
122/16/2020 Chetraj Pandit
Thus etiological factors of the mental illness can be grouped as
follow:
• Biological factors
• Physiological factors
• Psychological factors
• Social factors
2/16/2020 13Chetraj Pandit
Biological Factors include:
• Heredity
• Biochemical factors
• Brain damage
2/16/2020 14Chetraj Pandit
Heredity:
• What one inherits is not
the illness or its symptoms,
but a predisposition to the
illness, which is determined
by genes that we inherit directly. Studies have shown that three
fourths of mental defectives and one third of psychotic
individuals owe their condition mainly to unfavourable heredity.
2/16/2020 15Chetraj Pandit
Physiological Factors:
• puberty,
• menstruation,
• pregnancy,
• delivery,
• puerperium and
• climacteric.
• These periods are marked not only by physiological (endocrine) changes
but also by psychological issue that diminish the adaptive capacity of the
individual. Thus individual becomes more susceptible to mental illness
during this period.
2/16/2020 16Chetraj Pandit
172/16/2020 Chetraj Pandit
Introduction
• The clinical manifestations are the end products of various
forces of internal conflicts of the individual. The intensity and
persistence of symptoms will indicate manifestation of the
disease.
182/16/2020 Chetraj Pandit
Signs and Symptoms of Mental Illness
1. Alterations of personality and behaviour
2. Alteration in the level of consciousness
3. Alterations of Biological Functions
4. Disturbances in Mental Functions:
5. Changes in individual and Social Activities:
6. Somatic complaints:
7. Disturbances in motor behaviour:
192/16/2020 Chetraj Pandit
1. Alteration in the level of consciousness:
• may be in fully conscious, semiconscious, lethargic,
somnolence, stupor, and coma.
• Conscious: fully alert, aware of time, place and person.
• Semiconscious: forgetfulness of an events or a person for a
while, later remembers the situation.
202/16/2020 Chetraj Pandit
• Lethargy: aware of stimuli, dull senses, and slow responses.
• Somnolence: rarely awake, hardly aware of environmental
stimuli.
• Stupor: occasionally aware of environmental stimuli, forceful
stimuli needed to bring awareness.
• Coma: unconscious, variable response to stimuli,
incontinence of faeces and urine.
• Facial expression: dull, not interested.
212/16/2020 Chetraj Pandit
2. Disturbances in bodily functions
• Sleep
• Appetite and food intake
• Biological function
• Sexual desire and activity
222/16/2020 Chetraj Pandit
• Sleep:
• Disturbed sleep throughout the night, or
• no sleep at all, or
• difficulty in falling asleep, or
• waking up in the middle of night and failing to asleep again.
• lethargy and lack of freshness in the morning.
232/16/2020 Chetraj Pandit
• Appetite and food intake: Increased or decreased appetite,
weight loss or weight gain, nausea, vomiting.
• Biological function:
• Diarrhoea and constipation, increased micturation, bed
wetting.
• Persistent deviation in temperature, pulse and respiration,
headache, pain, fatigue.
242/16/2020 Chetraj Pandit
• Sexual desire and activity:
• Decreased interest in sex,
• premature ejaculation,
• impotence or lack of sexual satisfaction.
• In some condition there can be excessive sexual desire or
lack of social inhibitions.
252/16/2020 Chetraj Pandit
3. Disturbances in Mental Functions:
• Behaviour
• Speech
• Thought
• Emotions
• Perception
• Attention and concentration
• Memory
• Intelligence and judgement
• Insight:
262/16/2020 Chetraj Pandit
• Behavior:
• over activity, restlessness, irritability, may be abusive (for
trivial or no responses at all)
• dull, withdrawn and not respond to external and internal
cues.
• Sometimes the patient’s behaviour can be dangerous to self
or others.
272/16/2020 Chetraj Pandit
• Speech:
• talks excessively and unnecessarily or talks very little or
stays mute.
• talk becomes irrelevant and un-understandable (in
coherent).
282/16/2020 Chetraj Pandit
• Thought:
Patient expresses peculiar and wrong beliefs which other do
not share.
• Emotions:
• Patient may exhibit excessive emotions like excessive
happiness, anger, fear, or sadness.
• Sometimes emotions can be inappropriate to situations (laugh
to self or weep without any reason).
292/16/2020 Chetraj Pandit
• Perception:
The patient may perceive without any stimulus. There can be
misinterpretation of perception.
• Hallucinations (see things or hear sounds or feel objects which
do not exist or others do not see). -Auditory, visual.
302/16/2020 Chetraj Pandit
• Illusion (misperception of external stimuli)
• Delusions (false, unshakable belief which is firmly held on
inadequate grounds not affected by rational or logical
arrangements) are of examples.
312/16/2020 Chetraj Pandit
• Attention and concentration:
• decreased attention and concentration:
• he/she may get distracted easily, or
• have selective in attention.
• Memory: Patient may lose his memory and start forgetting
important matters.
322/16/2020 Chetraj Pandit
•Intelligence and judgement:
•Deteriorating in intelligence and judgement.
•loses reasoning skills and abilities (may not be able to
perform simple arithmetic or commits mistakes in
routine work).
• Insight: Insight may be absent or present
332/16/2020 Chetraj Pandit
4. Changes in individual and Social Activities:
• may neglect their bodily needs and personal hygiene.
• lose social sense.
• behave in an inappropriate manner in social situations and
embarrass others.
• They behave strangely with their family members,
friends, colleagues and others.
342/16/2020 Chetraj Pandit
5. Somatic complaints:
Patients may complaint of body aches and pains in different parts
of the body, fatigue, weakness, and involuntary movements.
6. Disturbances in motor behaviour:
Motor retardation, stupor, stereotypes, negativism, waxy
flexibility, echoprexia, restlessness, agitation and excitement.
352/16/2020 Chetraj Pandit
2/16/2020 36Chetraj Pandit
DEMENTIA
2/16/2020 37Chetraj Pandit
DEMENTIA
• Dementia is an acquired global impairment of intellectual, memory, and
personality but without impairment of consciousness.
• Alzheimer's disease is the most common cause of dementia.
• About the half of these disorders are of the Alzheimer’s type.
2/16/2020 38Chetraj Pandit
Prevalence of Dementia
• About 5% of persons older than 65 years have severe dementia,
• 20% of persons older than 80 years have severe dementia and 30% of
those > 85.
• Alzheimer's disease accounts for > 65% of dementias in the elderly.
• Alzheimer's disease is twice as common among women than men
2/16/2020 39Chetraj Pandit
Etiology of Dementia
1. Degenerating and irreversible causes
• Alzhemier’s disease ( most common of all dementing illness)
• Pick’s disease (atrophy in the frontal and temporal lobes of the brain)
• Huntington’s chorea (damage in the area of the basal ganglia and the cerebral
cortex)
• Parkinson’s disease
2/16/2020 40Chetraj Pandit
Etiology of Dementia…
2. Reversible causes
• Lesions in intracranial space.
• Metabolic disorder: Hepatic failure, renal failure.
• Endocrine disorder: Myxedema, addison’s disease.
• Infections- AIDS, Meningitis, encephalitis.
• Intoxication: Alcohol, heavy metal (lead, arsenic), chronic barbiturate poisoning.
• Anoxia: Anaemia, post anesthesia, chronic respiratory failure.
• Vitamin deficiency: Thiamine and nicotine vit B3.
• Miscellaneous: Heatstroke, epilepsy electric injury.
2/16/2020 41Chetraj Pandit
Etiology of Dementia…
3. Risk factors:
• Age: The risk of dementia goes up significantly with advancing age.
• Genetics/family history:
• Cholesterol: High levels of low-density lipoprotein (LDL) increase a person's risk of
developing vascular dementia.
• Diabetes:
• Smoking and alcohol use, atherosclerosis, down syndrome etc.
2/16/2020 42Chetraj Pandit
CLINICAL FEATURES
• Personality changes: lack of interest in day to day activities, easy mental
fatigability
• Memory impairment:
• Cognitive impairment: disorientation, poor judgment, decreased attention
span, or difficulty in abstraction.
• Affection impairment: Labile mood, irritableness
• Behavioral impairment: Stereotyped behavior, alteration in sexual drives
and activities.
2/16/2020 43Chetraj Pandit
CLINICAL FEATURES…
• Neurological impairment: seizures, headache
• Catastrophic reaction: Agitation, attempt to compensate for defects by
using strategies to avoid demonstrating failures in intellectual
performances, such as changing the subject.
• Sundowner syndrome: It is characterized by drowsiness, confusion, ataxia,
accidental falls, may occur at night.
• Course and prognosis: Insidious onset (more than 4 wks) but slow
progressive deterioration occurs.
2/16/2020 44Chetraj Pandit
TREATMENT
• Symptomatic treatments
• Cholinesterase inhibitors (e.g. donepezil 5-10 mg per oral once a day,
rivastigmine 1.5-6 mg per oral bid, galantamine 4-12 mg per oral bid)
• Benzodiazepines for insomnia and anxiety
• Antidepressants for depression
• Antipsychotics to alleviate hallucinations and delusions
• Anticonvulsants to control seizures
2/16/2020 45Chetraj Pandit
DELIRIUM
2/16/2020 46Chetraj Pandit
DELIRIUM
• Delirium is an acute organic mental disorder characterized by impairment of
consciousness, disorientation and disturbances in perception and restless.
Delirium is a syndrome not a disease
Epidemiology:
• 0.4% in general population,
• 1.1% in population of aged >55 years,
• 9–30% in general hospital admissions and
• 5–55% in elderly general hospital admissions, about
• 10-25% of medical surgical inpatients.
2/16/2020 47Chetraj Pandit
DELIRIUM
Etiology
• Vascular: Hypertensive encephalopathy, Cerebral
arteriosclerosis, Intracranial haemorrhage
• Infections: UTI, pneumonia, ulcer, sepsis, meningitis
• Neoplastic: Space occupying lesions
2/16/2020 48Chetraj Pandit
Etiology of Delirium…
• Drugs intoxication:
• Traumatic: Subdural and epideural hematoma, contusion, laceration
• Vitamin deficiency: Thiamine, niacin, pyridoxine, folic acid, B12
• Endocrine and metabolic:
• Anoxia: Anaemia, pulmonary or cardiac failure
• Metals: Heavy metals, carbon monoxide and toxins
2/16/2020 49Chetraj Pandit
Clinical Features of Delirium
• Impairment of consciousness: clouding of consciousness
• Impairment of attention
• Perceptual disturbances: most often visual
• Disturbances of cognition: Disorientation and impairment of immediate
and recent memory, impairment of abstract thinking.
2/16/2020 50Chetraj Pandit
Clinical Features of Delirium…
• Psychomotor disturbances: Hypo or hyperactivity, aimless groping or
picking at the bed clothes
• Disturbances of the sleep wake cycle: Insomnia
• Emotional disturbances: depression, anxiety, fear, irritability, euphoria
2/16/2020 51Chetraj Pandit
Course and prognosis
• The onset is usually abrupt.
• The duration of an episode is usually brief, lasting for about a week.
2/16/2020 52Chetraj Pandit
Differences between Delirium and Dementia
SN Features Delirium Dementia
a Onset Usually Acute Usually Insidious
b Course Usually recover in 1 week Usually prolonged
c Clinical Features
1 Consciousness Clouded Usually normal
2 Orientation Grossly disturbed, disoriented Usually normal, Disturbed
only in late stage
3 Memory Immediate retention and recall
disturbed
Immediate retention and recall
normal
Recent memory disturbed.
Remote memory disturbed
only in late stages
2/16/2020 53Chetraj Pandit
4 Comprehension Impaired Impaired only in later stage
5 Sleep Wake cycle Grossly disturbed Usually normal
6 Attention and
concentration
Grossly disturbed Usually normal
7 Diurnal Variation Sun downing present Usually normal in early stage, sun
downing present in later stage
8 Perception Visual illusion and
hallucination present
Hallucination may occur.
2/16/2020 54Chetraj Pandit
Prevention and treatment
Physical Interventions:
• Immediate correction eg. 50mg of 50% dextrose IV for hypoglycemia,
oxygen for hypoxia, IV fluids for fluid and electrolyte imbalance
• Environmental stimulation
• Cognitive Interventions: Place a clock and a calendar where the patient
can see them easily. Verbally reorient to time and place several times
over the course of the day.
• Psychological Interventions
2/16/2020 55Chetraj Pandit
TREATMENT
Pharmacologic Interventions
• 100 mg of Vitamin B1 IV for thiamine deficiency and IV fluids for fluid
and electrolyte imbalances
• Symptomatic measures: Benzodiazepine (Lorazepam or diazepam) or
antipsychotic (Haloperidol or rispiridon) may be given.
2/16/2020 56Chetraj Pandit
572/16/2020 Chetraj Pandit

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community mental health

  • 1. Community mental health Chetraj Pandit BPH,MPH Lecture, YCHS, Kathmandu, Nepal 2/16/2020 1Chetraj Pandit
  • 2. Mental health in community • Community services include: • Psychiatric wards of general hospitals, • local primary care medical services, • day centers or, • community mental health club houses centers, and • self-help groups for mental health. • The services may be provided by government organizations and mental health professionals, including specialized teams providing services across a geographical area, and may be provided by private or charitable organizations. 2/16/2020 2Chetraj Pandit
  • 3. • A community mental health program should : • Provide mental health care in the community itself • Focus services on the total community • Focus on the preventive and promote services • Provide continuing and comprehensiveness of services • Provide indirect services like consultation, mental health education etc. 2/16/2020 3Chetraj Pandit
  • 4. Types of Mental Illness Major illnesses are called psychoses (out of touch with reality). Major illnesses are: SCHIZOPHRENIA (Split Personality) – pt lives in a dream world of his own. MANIC DEPRESSIVE PSYCHOSES – symptoms vary from heights of excitement to depths of depression. PARANOIA – extreme suspicion & progressive tendency to regard the whole world in a framework of delusions. 2/16/2020 4Chetraj Pandit
  • 5. Types of Mental Illness Minor illnesses are 2 groups: NEUROSIS OR PSYCHONEUROSIS - pt is unable to react normally to life situations. Peculiar symptoms may occurs e.g. morbid fears, compulsions, obsessions. PERSONALITY & CHARACTER DISORDERS – legacy of unfortunate child hood experiences and perceptions. 2/16/2020 5Chetraj Pandit
  • 6. Mental disorder •A mental disorder, also called a mental illness, psychological disorder or psychiatric disorder, is mental or behavioral pattern that causes either suffering or a poor ability to function in ordinary life. 2/16/2020 6Chetraj Pandit
  • 7. Behavior disorder •Emotional and behavioral disorders (EBD) is a broad category which is used commonly in educational settings, to group a range of more specific perceived difficulties of children and adolescents. 2/16/2020 7Chetraj Pandit
  • 9. Introduction • Many factors are responsible for the causation of mental illness. These factors may predispose an individual to mental illness, precipitate or perpetuate the mental illness. 2/16/2020 9Chetraj Pandit
  • 10. Predisposing factors • Predisposing factors exist in the individual. These factors determine an individual susceptibility to mental illness. They interact with precipitating factors resulting in mental illness. These predisposing factors are: Genetic makeup: is the study of heredity Physical damage to the central nervous system Adverse psychological influences 2/16/2020 10Chetraj Pandit
  • 11. Precipitating factors (or exciting factors) • These are events that occur shortly before the onset of a disorder and appear to have induced it. Eg. death of loved one. 2/16/2020 11Chetraj Pandit
  • 12. • Physical Factors: These include infections, intoxications, endocrine, circulatory, nutritional disturbances and trauma. • Infections and Toxins: patients with hyperpyrexia, pneumonia, typhoid, scarlet fever, influenza, septicemia and syphilis. • Trauma: a fall from a height, forceps delivery or road traffic accident, a result of rape, natural disaster or loses. 122/16/2020 Chetraj Pandit
  • 13. Thus etiological factors of the mental illness can be grouped as follow: • Biological factors • Physiological factors • Psychological factors • Social factors 2/16/2020 13Chetraj Pandit
  • 14. Biological Factors include: • Heredity • Biochemical factors • Brain damage 2/16/2020 14Chetraj Pandit
  • 15. Heredity: • What one inherits is not the illness or its symptoms, but a predisposition to the illness, which is determined by genes that we inherit directly. Studies have shown that three fourths of mental defectives and one third of psychotic individuals owe their condition mainly to unfavourable heredity. 2/16/2020 15Chetraj Pandit
  • 16. Physiological Factors: • puberty, • menstruation, • pregnancy, • delivery, • puerperium and • climacteric. • These periods are marked not only by physiological (endocrine) changes but also by psychological issue that diminish the adaptive capacity of the individual. Thus individual becomes more susceptible to mental illness during this period. 2/16/2020 16Chetraj Pandit
  • 18. Introduction • The clinical manifestations are the end products of various forces of internal conflicts of the individual. The intensity and persistence of symptoms will indicate manifestation of the disease. 182/16/2020 Chetraj Pandit
  • 19. Signs and Symptoms of Mental Illness 1. Alterations of personality and behaviour 2. Alteration in the level of consciousness 3. Alterations of Biological Functions 4. Disturbances in Mental Functions: 5. Changes in individual and Social Activities: 6. Somatic complaints: 7. Disturbances in motor behaviour: 192/16/2020 Chetraj Pandit
  • 20. 1. Alteration in the level of consciousness: • may be in fully conscious, semiconscious, lethargic, somnolence, stupor, and coma. • Conscious: fully alert, aware of time, place and person. • Semiconscious: forgetfulness of an events or a person for a while, later remembers the situation. 202/16/2020 Chetraj Pandit
  • 21. • Lethargy: aware of stimuli, dull senses, and slow responses. • Somnolence: rarely awake, hardly aware of environmental stimuli. • Stupor: occasionally aware of environmental stimuli, forceful stimuli needed to bring awareness. • Coma: unconscious, variable response to stimuli, incontinence of faeces and urine. • Facial expression: dull, not interested. 212/16/2020 Chetraj Pandit
  • 22. 2. Disturbances in bodily functions • Sleep • Appetite and food intake • Biological function • Sexual desire and activity 222/16/2020 Chetraj Pandit
  • 23. • Sleep: • Disturbed sleep throughout the night, or • no sleep at all, or • difficulty in falling asleep, or • waking up in the middle of night and failing to asleep again. • lethargy and lack of freshness in the morning. 232/16/2020 Chetraj Pandit
  • 24. • Appetite and food intake: Increased or decreased appetite, weight loss or weight gain, nausea, vomiting. • Biological function: • Diarrhoea and constipation, increased micturation, bed wetting. • Persistent deviation in temperature, pulse and respiration, headache, pain, fatigue. 242/16/2020 Chetraj Pandit
  • 25. • Sexual desire and activity: • Decreased interest in sex, • premature ejaculation, • impotence or lack of sexual satisfaction. • In some condition there can be excessive sexual desire or lack of social inhibitions. 252/16/2020 Chetraj Pandit
  • 26. 3. Disturbances in Mental Functions: • Behaviour • Speech • Thought • Emotions • Perception • Attention and concentration • Memory • Intelligence and judgement • Insight: 262/16/2020 Chetraj Pandit
  • 27. • Behavior: • over activity, restlessness, irritability, may be abusive (for trivial or no responses at all) • dull, withdrawn and not respond to external and internal cues. • Sometimes the patient’s behaviour can be dangerous to self or others. 272/16/2020 Chetraj Pandit
  • 28. • Speech: • talks excessively and unnecessarily or talks very little or stays mute. • talk becomes irrelevant and un-understandable (in coherent). 282/16/2020 Chetraj Pandit
  • 29. • Thought: Patient expresses peculiar and wrong beliefs which other do not share. • Emotions: • Patient may exhibit excessive emotions like excessive happiness, anger, fear, or sadness. • Sometimes emotions can be inappropriate to situations (laugh to self or weep without any reason). 292/16/2020 Chetraj Pandit
  • 30. • Perception: The patient may perceive without any stimulus. There can be misinterpretation of perception. • Hallucinations (see things or hear sounds or feel objects which do not exist or others do not see). -Auditory, visual. 302/16/2020 Chetraj Pandit
  • 31. • Illusion (misperception of external stimuli) • Delusions (false, unshakable belief which is firmly held on inadequate grounds not affected by rational or logical arrangements) are of examples. 312/16/2020 Chetraj Pandit
  • 32. • Attention and concentration: • decreased attention and concentration: • he/she may get distracted easily, or • have selective in attention. • Memory: Patient may lose his memory and start forgetting important matters. 322/16/2020 Chetraj Pandit
  • 33. •Intelligence and judgement: •Deteriorating in intelligence and judgement. •loses reasoning skills and abilities (may not be able to perform simple arithmetic or commits mistakes in routine work). • Insight: Insight may be absent or present 332/16/2020 Chetraj Pandit
  • 34. 4. Changes in individual and Social Activities: • may neglect their bodily needs and personal hygiene. • lose social sense. • behave in an inappropriate manner in social situations and embarrass others. • They behave strangely with their family members, friends, colleagues and others. 342/16/2020 Chetraj Pandit
  • 35. 5. Somatic complaints: Patients may complaint of body aches and pains in different parts of the body, fatigue, weakness, and involuntary movements. 6. Disturbances in motor behaviour: Motor retardation, stupor, stereotypes, negativism, waxy flexibility, echoprexia, restlessness, agitation and excitement. 352/16/2020 Chetraj Pandit
  • 38. DEMENTIA • Dementia is an acquired global impairment of intellectual, memory, and personality but without impairment of consciousness. • Alzheimer's disease is the most common cause of dementia. • About the half of these disorders are of the Alzheimer’s type. 2/16/2020 38Chetraj Pandit
  • 39. Prevalence of Dementia • About 5% of persons older than 65 years have severe dementia, • 20% of persons older than 80 years have severe dementia and 30% of those > 85. • Alzheimer's disease accounts for > 65% of dementias in the elderly. • Alzheimer's disease is twice as common among women than men 2/16/2020 39Chetraj Pandit
  • 40. Etiology of Dementia 1. Degenerating and irreversible causes • Alzhemier’s disease ( most common of all dementing illness) • Pick’s disease (atrophy in the frontal and temporal lobes of the brain) • Huntington’s chorea (damage in the area of the basal ganglia and the cerebral cortex) • Parkinson’s disease 2/16/2020 40Chetraj Pandit
  • 41. Etiology of Dementia… 2. Reversible causes • Lesions in intracranial space. • Metabolic disorder: Hepatic failure, renal failure. • Endocrine disorder: Myxedema, addison’s disease. • Infections- AIDS, Meningitis, encephalitis. • Intoxication: Alcohol, heavy metal (lead, arsenic), chronic barbiturate poisoning. • Anoxia: Anaemia, post anesthesia, chronic respiratory failure. • Vitamin deficiency: Thiamine and nicotine vit B3. • Miscellaneous: Heatstroke, epilepsy electric injury. 2/16/2020 41Chetraj Pandit
  • 42. Etiology of Dementia… 3. Risk factors: • Age: The risk of dementia goes up significantly with advancing age. • Genetics/family history: • Cholesterol: High levels of low-density lipoprotein (LDL) increase a person's risk of developing vascular dementia. • Diabetes: • Smoking and alcohol use, atherosclerosis, down syndrome etc. 2/16/2020 42Chetraj Pandit
  • 43. CLINICAL FEATURES • Personality changes: lack of interest in day to day activities, easy mental fatigability • Memory impairment: • Cognitive impairment: disorientation, poor judgment, decreased attention span, or difficulty in abstraction. • Affection impairment: Labile mood, irritableness • Behavioral impairment: Stereotyped behavior, alteration in sexual drives and activities. 2/16/2020 43Chetraj Pandit
  • 44. CLINICAL FEATURES… • Neurological impairment: seizures, headache • Catastrophic reaction: Agitation, attempt to compensate for defects by using strategies to avoid demonstrating failures in intellectual performances, such as changing the subject. • Sundowner syndrome: It is characterized by drowsiness, confusion, ataxia, accidental falls, may occur at night. • Course and prognosis: Insidious onset (more than 4 wks) but slow progressive deterioration occurs. 2/16/2020 44Chetraj Pandit
  • 45. TREATMENT • Symptomatic treatments • Cholinesterase inhibitors (e.g. donepezil 5-10 mg per oral once a day, rivastigmine 1.5-6 mg per oral bid, galantamine 4-12 mg per oral bid) • Benzodiazepines for insomnia and anxiety • Antidepressants for depression • Antipsychotics to alleviate hallucinations and delusions • Anticonvulsants to control seizures 2/16/2020 45Chetraj Pandit
  • 47. DELIRIUM • Delirium is an acute organic mental disorder characterized by impairment of consciousness, disorientation and disturbances in perception and restless. Delirium is a syndrome not a disease Epidemiology: • 0.4% in general population, • 1.1% in population of aged >55 years, • 9–30% in general hospital admissions and • 5–55% in elderly general hospital admissions, about • 10-25% of medical surgical inpatients. 2/16/2020 47Chetraj Pandit
  • 48. DELIRIUM Etiology • Vascular: Hypertensive encephalopathy, Cerebral arteriosclerosis, Intracranial haemorrhage • Infections: UTI, pneumonia, ulcer, sepsis, meningitis • Neoplastic: Space occupying lesions 2/16/2020 48Chetraj Pandit
  • 49. Etiology of Delirium… • Drugs intoxication: • Traumatic: Subdural and epideural hematoma, contusion, laceration • Vitamin deficiency: Thiamine, niacin, pyridoxine, folic acid, B12 • Endocrine and metabolic: • Anoxia: Anaemia, pulmonary or cardiac failure • Metals: Heavy metals, carbon monoxide and toxins 2/16/2020 49Chetraj Pandit
  • 50. Clinical Features of Delirium • Impairment of consciousness: clouding of consciousness • Impairment of attention • Perceptual disturbances: most often visual • Disturbances of cognition: Disorientation and impairment of immediate and recent memory, impairment of abstract thinking. 2/16/2020 50Chetraj Pandit
  • 51. Clinical Features of Delirium… • Psychomotor disturbances: Hypo or hyperactivity, aimless groping or picking at the bed clothes • Disturbances of the sleep wake cycle: Insomnia • Emotional disturbances: depression, anxiety, fear, irritability, euphoria 2/16/2020 51Chetraj Pandit
  • 52. Course and prognosis • The onset is usually abrupt. • The duration of an episode is usually brief, lasting for about a week. 2/16/2020 52Chetraj Pandit
  • 53. Differences between Delirium and Dementia SN Features Delirium Dementia a Onset Usually Acute Usually Insidious b Course Usually recover in 1 week Usually prolonged c Clinical Features 1 Consciousness Clouded Usually normal 2 Orientation Grossly disturbed, disoriented Usually normal, Disturbed only in late stage 3 Memory Immediate retention and recall disturbed Immediate retention and recall normal Recent memory disturbed. Remote memory disturbed only in late stages 2/16/2020 53Chetraj Pandit
  • 54. 4 Comprehension Impaired Impaired only in later stage 5 Sleep Wake cycle Grossly disturbed Usually normal 6 Attention and concentration Grossly disturbed Usually normal 7 Diurnal Variation Sun downing present Usually normal in early stage, sun downing present in later stage 8 Perception Visual illusion and hallucination present Hallucination may occur. 2/16/2020 54Chetraj Pandit
  • 55. Prevention and treatment Physical Interventions: • Immediate correction eg. 50mg of 50% dextrose IV for hypoglycemia, oxygen for hypoxia, IV fluids for fluid and electrolyte imbalance • Environmental stimulation • Cognitive Interventions: Place a clock and a calendar where the patient can see them easily. Verbally reorient to time and place several times over the course of the day. • Psychological Interventions 2/16/2020 55Chetraj Pandit
  • 56. TREATMENT Pharmacologic Interventions • 100 mg of Vitamin B1 IV for thiamine deficiency and IV fluids for fluid and electrolyte imbalances • Symptomatic measures: Benzodiazepine (Lorazepam or diazepam) or antipsychotic (Haloperidol or rispiridon) may be given. 2/16/2020 56Chetraj Pandit

Editor's Notes

  1. Echoprexia:The immediate, involuntary, and repetitive echoing of words or phrases spoken by another.
  2. Comprehension=knowledge Diurnal Variation:A diurnal cycle is any pattern that recurs every 24 hours as a result of one full rotation of the Earth around its own axis