This document discusses strategies for differentiating instruction with technology to support student needs. It begins by explaining Gardner's Multiple Intelligences theory and then provides examples of differentiating instruction by content, process, and product using technologies like accessing primary documents online and connecting with other classrooms. The document also discusses Response to Intervention, assistive technologies at different levels from low to high tech, supporting cognitive needs, and culturally responsive instructional strategies. Key assistive technologies mentioned include speech synthesizers, alternative keyboards, and captioning services.