This document discusses the challenges of chronic diseases for healthcare systems. It notes that chronic diseases account for 60% of mortality worldwide and over 70% of health budgets in some countries. Examples are provided of high rates of chronic diseases in countries like Spain and the UK. The document then outlines experiences with chronic disease management programs in various regions that have led to lower rates of hospitalizations and emergency visits. It provides details on chronic disease prevalence and management initiatives in the Andalusia region of Spain, including eHealth platforms, electronic prescription, and telephone follow-up programs. Overall, the document advocates for proactive healthcare systems and self-management support to better address chronic diseases.