Cirrhosis is a late stage of scarring (fibrosis) of the liver caused by many forms of liver diseases and conditions, such as hepatitis and chronic alcoholism. Each time your liver is injured — whether by disease, excessive alcohol consumption or another cause — it tries to repair itself.
3. I. Introduction
Definition
Cirrhosis is a late stage of scarring (fibrosis) of the liver caused by
many forms of liver diseases and conditions, such as hepatitis and
chronic alcoholism.
Each time your liver is injured — whether by disease, excessive alcohol
consumption or another cause — it tries to repair itself
Advanced cirrhosis is life-threatening.
4. Cause
The most common causes of cirrhosis are:
Alcohol-related liver disease
Hepatitis (B,C)
5. Clinical features
Cirrhosis often has no signs or symptoms
until liver damage is extensive.
When signs and symptoms do occur, they
may include:
9. III. Structure Microscopic Cell
Alcohol and hepatitis B and C are the most common causes of Chirrhosis.
Viral Hepatitis Cirrhosis
Macro-nodular cirrhosis
Nodular larger than 3mm
10. Chronic Alcoholism Cirrhosis
Micro-nodular cirrhosis
Develop over many years
Nodular are quite small averaging less than 3mm
11. Microscopic Cirrhosis
Nodules of hepatocytes are surrounded by
fibrous connective tissues
Proliferation of Bile duct( Neocanal Bile Duct )
Portal tracts: with this collagenous tissue are
scattered
12.
13. Cirrhosis
• Moderate fatty Change
( Macro-vesicular steatosis )
• Regenerative nodules surrounded by Fibrous
connective tissue extending between portal
regions