The document contains 20 brief clinical cases presented by Dr. Juan Carlos Díaz Torre, a pediatric neonatologist. Each case presents a medical scenario and potential answers for the appropriate next step. The cases cover topics in obstetrics, psychiatry, dermatology, emergency medicine, and oncology. Screening for melanoma is discussed in the final case, noting that screening is not clinically proven to reduce mortality from the disease.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
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This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Evaluation of antidepressant activity of clitoris ternatea in animals
Clinical cases (2) may 12, 13
1. CURSO DE INGLÉS
ENGLISH COURSE
Dr. Juan Carlos Díaz Torre
Pediatra Neonatólogo
dr_diaz_torre@hotmail.com
(779) 100 - 40 - 26
DR.JCDT
1
2. BRIEF CLINICAL CASES
CASOS CLÍNICOS BREVES
(2)
Dr. Juan Carlos Díaz Torre
Pediatra Neonatólogo
dr_diaz_torre@hotmail.com
(779) 100 - 40 - 26
DR.JCDT
2
3. DR.JCDT
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CASE # 10
A 28-year-old primigravida is at 20 weeks
gestation by dates but her fundal height is
consistent with a 26-week gestation. She
has had episodes of vomiting during the
pregnancy that were more severe than the
physiologic vomiting typically seen in
pregnancy.
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CASE # 10
A sonogram performed at about 5 weeks
gestation for vaginal bleeding was normal
and showed a single fetus.
Which one of the following would be most
appropriate at this point?
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CASE # 10
a) Expectant management
b) A repeat sonogram
c) MRI of the pelvis
d) A serum HCG level
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CASE # 11
A 24-year-old male, new to your
practice, presents for a mental health
evaluation. The patient has a past history
of schizophrenia, diagnosed several years
ago.
Which one of the following, if
present, would lead to a reconsideration
of this diagnosis?
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CASE # 11
a) Loose associations
b) Elated mood
c) Social dysfunction
d) Auditory hallucinations
e) Incoherent speech
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CASE # 12
A previously healthy 22-year-old female
presents for her regular prenatal checkup
at 38 weeks gestation. She has a blood
pressure of 145/95 mm Hg today and this
is unchanged 1 hour later. Her blood
pressure was normal before pregnancy.
She is otherwise feeling well.
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CASE # 12
She has moderate edema at the ankles
and 3+ reflexes at the knees and ankles.
A urinalysis for protein is normal.
Given this presentation, which one of the
following is the most likely diagnosis?
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CASE # 12
a) Unmasked chronic hypertension
b) Hemolysis, elevated liver enzymes, low
platelets (HELLP) syndrome
c) Preeclampsia
d) Essential hypertension
e) Gestational hypertension
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CASE # 13
A 72-year-old female with longstanding
diabetes mellitus presents to your office.
During the review of systems, she
complains of difficulty voiding and
frequent “dribbling.”
A urinalysis is negative for infection and
her post-void residual volume is 250 mL.
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CASE # 13
Which one of the following is the most
likely cause of this patient’s urinary
incontinence?
a) Excess urine output due to
hyperglycemia
b) A grade II cystocele
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CASE # 13
a) Atrophic vaginitis
b) Asymptomatic bacteriuria
c) Autonomic neuropathy
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CASE # 14
A 3-year-old male is brought to your office
the day after he was stung by a honeybee.
He has developed a significant local
reaction, with redness and swelling
around the site of the sting on his forearm,
and also has had some swelling of his lips
for “a couple of hours.”
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CASE # 14
His mother removed the stinger and gave
him some oral diphenhydramine
(Benadryl). The local reaction has now
almost resolved and he has not had any
hives or respiratory distress.
Which one of the following is true
concerning this situation?
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CASE # 14
a) Systemic corticosteroids would be the
initial treatment of choice if the child
develops respiratory distress with his
next sting
b) An antibiotic that covers
Streptococcus pyogenes and
Streptococcus aureus should be
administered
17. DR.JCDT
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CASE # 14
c) If venom immunotherapy is begun, it
should be stopped after 2 years of
treatment
d) The child is at high risk for a systemic
reaction if he is stung again in the
future
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CASE # 14
e) Skin tests are not helpful in
confirming the presence of insect
sting allergy
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CASE # 15
Which one of the following is
characteristic of the first stage of labor?
a) An episiotomy should be performed
during this stage of labor
b) Uterine shape changes from discoid to
globular, along with a rise in fundal
height
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CASE # 15
c) In the absence of anesthesia, this stage
of labor typically lasts 20–50 minutes
d) Regular uterine contractions are
confirmed
e) In the absence of anesthesia, each
contraction stimulates the urge to
push
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CASE # 16
A 65-year-old white female develops a
burning pain in the left lateral thorax,
followed 2 days later by an erythematous
vesicular rash. Of the following, the best
treatment is:
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CASE # 16
a) Topical capsaicin (Zostrix)
b) Oral corticosteroids
c) Topical corticosteroids
d) Topical acyclovir (Zovirax)
e) Oral valacyclovir (Valtrex)
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CASE # 16
Which one of the following would be most
appropriate to treat a dental infection
requiring antibiotic therapy?
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CASE # 16
a) Cefixime (Suprax)
b) Penicillin
c) Dicloxacillin (Dynapen)
d) Erythromycin
e) Tetracycline
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CASE # 17
You are consulted for medical management
of a 45-year-old male, previously unknown
to you, who is hospitalized in the
psychiatric unit with paranoid
schizophrenia. His fasting blood glucose
level is 180 mg/dL.
Which one of the following medications is
the most likely cause of the hyperglycemia?
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CASE # 17
a) Alprazolam (Xanax)
b) Chlorpromazine (Thorazine)
c) Olanzapine (Zyprexa)
d) Haloperidol (Haldol)
e) Thiothixene (Navane)
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CASE # 18
A 22-year-old male presents to the
emergency department several hours after
a rugby match in which he was struck in
the face. His nose is bleeding.
On examination the patient has a
depression in his nose on the side of
impact and an outward displacement on
the opposite side.
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CASE # 18
Internal inspection reveals a purple area of
swelling and fluctuance on the left side of
the nasal septum. The remainder of the
examination demonstrates no findings to
suggest other facial or periorbital trauma.
Which one of the following would be most
appropriate at this time?
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CASE # 18
a) Immediate CT imaging to assess for
facial and mandibular fracture
b) Incision and drainage of the swollen,
fluctuant area
c) Immediate plain radiographs of the
nose and orbits
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CASE # 18
d) Immediate closed reduction of the
nasal fracture
e) Discharge with pain medication, ice
packs, and head elevation, with
referral to a specialist in 1 week
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CASE # 19
A 30-year-old gravida 3 para 2 at 28 weeks
gestation is a restrained passenger in a
high-speed motor vehicle accident. After
initial stabilization in the field with
supplemental oxygen and intravenous
fluids, she is brought into the emergency
department on a backboard and wearing a
cervical collar. Until you are able to rule
out a spinal injury, in what position should
the patient be kept?
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CASE # 19
a) Supine
b) Supine, with the uterus manually
deflected laterally
c) Prone
d) Trendelenburg’s pattern
e) Left lateral decubitus
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CASE # 20
Your hospital administrator asks you to
develop a community screening program
for melanoma.
Which one of the following is true
concerning screening for this disease?
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CASE # 20
a) Screening for melanoma is not
indicated since screening takes too
much time
b) No definite clinical evidence has
shown that screening for melanoma
reduces mortality
35. DR.JCDT
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CASE # 20
c) Screening for melanoma is not
indicated since the disease is rare
d) Because of sunbathing, female
patients are the most important
population to screen
36. Gracias por su atención
Dr. Juan Carlos Díaz Torre
Pediatra Neonatólogo
dr_diaz_torre@hotmail.com
(779) 100 – 40 - 26
DR.JCDT
36