This document discusses components and considerations for clinical information systems (CIS). It describes the common components of a CIS including electronic medical records, clinical data repositories, clinical guidelines, and decision support tools. It also addresses important factors to consider when implementing a CIS such as cost, safety, security, education and training requirements. Selection of a CIS requires input from clinical staff and management to identify a system that meets the facility's needs and integrates with existing infrastructure. Ongoing support is also crucial for successful long-term use of a CIS.