Cell theory, fundamental scientific theory of biology according to which cell...jungutierrez8
Cell theory, fundamental scientific theory of biology according to which cells are held to be the basic units of all living tissues. First proposed by German scientists Theodor Schwann and Matthias Jakob Schleiden in 1838, the theory that all plants and animals are made up of cells marked a great conceptual advance in biology and resulted in renewed attention to the living processes that go on in cells.
This presentation you will get how the cell theory developed.
Robert Hooke observed cells in cork and coined the term "cells”.
Anton Van Leeuwenhoek observed first living cells under the simple microscope.
Matthias Schleiden (1838) German lawyer turned botanist, concluded that, despite differences in the structure of various tissues, plants were made of cells and that the plant embryo arose from a single cell.
In 1839, Theodor Schwann, a German zoologist and colleague of Schleiden’s, published a comprehensive report on the cellular basis of animal life. Schwann concluded that the cells of plants and animals are similar structures.
By 1855, Rudolf Virchow, a German pathologist concluded that
“Omnis cellula e cellula”- new cells are formed only from pre-existing cells.
All organisms are composed of one or more cells.
2) The cell is the structural unit of life.
3) Cells can arise only by division from a pre-existing cell
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Cell theory, fundamental scientific theory of biology according to which cell...jungutierrez8
Cell theory, fundamental scientific theory of biology according to which cells are held to be the basic units of all living tissues. First proposed by German scientists Theodor Schwann and Matthias Jakob Schleiden in 1838, the theory that all plants and animals are made up of cells marked a great conceptual advance in biology and resulted in renewed attention to the living processes that go on in cells.
This presentation you will get how the cell theory developed.
Robert Hooke observed cells in cork and coined the term "cells”.
Anton Van Leeuwenhoek observed first living cells under the simple microscope.
Matthias Schleiden (1838) German lawyer turned botanist, concluded that, despite differences in the structure of various tissues, plants were made of cells and that the plant embryo arose from a single cell.
In 1839, Theodor Schwann, a German zoologist and colleague of Schleiden’s, published a comprehensive report on the cellular basis of animal life. Schwann concluded that the cells of plants and animals are similar structures.
By 1855, Rudolf Virchow, a German pathologist concluded that
“Omnis cellula e cellula”- new cells are formed only from pre-existing cells.
All organisms are composed of one or more cells.
2) The cell is the structural unit of life.
3) Cells can arise only by division from a pre-existing cell
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
2. DISCOVERY OF CELLS
- Most cells cannot be seen with naked eye.
- So how were they first discovered?
- What was needed for their discovery?
3. CELLS DISCOVERED
- ROVERT HOOKE (1665)
- Use basic microscope to look at
thin slices of plant tissues- cork
- Looked empty, like monk’s
chamber
- Called tiny chambers “cells”.
4. ANTON VAN LEEUWEHHOEK (1673)
- First to view pond water
organisms
- First to see living
microscopic organisms
- Made careful sketches.
5. MATTHIAS SCHLEIDEN (1838)
- German botanist
- All plants tooked at were made
of cells.
- He concluded “ All plants are
made of cells.”
6. THEODORE SCHWANN (1839)
- German scientist who
studied animals- zoologist.
- Saw that all animals he
studied were cellular.
- Concluded “All animals are
made of cells.”
7. RUDOLF VIRCHOW (1855)
- German physician who studied
cell reproduction
- “Where a cell exists, there must
have been a pre- existing cells.”
8. THE CELL THEORY
THREE PRINCIPLES OF CELL THEORY
- All living organisms are composed of one or more cells.
- Cell is the basic structural and functional unit of living
organisms.
- All cells arise from pre-existing cells.
