This document defines and discusses the etiology, features, assessment, treatment planning and management of Class II division 1 malocclusions. Key points include:
- Class II division 1 malocclusions are characterized by proclined upper incisors and a large overjet. The etiology can include skeletal, dental, soft tissue and habit factors.
- Treatment planning depends on factors like age, difficulty, stability, and facial aesthetics. It may involve early treatment, functional appliances, fixed appliances with/without extractions, or growth modification/orthodontic camouflage/surgery.
- Stability after treatment requires full reduction of the overjet and achievement of lip competence through retention.
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Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
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Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
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Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Couples presenting to the infertility clinic- Do they really have infertility...
classII division 1 malocclusion
1. B Y: B AT O O L M O H A M M E D FA R H A N
CLASS II DIVISION 1
2. CONTENTS
Definition
Etiology
Occlusal features
Assessment of and treatment planning in Class II
division 1 malocclusions
Early treatment
Management of an increased overjet associated with a
Class I or mild Class II skeletal pattern
Management of an increased overjet associated with
a moderate to severe Class II skeletal pattern
Retention
3. DEFINITION
• is when the maxillary anterior teeth are proclined and a
large overjet is present.
4. ETIOLOGY
• Skeletal pattern
A Class II division 1 incisor relationship is usually
associated with a Class II skeletal pattern,
commonly due to a retrognathic mandible
5. ETIOLOGY
• Soft tissues
the resting position of the patient's soft tissues and their functional activity
also play a part.
in one of the following ways
• circumoral muscular activity
to achieve a lip-to-lip seal
• the mandible is postured forwards to allow the
lips to meet at rest
• the lower lip is drawn up behind the upper lndsors
• the tongue is placed forwards between the incisors to contact the
lower lip, often contributing to the development of an incomplete
overbite:
• Acombination of these
6. ETIOLOGY
• Dental factors
A Class II division 1 incisor relationship may occur
in the presence of crowding or spacing. Where the
arches are crowded, lack of space may result in
the upper incisors being crowded out of the arch
labially and thus to exacerbation of the overjet.
7. ETIOLOGY
• Habits
A persistent digit-sucking habit will act like an orthodontic
force upon the teeth if indulged in for more than a few
hours per day. The severity of the effects produced will
depend upon the duration and the intensity, but the
following are commonly associated with a determined habit
8. OCCLUSAL FEATURES
The overjet is increased
the upper incisors may be proclined or upright
The overbite is often increased
forward adaptive tongue position
a habit, or increased vertical skeletal proportions.
an anterior open bite
preexisting gingivitis.
9. ASSESSMENT OF AND TREATMENT
PLANNING IN CLASS II DIVISION 1
MALOCCLUSIONS
Factors influencing a definitive treatment plan
The patient's age
The difficulty of treatment
The likely stability of overjet reduction
The patient's facial appearance
10. ASSESSMENT OF AND TREATMENT
PLANNING IN CLASS II DIVISION 1
MALOCCLUSIONS
Practical treatment planning
The decision as to whether extractions are required will
depend upon
1. the presence of crowding
2. the tooth movements planned
3. their anchorage requirements
• Class Il division 1 malocclusions are commonly
associated with increased overbite, which must be
reduced before the overjet can be reduced.
• Overbite reduction requires space (about 1-2 mm for an
averagely increased overbite)
11. • Where the lower arch is well aligned and the molar relationship is Class
II, space for overjet reduction can be gained by distal movement of the
upper buccal segments or by extractions.
• a Class I buccal segment relationship is preferable.
• If extractions are carried out in the upper arch only, the molar
relationship at the end of treatment will be Class II.
• This is functionally satisfactory, but as half a molar width is narrower
than a premolar, some residual space often remains in the upper . arch.
• However with fixed appliances. the upper first molar can be rotated
mesiopalataJJy to take up this space by virtue of its rhomboid shape.
• is usually considered if the molar relationship is half a unit Class II or
less,
• a full unit of space can be gained in a co-operative, growing patient
12. • appliances have been developed which aim to produce
distal movement of the molars. These have been
classified as follows:
• Inter-maxillary: anchorage derived from within the arch -
anterior teeth, premolars, coverage of palatal vault.
• Intra-maxillary: anchorage derived from opposing arch.
In Class II cases this is the lower arch.
• Absolute anchorage: anchorage derived from implants.
Examples include microimplants and palatal implants.
13. EARLY TREATMENT
• Preadolescent children were randomized to either
observation or to early treatment with either a functional
appliance or headgear.
• Following this phase, patients underwent
comprehensive treatment with fixed appliances in the
permanent dentition.
• The results indicated that the early skeletal effects are
not maintained long-term.
• the time in fixed appliances was reduced for children
who underwent early treatment the overall treatment
time was considerably longer if the early treatment time
was included
14. EARLY TREATMENT
• At present many clinicians feel that treatment is best
deferred until the eruption of the secondary dentition
where space can be gained for relief of crowding and
reduction of the overjet by the extraction of permanent
teeth (if indicated),
• soft tissue maturity increases the likelihood of lip
competence.
• In the interim a custom-made mouthguard can be worn
for sports.
15. • if the upper incisors are thought to be at particular risk of
trauma during the mixed dentition, treatment with a
functional appliance can be considered
16. • Boy aged 9 years with
a Class II division 1
malocclusion on a
Class II skeletal
pattern.
• As the upper incisors
were at risk of trauma,
treatment was started
early with a functional
appliance.
17. • . Following eruption of the
permanent dentition, definitive
treatment involving the
extraction of all four second
premolars and the use of fixed
appliances was carried out to
correct the inter-incisal angle
and alleviate thecrowding
(note the retroclination of the
upper incisors as most of the
reduction of the overjet has
been achieved by
dentoalveolar change)
18. MANAGEMENT OF AN INCREASED
OVERJET ASSOCIATED WITH A CLASS I
OR MILD CLASS II SKELETAL PATTERN
• Fixed appliances, with extractions if indicated, will give
good results in skilled hands in this group
• In patients with moderately crowded arches. lower
second premolars and upper first premolars are a
common extraction pattern as this favours forward
movement of the lower molar to aid correction of the
molar relationship and retraction of the upper labial
segment.
19. CLASS II DIVISION 1 MALOCCLUSION
ON A CLASS I SKELETAL PATTERN
WITH CROWDING
20. • A functional appliance can be used to
A. reduce an overjet in a cooperative child with well-
aligned arches
B. a mild to moderate Class II skeletal pattern
• provided that treatment is timed for the pubertal growth
spurt
21. • In a limited number of cases with good arch alignment.
no crowding and proclined upper incisors a removable
appliance can be considered
22. MANAGEMENT OF AN INCREASED OVERJET
ASSOCIATED WITH A MODERATE TO SEVERE
CLASS II SKELETAL PATTERN
Management of the more severe case is the province of
the experienced operator.
There are three possible approaches to treatment
1. Growth modification
2. Orthodontic camouflage
3. Surgical correction
23. GROWTH MODIFICATION
• by attempting restraint of maxillary growth, by
encouraging mandibular growth, or by a combination of
the two
24. ORTHODONTIC CAMOUFLAGE
• using fixed appliances to achieve bodily retraction of the
upper incisors .
• The severity of the case that can be approached in this
way is limited by the availability of cortical bone palatal to
the upper incisors and by the patient's facial profile.
• If headgear is used in conjunction with this approach, a
degree of growth modification may also be produced in
favourably growing children.
25. PATIENT WITH CLASS II DIVISION 1 MALOCCLUSION ON A
MODERATELY SEVERE CLASS II SKELETAL PATTERN TREATED BY
ORTHODONTIC CAMOUFLAGE IN WHICH BOTH UPPER FIRST
PREMOLARS WERE EXTRACTED TO GAIN SPACE FOR OVERJET
REDUCTION AND FIXED APPLIANCES WERE USED FOR BODILY
RETRACTION OF THE UPPER INCISORS
26. SURGICAL CORRECTION
• In cases with a severe Class II skeletal pattern,
particularly where the I lower facial height is significantly
increased or reduced, a combination of orthodontics and
surgery may be required to produce an aesthetic and
stable correction of the malocclusion
• The threshold for surgery is lower in adults because of a
lack of growth.
27. RETENTION
• retention must be considered during treatment planning.
• Provided that the upper incisors have been retracted to a
position of soft tissue balance and are controlled by the
lower lip, the prognosis is good.
• To aid stability, full reduction of the overjet and the
achievement of lip competence is advisable.
• If the overjet is not fully reduced there is the risk that the
lower lip will continue to function behind the upper
incisors, with a subsequent relapse in incisor position.