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Pneumonia
BY DR AZAD
Index :
 Difination
 Pathophysiology
 Causes
 Clinical Setting
 Sign and Symptoms
 Diagnostic Workup
 Treatment
 Prevention
 Complications
Difination
 Pneumonia is infection and inflammation of lung
paranchymal
Pathophysiology
How do we acquired infections?
 Inhalation
 Aspiration
 Hematogenous
Role of defense mechanism
Four stage of pneumonia
1. Congestion
2. Red hepatization
3. Gray hepatization
4. Reslotion
Causes
 Bacteria
 Viral
 Fungal
 others
Clinical Setting
1. Community Acquired Pneumonia
2. Nosocomial Pneumonia
 Hospital Acquired Pneumonia
 Ventilator Acquired Pneumonia
 Health care associated pneumonia
3. Aspiration Pneumonia
Sign and Symptoms
Signs :
 General signs
 Upper Respiratory Signs
 Pulmonary Signs
 GI Signs
Symptoms
Fever
Tachypnea
Hypotension
Diagnostic Workup
 Physical examination
 Laboratory examination
Physical examination
 Inspection
 Palpation
 Percussion
 Auscultation
Inspection
• Increase PR
• Use accessory respiratory muscles
• Intercostal retraction
• Pleuritic chest pain
Palpation
 Respiratory expansion
 Increase tactile fremitus
Percussion
Dullness
Auscultation
 Bronchial breathing sounds
 Crackles or Ralls
 Positive bronchophony
 Positive Egophony
 Positive Whispering piqtoriloqy
Lab Exam
 Chest X-ray
 CT Scan
 Sputum cytology
 Blood exam
Treatment
CAP
1_ OPD
✓ CAP + No comorbidities or No treat ABX
✓ CAP + comorbidities or treat ABX
2_ Inpatient
✓ Ward
✓ ICU
HAP
Treatment of CAP
OPD :
CAP + No comorbidities or No treat ABX
✓ Macrolides
✓ Doxycycline
Countinuse...
OPD:
CAP + comorbidities or treat ABX
✓ FQ
* Levofloxacin
* Gemifloxacine
* Ciprofloxacin
✓ Macrolides + Amoxicillin
or Augmentin
or 2th or 3th Gen of cef
Conti...
Inpatient
Ward :
✓ Ceftriaxone or Cefotaxium + Macrolides or FQ
If pencilin allergy :
* Aztereonam
ICU
Cephalosporin + Macrolides or quinolones
If MRSA :
Vancomycin or Linezolid
Treatment of HAP
1_NO MDR:
 Penicillin's
 3th gen of cephalosporin
 FQ
2_ MDR:
 Penicillin's ( Imipenem or Meropenem )
 Cefepem
 Ceftazedime
Prevention
Vaccination :
PPSV23
PCV13
Complications
 Septic shock
 Pleural effusion
 Meningitis
 Abscess
 Hypoxia

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Community Aquired Pneumonia by Dr mozammel.pptx