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A N O V E R V I E W
COLEUS FORSKOHLII
Coleus Forskohlii
What is Coleus forskohlii ?
 Forskolin (Also known as Coleonol) is a natural chemical that exists in the
roots of the plant Plectranthus Barbatus (Botanical name- Coleus
Forskohlii). This is a “power” herb in Ayurveda treatment and since ancient
times it has been used to treat various health ailments.
 Forskolin is a labdane diterpene and a research study of cell physiology
explored that this natural chemical raises the intracellular level of cyclic
AMP (cAMP) and also activates enzyme adenylyl cyclase, all these
consequently re-sensitize cell receptors.
 (cAMP) is a very crucial signal carrier which is required for the proper
biological response of cells to hormones, it is required for other
extracellular signals. It is also vital for the appropriate cell communication
in the hypothalamus/pituitary gland axis that results in accurate feedback
control of hormones. (cAMP) functions by activating cAMP sensitive
pathways such as Epac and protein Kinase.
 Coleus forskohlii extract is derived from Coleus Forskohilii’s root. Forskohlii
has a potential biological use.
Coleus Forskohlii Benefits
 When applied with rolipram, forskolin provides a path of inhibition of colon
cancer cell growth as well as survival.
 It results in vasodilation i.e. widening the blood vessels and thus relaxes smooth
muscle cells of the vessel walls.
 A clinical study has proved that this herb extract increases bone mass, lean
mass as well as testosterone in overweight men.
 It leads to weight loss
 It controls the primary cause of glaucoma.
 Controls as well as diminish urinary tract infection, it increases the
performance of antibiotics to kill bacteria.
 Forskolin is given intravenously to heal heart failure
 People suffering from asthma get relief by inhaling forskolin powder
 It also lowers asthma attach when taken in the form of capsules (Suggested
by Journal of
 International Medical Research)
 It is a powerful medicine to lower high blood pressure.
 It controls chest pain
Added Benefits
Forskolin when taken by mouth is known to treat the following health ailments
 Advanced cancer
 Allergies
 Bladder infection
 Blood clots
 Insomnia
 Irritable bowel syndrome
 Obesity
 Painful menstrual cycles
 Sexual problems in men
 Skin condition like psoriasis and eczema
 Urinary tract infection
(Note: No scientific information has proved that Coleus forskohlii extract is
effective when taken by mouth)
Conclusion
Forskolin has been seen as safe and
effective and has a great amount of
potential as a sports supplement.
As with most dietary ingredients, more
human research is needed but the future
looks bright for this compound.
Note: The information mentioned in this presentation is solely the opinion of the author and is published for informational purposes
only; Savesta Herbals or its affiliates bear no responsibility on the authenticity of the information published herein. Information
provided here is not intended to be used for treatments of any physical or neurological ailments. For any treatment one must
always take the doctor’s suggestion.

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Coleus forskohlii - An Overview

  • 1. A N O V E R V I E W COLEUS FORSKOHLII
  • 3. What is Coleus forskohlii ?  Forskolin (Also known as Coleonol) is a natural chemical that exists in the roots of the plant Plectranthus Barbatus (Botanical name- Coleus Forskohlii). This is a “power” herb in Ayurveda treatment and since ancient times it has been used to treat various health ailments.  Forskolin is a labdane diterpene and a research study of cell physiology explored that this natural chemical raises the intracellular level of cyclic AMP (cAMP) and also activates enzyme adenylyl cyclase, all these consequently re-sensitize cell receptors.  (cAMP) is a very crucial signal carrier which is required for the proper biological response of cells to hormones, it is required for other extracellular signals. It is also vital for the appropriate cell communication in the hypothalamus/pituitary gland axis that results in accurate feedback control of hormones. (cAMP) functions by activating cAMP sensitive pathways such as Epac and protein Kinase.  Coleus forskohlii extract is derived from Coleus Forskohilii’s root. Forskohlii has a potential biological use.
  • 4. Coleus Forskohlii Benefits  When applied with rolipram, forskolin provides a path of inhibition of colon cancer cell growth as well as survival.  It results in vasodilation i.e. widening the blood vessels and thus relaxes smooth muscle cells of the vessel walls.  A clinical study has proved that this herb extract increases bone mass, lean mass as well as testosterone in overweight men.  It leads to weight loss  It controls the primary cause of glaucoma.  Controls as well as diminish urinary tract infection, it increases the performance of antibiotics to kill bacteria.  Forskolin is given intravenously to heal heart failure  People suffering from asthma get relief by inhaling forskolin powder  It also lowers asthma attach when taken in the form of capsules (Suggested by Journal of  International Medical Research)  It is a powerful medicine to lower high blood pressure.  It controls chest pain
  • 5. Added Benefits Forskolin when taken by mouth is known to treat the following health ailments  Advanced cancer  Allergies  Bladder infection  Blood clots  Insomnia  Irritable bowel syndrome  Obesity  Painful menstrual cycles  Sexual problems in men  Skin condition like psoriasis and eczema  Urinary tract infection (Note: No scientific information has proved that Coleus forskohlii extract is effective when taken by mouth)
  • 6. Conclusion Forskolin has been seen as safe and effective and has a great amount of potential as a sports supplement. As with most dietary ingredients, more human research is needed but the future looks bright for this compound. Note: The information mentioned in this presentation is solely the opinion of the author and is published for informational purposes only; Savesta Herbals or its affiliates bear no responsibility on the authenticity of the information published herein. Information provided here is not intended to be used for treatments of any physical or neurological ailments. For any treatment one must always take the doctor’s suggestion.