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RUG and UMCG and world-class papers: 
how successful are we? 
Folkert Kuipers PhD 
Professor of Pediatrics 
Dean/Vice-Chairman Board UMCG 
No further disclosures 
CMB Symposium November 14th, 2014
UMCG 
University Medical Center Groningen 
Transparency: the ‘Etalage Project’ 
• A new Current Research The ‘Etalage’ Project: to be finished soon 
Management System (CRIS) 
will be implemented. 
• From this CRIS (PURE) both 
publication output (from a.o. 
WoS), other data (from 
PeopleSoft, press clippings, 
etc) and personal input 
(‘other positions’!) will/can be 
coupled to the Profile Pages. 
• In September a large 
introduction campaign will be 
started by CMB/UB and in 
October the PURE Portal will 
go ‘live’. 
• Easy to handle! 
See: www.rug.nl/bibliotheek/services/bibcmb/pure
It’s WE
Website RuG 
Nature and Science articles 
University of Groningen publications in 'Nature' and 'Science' 
Listed below is an overview of our publications in the prestigious scientific journals Nature 
and Science in 2011, 2012, 2013 and 2014, sorted by date. 
2014 
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche 
Source: NATURE Volume 514 Issue 7520 Pages: 92-97 
mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity 
Source: SCIENCE Volume 345 Issue 6204 Pages: 1579-+ 
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity 
Source: SCIENCE Volume 345 Issue 6204 Pages: 1578-+ 
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer 
Source: NATURE Volume 513 Issue 7518 Pages: 436-439 
Pseudo-three-dimensional maps of the diffuse interstellar band at 862 nm 
Source: SCIENCE Volume 345 Issue 6198 Pages: 791-795 
Jet acceleration of the fast molecular outflows in the Seyfert galaxy IC 5063 
Source: NATURE Volume 511 Issue 7510 Pages: 440-443 
Biological insights from 108 schizophrenia-associated genetic loci 
Source: NATURE Volume 511 Issue 7510 Pages: 421-427 
The ctenophore genome and the evolutionary origins of neural systems 
Source: NATURE Volume 510 Issue 7503 Pages: 109-114 
Electrically Switchable Chiral Light-Emitting Transistor 
Source: SCIENCE Volume 344 Issue 6185 Pages: 725-728 
Detection and replication of epistasis influencing transcription in humans 
Source: NATURE Volume 508 Issue 7495 Pages: 249-253 
Mapping the Epigenetic Basis of Complex Traits 
Source: SCIENCE Volume 343 Issue 6175 Pages: 1145-1148
Website RuG 
Nature and Science articles 
University of Groningen publications in 'Nature' and 'Science' 
Listed below is an overview of our publications in the prestigious scientific journals Nature 
and Science in 2011, 2012, 2013 and 2014, sorted by date. 
2014 
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche 
Source: NATURE Volume 514 Issue 7520 Pages: 92-97 
mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity 
Source: SCIENCE Volume 345 Issue 6204 Pages: 1579-+ 
Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity 
Source: SCIENCE Volume 345 Issue 6204 Pages: 1578-+ 
Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer 
Source: NATURE Volume 513 Issue 7518 Pages: 436-439 
Pseudo-three-dimensional maps of the diffuse interstellar band at 862 nm 
Source: SCIENCE Volume 345 Issue 6198 Pages: 791-795 
Jet acceleration of the fast molecular outflows in the Seyfert galaxy IC 5063 
Source: NATURE Volume 511 Issue 7510 Pages: 440-443 
Biological insights from 108 schizophrenia-associated genetic loci 
Source: NATURE Volume 511 Issue 7510 Pages: 421-427 
The ctenophore genome and the evolutionary origins of neural systems 
Source: NATURE Volume 510 Issue 7503 Pages: 109-114 
Electrically Switchable Chiral Light-Emitting Transistor 
Source: SCIENCE Volume 344 Issue 6185 Pages: 725-728 
Detection and replication of epistasis influencing transcription in humans 
Source: NATURE Volume 508 Issue 7495 Pages: 249-253 
Mapping the Epigenetic Basis of Complex Traits 
Source: SCIENCE Volume 343 Issue 6175 Pages: 1145-1148 
8/11 Contribution UMCG
UMCG publicaties in toptijdschriften 
Tijdschrift 2010 2011 2012 2013 2014* 
NATURE 1 4 4 0 5 
NATURE GENETICS 11 7 16 17 8 
NATURE REVIEWS 1 1 1 1 2 
NATURE BIOTECHNOLOGY 0 0 0 1 0 
SCIENCE 0 1 1 1 2 
LANCET 5 6 6 6 5 
NEJM 10 5 9 6 3 
CELL 0 0 0 2 0 
TOTAAL 28 24 37 34 25 
*Not yet complete 
Source Feiko Jilderda
Biochemistry & molecular biology 
Rank (based on 2013) 
total: 291 
Abbreviated Journal 
Title 
(linked to journal 
information) 
JCR Data 
Impact 
Factor 
5-Year 
Impact 
Factor 
1 CELL 33.116 35.020 
2 NAT MED 28.054 26.501 
Endocrinology & Metabolism 
Rank (based on 2013) 
total: 123 
Abbreviated Journal Title 
(linked to journal 
information) 
JCR Data 
Impact 
Factor 
5-Year 
Impact 
Factor 
1 ENDOCR REV 19.358 24.124 
1 CELL METAB 16.747 17.878 
Public Health, Environmental & Occupational (Science & Social Sciences) 
Rank (based on 2013) 
Total: 160 
Abbreviated Journal Title 
(linked to journal 
information) 
JCR Data 
Impact 
Factor 
5-Year 
Impact 
Factor 
1 INT J EPIDEMIOL 9.197 8.000 
Radiology, Nuclear Medicine & Medical Imaging 
Rank 
(based on 2013) 
Total: 121 
Abbreviated Journal Title 
(linked to journal 
information) 
JCR Data 
Impact 
Factor 
5-Year 
Imp act 
Factor 
1 JACC-CARDIOVASC IMAG 6.986 6.706
UMCG 
Graduate School of Medical Sciences 
Analysis PhD theses (june 2014) 
Number PhD theses analysed 2009 t/m 2013: 754 
Number of experimental chapters: 4528 
Average no. experimental chapters per thesis: 5.99 
Published at the day of PhD ceremony: 2510 56% 
Published today: 76% 
Published from years 2010/2011: 80% 
Median citations: 7 
Data collected by Kris Wijma
GSMS thesis analysis sept 2014 754 thesis 2009-2013 
Publ. 339 543 618 587 493 328 
80 
70 
60 
50 
40 
30 
20 
10 
0 
percentage (%) 
UMCG 
Graduate School of Medical Sciences 
Q1 
Q2 
Q3 
Q4 
2008 2009 2010 2011 2012 2013 
theses 112 140 136 149 179 181
UMCG 
GSMS thesis analysis publications per PhD category 
90 
80 
70 
60 
50 
40 
30 
20 
10 
0 
percentage (%) 
Q1 
Q2 
Q3 
Q4 
Graduate School of Medical Sciences
From: Bibliometric study on Dutch academic medical centers 1998-2012-2013 
CWTS (Meaningful metrics) – Conceptdocument 2014
Right: Skills becomes better and better by hard practice, but would be lost by 
playing around. 
Left: The journey will accomplished by thoughtful planning, but will not be 
accomplished by distractions 
Han Yu, 800 A.D., Guangdou, China

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RUG and UMCG and world-class papers: how successful are we? | Folkert Kuipers | Symposium How To Write A World-Class paper

  • 1. RUG and UMCG and world-class papers: how successful are we? Folkert Kuipers PhD Professor of Pediatrics Dean/Vice-Chairman Board UMCG No further disclosures CMB Symposium November 14th, 2014
  • 2. UMCG University Medical Center Groningen Transparency: the ‘Etalage Project’ • A new Current Research The ‘Etalage’ Project: to be finished soon Management System (CRIS) will be implemented. • From this CRIS (PURE) both publication output (from a.o. WoS), other data (from PeopleSoft, press clippings, etc) and personal input (‘other positions’!) will/can be coupled to the Profile Pages. • In September a large introduction campaign will be started by CMB/UB and in October the PURE Portal will go ‘live’. • Easy to handle! See: www.rug.nl/bibliotheek/services/bibcmb/pure
  • 4. Website RuG Nature and Science articles University of Groningen publications in 'Nature' and 'Science' Listed below is an overview of our publications in the prestigious scientific journals Nature and Science in 2011, 2012, 2013 and 2014, sorted by date. 2014 Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche Source: NATURE Volume 514 Issue 7520 Pages: 92-97 mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity Source: SCIENCE Volume 345 Issue 6204 Pages: 1579-+ Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity Source: SCIENCE Volume 345 Issue 6204 Pages: 1578-+ Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer Source: NATURE Volume 513 Issue 7518 Pages: 436-439 Pseudo-three-dimensional maps of the diffuse interstellar band at 862 nm Source: SCIENCE Volume 345 Issue 6198 Pages: 791-795 Jet acceleration of the fast molecular outflows in the Seyfert galaxy IC 5063 Source: NATURE Volume 511 Issue 7510 Pages: 440-443 Biological insights from 108 schizophrenia-associated genetic loci Source: NATURE Volume 511 Issue 7510 Pages: 421-427 The ctenophore genome and the evolutionary origins of neural systems Source: NATURE Volume 510 Issue 7503 Pages: 109-114 Electrically Switchable Chiral Light-Emitting Transistor Source: SCIENCE Volume 344 Issue 6185 Pages: 725-728 Detection and replication of epistasis influencing transcription in humans Source: NATURE Volume 508 Issue 7495 Pages: 249-253 Mapping the Epigenetic Basis of Complex Traits Source: SCIENCE Volume 343 Issue 6175 Pages: 1145-1148
  • 5. Website RuG Nature and Science articles University of Groningen publications in 'Nature' and 'Science' Listed below is an overview of our publications in the prestigious scientific journals Nature and Science in 2011, 2012, 2013 and 2014, sorted by date. 2014 Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche Source: NATURE Volume 514 Issue 7520 Pages: 92-97 mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity Source: SCIENCE Volume 345 Issue 6204 Pages: 1579-+ Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity Source: SCIENCE Volume 345 Issue 6204 Pages: 1578-+ Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer Source: NATURE Volume 513 Issue 7518 Pages: 436-439 Pseudo-three-dimensional maps of the diffuse interstellar band at 862 nm Source: SCIENCE Volume 345 Issue 6198 Pages: 791-795 Jet acceleration of the fast molecular outflows in the Seyfert galaxy IC 5063 Source: NATURE Volume 511 Issue 7510 Pages: 440-443 Biological insights from 108 schizophrenia-associated genetic loci Source: NATURE Volume 511 Issue 7510 Pages: 421-427 The ctenophore genome and the evolutionary origins of neural systems Source: NATURE Volume 510 Issue 7503 Pages: 109-114 Electrically Switchable Chiral Light-Emitting Transistor Source: SCIENCE Volume 344 Issue 6185 Pages: 725-728 Detection and replication of epistasis influencing transcription in humans Source: NATURE Volume 508 Issue 7495 Pages: 249-253 Mapping the Epigenetic Basis of Complex Traits Source: SCIENCE Volume 343 Issue 6175 Pages: 1145-1148 8/11 Contribution UMCG
  • 6. UMCG publicaties in toptijdschriften Tijdschrift 2010 2011 2012 2013 2014* NATURE 1 4 4 0 5 NATURE GENETICS 11 7 16 17 8 NATURE REVIEWS 1 1 1 1 2 NATURE BIOTECHNOLOGY 0 0 0 1 0 SCIENCE 0 1 1 1 2 LANCET 5 6 6 6 5 NEJM 10 5 9 6 3 CELL 0 0 0 2 0 TOTAAL 28 24 37 34 25 *Not yet complete Source Feiko Jilderda
  • 7. Biochemistry & molecular biology Rank (based on 2013) total: 291 Abbreviated Journal Title (linked to journal information) JCR Data Impact Factor 5-Year Impact Factor 1 CELL 33.116 35.020 2 NAT MED 28.054 26.501 Endocrinology & Metabolism Rank (based on 2013) total: 123 Abbreviated Journal Title (linked to journal information) JCR Data Impact Factor 5-Year Impact Factor 1 ENDOCR REV 19.358 24.124 1 CELL METAB 16.747 17.878 Public Health, Environmental & Occupational (Science & Social Sciences) Rank (based on 2013) Total: 160 Abbreviated Journal Title (linked to journal information) JCR Data Impact Factor 5-Year Impact Factor 1 INT J EPIDEMIOL 9.197 8.000 Radiology, Nuclear Medicine & Medical Imaging Rank (based on 2013) Total: 121 Abbreviated Journal Title (linked to journal information) JCR Data Impact Factor 5-Year Imp act Factor 1 JACC-CARDIOVASC IMAG 6.986 6.706
  • 8. UMCG Graduate School of Medical Sciences Analysis PhD theses (june 2014) Number PhD theses analysed 2009 t/m 2013: 754 Number of experimental chapters: 4528 Average no. experimental chapters per thesis: 5.99 Published at the day of PhD ceremony: 2510 56% Published today: 76% Published from years 2010/2011: 80% Median citations: 7 Data collected by Kris Wijma
  • 9. GSMS thesis analysis sept 2014 754 thesis 2009-2013 Publ. 339 543 618 587 493 328 80 70 60 50 40 30 20 10 0 percentage (%) UMCG Graduate School of Medical Sciences Q1 Q2 Q3 Q4 2008 2009 2010 2011 2012 2013 theses 112 140 136 149 179 181
  • 10. UMCG GSMS thesis analysis publications per PhD category 90 80 70 60 50 40 30 20 10 0 percentage (%) Q1 Q2 Q3 Q4 Graduate School of Medical Sciences
  • 11. From: Bibliometric study on Dutch academic medical centers 1998-2012-2013 CWTS (Meaningful metrics) – Conceptdocument 2014
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  • 16. Right: Skills becomes better and better by hard practice, but would be lost by playing around. Left: The journey will accomplished by thoughtful planning, but will not be accomplished by distractions Han Yu, 800 A.D., Guangdou, China