An infectious intestinal disease caused by Vibrio cholerae, cholera caused deadly outbreaks in Saudi Arabia in the 19th century. In 1808-1809, a major epidemic struck Najd, killing 30-40 people per day in Ad-Diriyah at its peak. This epidemic had economic impacts like increased food prices. Another outbreak occurred in 1814 in parts of Sudair, killing around 600 people in Jalajal. Treatment focuses on oral and intravenous rehydration to replace lost fluids.