Describing the new CDCF project for tagging Systematic reviews - synergistic plan with the MASCOT (Multilateral Association for Studying Health Inequalities and Enhancing North-South And South-South Cooperation – is funded by the European Commission under the Seventh Framework Programme for Research and Technological Development (FP7).f7th project
This presentation provides an overview of communities of practices in healthcare and opportunities to apply them globally using emerging technologies. A community of practice (CoP) is a group of people from a common profession that share knowledge and experiences with each other so that they can grow personally and professionally. CoP often share with each other educational materials and best practices, meet online with peers to discuss the implementation of best practices, and meet regularly with colleagues for consultation and mentoring, and support. Communities of practices can become one of the most important sources of support for professionals and current knowledge. Communities of practice can also help to advance the profession by refining the implementation of best practices to new situations and environments. Communities of practice have expanded significantly in the last decade using online technologies that allow groups to communicate worldwide. This presentation will provide examples of implemented communities of practices, the barriers and facilitators, and opportunities for application using online and mobile technologies.
This presentation provides an overview of communities of practices in healthcare and opportunities to apply them globally using emerging technologies. A community of practice (CoP) is a group of people from a common profession that share knowledge and experiences with each other so that they can grow personally and professionally. CoP often share with each other educational materials and best practices, meet online with peers to discuss the implementation of best practices, and meet regularly with colleagues for consultation and mentoring, and support. Communities of practices can become one of the most important sources of support for professionals and current knowledge. Communities of practice can also help to advance the profession by refining the implementation of best practices to new situations and environments. Communities of practice have expanded significantly in the last decade using online technologies that allow groups to communicate worldwide. This presentation will provide examples of implemented communities of practices, the barriers and facilitators, and opportunities for application using online and mobile technologies.
The Joint Learning Network in Action: Spotlight on GhanaHFG Project
More and more countries are implementing complex health systems reforms to achieve universal health coverage. The Joint Learning Network (JLN) is a country-driven network of practitioners and policymakers who together develop knowledge products to bridge the gap between theory and practice, with the goal of extending health care coverage to more than 3 billion people.
The JLN community is comprised of leaders from ministries of health, national health financing agencies, and other key government institutions in 27 Asian, African, European, Latin American, and Middle Eastern countries as well as a diverse group of international, regional, and local partners.
On Thursday, September 22, the HFG Project hosted a technical briefing session on the JLN's work on the ground, and about Ghana’s National Health Insurance Authority (NHIA) on their collaboration with the JLN and the HFG project. Speakers included: Amanda Folsom (JLN Program Director, Results for Development), Nathaniel Otoo, (Chief Executive, Ghana NHIA), Dr. Lydia Dsane-Selby (Director, Claims, NHIA), and Chris Lovelace (Principal Associate, International Health, Abt Associates).
An evaluation of the Route to Success resources, related tools and frameworks covering disease specific areas: heart failure; advanced kidney disease; dementia; and long term neurological conditions
13 December 2012 - Institute of Healthcare Management / National End of Life Care Programme
This project set out to review how the series of publications and supporting tools, resource guides and frameworks developed and supported by the National End of Life Care Programme (NEoLCP) have been utilised across four disease specific pathways.
The disease specific pathways to be included in the review are:
Heart Failure
Advanced Kidney Disease
Dementia
Long term neurological conditions
Publication by the National End of Life Programme which became part of NHS Improving Quality in May 2013
Dr. Niranjan Bose
POLICY SEMINAR
Tackling child undernutrition at scale: Insights from national and subnational success cases
Co-Organized by IFPRI and Exemplars in Global Health
APR 1, 2021 - 09:30 AM TO 11:00 AM EDT
Achievements and Implications of HIV Prevention Programme among Injecting Dru...QUESTJOURNAL
Background: The HIV epidemic appears to be generalized with new infections occurring among persons perceived to be practicing low risk sex in Bayelsa State. The epidemic appeared to be concentrated among the sub-populations including injecting drug users (IDUs). Intervention therefore needed to ameliorate this problem hence, this paper presents achievements of HIV prevention programme among IDUs in Bayelsa state including its implications for programming. Methods: This was an intervention project conducted among injecting drug users in five purposive selected local government areas (LGAs) in Bayelsa State, Nigeria. Centre for Development and Empowerment of Commercial Motorcyclist (CEDECOM) was engaged by Bayelsa State Agency for Control of AIDS and funded under the HIV and AIDS fund (HAF) II project to scale up HIV prevention among injecting drug users. The project was carried out between April, 2016 and January, 2017. The estimated sample size for this intervention was 210 IDUs and minimum prevention package intervention (MPPI) was adopted in the implementation of this project activities. Data were entered on DHIS2 platform and later exported and analyzed using Microsoft Excel. Data were presented using descriptive statistics such as percentage, simple proportion and frequency. Results: The overall target population reached during this intervention was 440 given a target reached of 209.5%. All the 36 community dialogues that took place during the course of this project occurred in the first quarter with a total number of 54 male influencers participated in dialogues and sensitization activities during this period. A total number of 440 peers were registered during this period and a total number of 11,346 male condoms and 656 female condoms were distributed. A total of 243 (55.2%) of the registered peers were reached with all the three stages of MPPI and 427 (97.0%) were reached with HCT. Among these, 21 (4.9%) were tested positive to HIV. Conclusion: This intervention was a success as it scaled up HIV prevention services among injecting drug users in the state. To optimize the effectiveness of this type of intervention in reducing HIV infection among this risk group, future programs should be based on principles related to equity and gender balance.
HFG Rapid Assessment of TB Payment and PFM Systems in Cambodia: Lessons Learn...HFG Project
Despite substantial funding for tuberculosis (TB) prevention and treatment over the last 10 years, both by donors and governments, the worldwide incidence of TB remains troubling. Across lower- and middle-income countries, access to TB services is limited, and the quality of TB services is often substandard. Many countries face questions over the long-term financial sustainability of their efforts to prevent and treat the disease. Cambodia has one of the highest rates of TB in the world, with prevalence and incidence rates sitting at roughly 660 and 437 per 100,000 people, respectively (WHO 2015). Meanwhile, donor funding for TB is declining, the government is struggling to generate new resources for TB, and out-of-pocket spending still accounts for a significant share of health and TB expenditures. Cambodia needs to identify mechanisms to improve the efficiency of TB spending (i.e., mechanisms for spending money wisely). In the short term, this may mean finding ways to improve outputs – such as access, use of services, and quality – for a given level of spending on TB. In the long term, Cambodia and countries facing similar challenges may be interested in finding ways to achieve better outputs with fewer resources.
Cambodia was the subject of one of several country case studies linking strategic TB purchasing with improved efficiency and better outcomes. In May/June 2016, HFG conducted a brief but in-depth assessment of health purchasing/provider payment and PFM systems in Cambodia, to identify rigidities and barriers.
I need these questions answered in about 200 words each and not plag.docxflorriezhamphrey3065
I need these questions answered in about 200 words each and not plagiarized. Please include each answer with references.
MODULE 1
Q1
Defining international or global health is important and some consider global health synonymous with public health. Select one of the following two statements:
1. Global health is public health requiring similar training and research methods.
2. Global health is a separate discipline requiring specific training and research methods.
Identify at least two arguments that support the selected statement and provide sources to support those arguments. Identify and discuss one historical event that is important in how global health is understood today and how that event supports your argument. For one of your substantive responses, identify another classmate that selected the opposite statement and provide at least one point of agreement and one point of disagreement.?
Q2
Poverty is central to health and development in low-income and middle-income countries. State your definition of poverty prior to studying public health. Based on this definition, what would be the focus of poverty alleviation solutions? Based on the relational and spiritual definition of poverty, discuss how the focus of solutions would change to include a holistic approach. Identify an example of a health program or solution that integrates a relational definition of poverty. Watch the video on "Defining Poverty" to help in responding to this discussion question.
RESOURCES
Read Chapter 4 in For the Love of God: Principles and Practice of Compassion in Missions.
Read "The Stages of International (Global) Health: Histories of Successes or Successes of History?" by Birn, from
Global Public Health
(2009). URL:
https://lopes.idm.oclc.org/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=edsbl&AN=RN243322709&site=eds-live&scope=site
Watch the "Introduction to PUB 655" video in the Participatory Community Development playlist, located in the Student Success Center. This video will explain the overall purpose and focus for this course. The course begins with a broad perspective and then concentrates specifically on engaging communities and vulnerable populations with a focus on Christian health missions. URL:
https://www.gcumedia.com/lms-resources/student-success-center/v3.1/#/media-element/CONHCP/002E95E4-E032-E811-8F95-005056A072B6
Watch the "Defining Poverty" video in the Participatory Community Development playlist, located in the Student Success Center, in preparation for responding to the discussion question in this topic. The video provides an alternative definition of poverty based on relationships rather than only material need. This definition informs one's approach to poverty and engaging lower-income communities. URL:
https://www.gcumedia.com/lms-resources/student-success-center/v3.1/#/media-element/CONHCP/002E95E4-E032-E811-8F95-005056A072B6
Read "Towards a Common Definition of Global Health" by Koplan, Bond,.
The Joint Learning Network in Action: Spotlight on GhanaHFG Project
More and more countries are implementing complex health systems reforms to achieve universal health coverage. The Joint Learning Network (JLN) is a country-driven network of practitioners and policymakers who together develop knowledge products to bridge the gap between theory and practice, with the goal of extending health care coverage to more than 3 billion people.
The JLN community is comprised of leaders from ministries of health, national health financing agencies, and other key government institutions in 27 Asian, African, European, Latin American, and Middle Eastern countries as well as a diverse group of international, regional, and local partners.
On Thursday, September 22, the HFG Project hosted a technical briefing session on the JLN's work on the ground, and about Ghana’s National Health Insurance Authority (NHIA) on their collaboration with the JLN and the HFG project. Speakers included: Amanda Folsom (JLN Program Director, Results for Development), Nathaniel Otoo, (Chief Executive, Ghana NHIA), Dr. Lydia Dsane-Selby (Director, Claims, NHIA), and Chris Lovelace (Principal Associate, International Health, Abt Associates).
An evaluation of the Route to Success resources, related tools and frameworks covering disease specific areas: heart failure; advanced kidney disease; dementia; and long term neurological conditions
13 December 2012 - Institute of Healthcare Management / National End of Life Care Programme
This project set out to review how the series of publications and supporting tools, resource guides and frameworks developed and supported by the National End of Life Care Programme (NEoLCP) have been utilised across four disease specific pathways.
The disease specific pathways to be included in the review are:
Heart Failure
Advanced Kidney Disease
Dementia
Long term neurological conditions
Publication by the National End of Life Programme which became part of NHS Improving Quality in May 2013
Dr. Niranjan Bose
POLICY SEMINAR
Tackling child undernutrition at scale: Insights from national and subnational success cases
Co-Organized by IFPRI and Exemplars in Global Health
APR 1, 2021 - 09:30 AM TO 11:00 AM EDT
Achievements and Implications of HIV Prevention Programme among Injecting Dru...QUESTJOURNAL
Background: The HIV epidemic appears to be generalized with new infections occurring among persons perceived to be practicing low risk sex in Bayelsa State. The epidemic appeared to be concentrated among the sub-populations including injecting drug users (IDUs). Intervention therefore needed to ameliorate this problem hence, this paper presents achievements of HIV prevention programme among IDUs in Bayelsa state including its implications for programming. Methods: This was an intervention project conducted among injecting drug users in five purposive selected local government areas (LGAs) in Bayelsa State, Nigeria. Centre for Development and Empowerment of Commercial Motorcyclist (CEDECOM) was engaged by Bayelsa State Agency for Control of AIDS and funded under the HIV and AIDS fund (HAF) II project to scale up HIV prevention among injecting drug users. The project was carried out between April, 2016 and January, 2017. The estimated sample size for this intervention was 210 IDUs and minimum prevention package intervention (MPPI) was adopted in the implementation of this project activities. Data were entered on DHIS2 platform and later exported and analyzed using Microsoft Excel. Data were presented using descriptive statistics such as percentage, simple proportion and frequency. Results: The overall target population reached during this intervention was 440 given a target reached of 209.5%. All the 36 community dialogues that took place during the course of this project occurred in the first quarter with a total number of 54 male influencers participated in dialogues and sensitization activities during this period. A total number of 440 peers were registered during this period and a total number of 11,346 male condoms and 656 female condoms were distributed. A total of 243 (55.2%) of the registered peers were reached with all the three stages of MPPI and 427 (97.0%) were reached with HCT. Among these, 21 (4.9%) were tested positive to HIV. Conclusion: This intervention was a success as it scaled up HIV prevention services among injecting drug users in the state. To optimize the effectiveness of this type of intervention in reducing HIV infection among this risk group, future programs should be based on principles related to equity and gender balance.
HFG Rapid Assessment of TB Payment and PFM Systems in Cambodia: Lessons Learn...HFG Project
Despite substantial funding for tuberculosis (TB) prevention and treatment over the last 10 years, both by donors and governments, the worldwide incidence of TB remains troubling. Across lower- and middle-income countries, access to TB services is limited, and the quality of TB services is often substandard. Many countries face questions over the long-term financial sustainability of their efforts to prevent and treat the disease. Cambodia has one of the highest rates of TB in the world, with prevalence and incidence rates sitting at roughly 660 and 437 per 100,000 people, respectively (WHO 2015). Meanwhile, donor funding for TB is declining, the government is struggling to generate new resources for TB, and out-of-pocket spending still accounts for a significant share of health and TB expenditures. Cambodia needs to identify mechanisms to improve the efficiency of TB spending (i.e., mechanisms for spending money wisely). In the short term, this may mean finding ways to improve outputs – such as access, use of services, and quality – for a given level of spending on TB. In the long term, Cambodia and countries facing similar challenges may be interested in finding ways to achieve better outputs with fewer resources.
Cambodia was the subject of one of several country case studies linking strategic TB purchasing with improved efficiency and better outcomes. In May/June 2016, HFG conducted a brief but in-depth assessment of health purchasing/provider payment and PFM systems in Cambodia, to identify rigidities and barriers.
I need these questions answered in about 200 words each and not plag.docxflorriezhamphrey3065
I need these questions answered in about 200 words each and not plagiarized. Please include each answer with references.
MODULE 1
Q1
Defining international or global health is important and some consider global health synonymous with public health. Select one of the following two statements:
1. Global health is public health requiring similar training and research methods.
2. Global health is a separate discipline requiring specific training and research methods.
Identify at least two arguments that support the selected statement and provide sources to support those arguments. Identify and discuss one historical event that is important in how global health is understood today and how that event supports your argument. For one of your substantive responses, identify another classmate that selected the opposite statement and provide at least one point of agreement and one point of disagreement.?
Q2
Poverty is central to health and development in low-income and middle-income countries. State your definition of poverty prior to studying public health. Based on this definition, what would be the focus of poverty alleviation solutions? Based on the relational and spiritual definition of poverty, discuss how the focus of solutions would change to include a holistic approach. Identify an example of a health program or solution that integrates a relational definition of poverty. Watch the video on "Defining Poverty" to help in responding to this discussion question.
RESOURCES
Read Chapter 4 in For the Love of God: Principles and Practice of Compassion in Missions.
Read "The Stages of International (Global) Health: Histories of Successes or Successes of History?" by Birn, from
Global Public Health
(2009). URL:
https://lopes.idm.oclc.org/login?url=http://search.ebscohost.com/login.aspx?direct=true&db=edsbl&AN=RN243322709&site=eds-live&scope=site
Watch the "Introduction to PUB 655" video in the Participatory Community Development playlist, located in the Student Success Center. This video will explain the overall purpose and focus for this course. The course begins with a broad perspective and then concentrates specifically on engaging communities and vulnerable populations with a focus on Christian health missions. URL:
https://www.gcumedia.com/lms-resources/student-success-center/v3.1/#/media-element/CONHCP/002E95E4-E032-E811-8F95-005056A072B6
Watch the "Defining Poverty" video in the Participatory Community Development playlist, located in the Student Success Center, in preparation for responding to the discussion question in this topic. The video provides an alternative definition of poverty based on relationships rather than only material need. This definition informs one's approach to poverty and engaging lower-income communities. URL:
https://www.gcumedia.com/lms-resources/student-success-center/v3.1/#/media-element/CONHCP/002E95E4-E032-E811-8F95-005056A072B6
Read "Towards a Common Definition of Global Health" by Koplan, Bond,.
Unit 5Instructions Enter total points possible in cell C12, under.docxmarilucorr
Unit 5Instructions: Enter total points possible in cell C12, under the rubric. Next enter scores (between 0 and 4) into yellow cells only in column F.Evidence-Based Clinical Question SearchUnsatisfacotrySatisfactoryAverageExcellentScoreWeightFinal Score1234Identify your refined PICOT question.IncompleteN/AN/AComplete05%0.00Using PubMed and the Cochrane collaboration database, do a systematic review of your clinical question.IncompleteN/AN/AComplete010%0.00Describe your systematic review and include an errors analysis.IncompleteN/AN/AComplete010%0.00Determine an evidence-based quantitative article from the search that contains an evidence-based randomized control trial.IncompleteN/AN/AComplete010%0.00Summarize the case study selected.IncompleteN/AN/AComplete05%0.00Describe the study approach, sample size, and population studied.IncompleteN/AN/AComplete05%0.00Apply the evidence from this review to your practice specifically in your overview.IncompleteN/AN/AComplete010%0.00Evaluate the outcomes, identifying the validity and reliability.IncompleteN/AN/AComplete010%0.00Discuss if the study contained any bias.IncompleteN/AN/AComplete010%0.00Determine the level of evidence identified in the review.IncompleteN/AN/AComplete010%0.00LengthLess than 7 pages8 pages9 pages10 pages 05%0.00Format/StyleDid not follow APA formatMajor errors with APA formattingText, title page, and references page follow APA guidelines . Minor references and grammar errorsText, title page and references page follow APA guidelines. No grammar, word usage or punctuation errors. Overall style is consistent with professional work.010%0.00100%0.00Final Score0Percentage0.00%Total available points =2504Rubric ScoreGrade pointsPercentageLowHighLowHighLowHigh3.54.022525090%100%2.53.4920022580%89.99%1.72.4917520070%79.99%1.01.6915017560%69.99%0.01.000150059.99%Comments:
Running head: EFFECTIVE OBESITY MANAGEMENT 1
EFFECTIVE OBESITY MANAGEMENT 2
Effective Obesity Management
Kaplan University
Topic Selection 42/42
EBP Overview 48/48
Length 6/6
Format/Style 20/24
Total 116/120 Outstanding paper with APA errors.
Introduction
With this paper, I will share my research topic question, after much consideration, I came across the best way to address the question and yield evidence based practice results. My question is: is bariatric surgery effective in yielding long term success when compared to lifestyle changes, in the obese population? I will also include the use of reputable reliable search resources such as Cochrane Database. There are significant healthcare issues that can be addressed within my area of specialty, and the focus in healthcare should be to create a better environment where best healthcare decisions can be made. The understanding of these healthcare issues provides a better environment where better pr ...
Getting to the Heart of the Matter: Communities and Health Systems Strengtheningjehill3
Getting to the Heart of the Matter: Communities and Health Systems Strengthening
The State of CORE
Karen LeBan, Executive Director, CORE Group
CORE Spring Meeting, April 27,2010
Canada’s Rare Disease Drug Program
Vision: Integrated, Inclusive, Innovative Rare Drug System
Single Seamless Pathway from R&D, CT, regulatory approval, access parameters, monitoring, values-based assessment, price negotiations
Governance board representing all stakeholders: diverse patient community, clinical specialities, public/private drug plan providers, HTA agencies, pharmaceutical companies, subject matter experts (regulatory, research)
Building for Success: 12 Steps, 4 Platforms
Partnering with Patients, Families and Communities for Health: A Global Imper...EngagingPatients
Engagement is an essential tool to improving global health. This report introduces a new framework for engagement to help countries assess current programs and think strategically about future engagement opportunities. It spotlights barriers to engagement and offers concrete examples of effective engagement from around the globe.
Our aim is to alleviate human suffering related to diabetes and its complications among those least able to withstand the burden of the disease. From 2002 to March 2017, the World Diabetes Foundation provided USD 130 million in funding to 511 projects in 115 countries. For every dollar spent, the Foundation raises approximately 2 dollars in cash or as in-kind donations from other sources. The total value of the WDF project portfolio reached USD 377 million, excluding WDF’s own advocacy and strategic platforms.
Early child development: Report on case studiesDRIVERS
Case study produced as part of the DRIVERS project. The objective of case studies in areas that are key drivers of health inequities is to identify services, policies or practices that are already in place that have the potential to reduce inequalities in health and its social determinants.
Better Health? Composite Evidence from Four Literature ReviewsHFG Project
The Marshaling the Evidence secretariat agreed that a cross-cutting synthesis paper was necessary to frame the work in the wider context of governance in health systems, drawing distinctions and consensus across all four TWG papers. Members of the secretariat, some of whom also were members of the TWGs, conducted the analysis across each TWG report and wrote the synthesis report. The report compiles results from the TWGs into a searchable database, contained in Annex 1. The report also lays the foundation for future action—from dissemination to further research agendas and policy plans.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
1. Welcome to the CDCF meeting
20th Cochrane Collaboration Colloquium / Auckland - New Zealand
Tuesday 2 October 2012 - 15:30 - 17:00
Location: Regatta D
Dr. Mario Tristan
CDCF Coordinator from IHCAI Foundation
presented by
Dr. Regina El Dib
Faculdade de Medicina de Botucatu (FMB)
Universidade Estadual Paulista "Júlio de Mesquita Filho” – Brazil
2. The new CDCF
In December 2006 the group was officially registered as Cochrane Developing
Countries Network (CDCN) which became the Cochrane Developing
Countries Field (CDCF) in 2010.
The CDCF is based in IHCAI FOUNDATION -COSTA RICA- since 2007.
This decision was taken during the XV Cochrane Colloquium in Sao Pablo,
Brazil, 2007.
3. The new CDCF the decision and the
challenge
During some years we need to admit, the production of the CDCN
and after CDCF was very limited …
Given this we analyzed the situation and some considered that the
filed should be closed.
However during the Madrid 19 Cochrane Colloquium we discussed
this during the fields meeting and closed meeting with the
participation of Mario Tristan, L. Susan Wieland from Monitoring and
Registration Committee, Ashraf Nabhan from Egypt and Damian
Francis from Jamaica agreed to keep the CDCF for one more year –
All agreed that was needed to re-launching the CDCF and making it
effective accordingly with the inspirational aim of the field.
4. The agreement ….
“After a meeting held in Costa Rica in 2008, the group was trying to strengthen and motivate itself, but its
actions were severely limited by a lack of resources and a previous weak strategic plan that contained no
concrete short-term goals that could be useful for other Cochrane entities.
This was particularly important, as it would have proved the importance of our field.
In October 2011, a meeting was held in Madrid, regarding the state of the CDCF and whether or not it was
advisable to continue it in the same way it was created, given the difficulties the CDCF was experiencing in
achieving its goals.
The core functions of Cochrane Fields were reviewed at this meeting, and ways in which the CDCF could
meet these core functions were discussed. It was decided that the best course of action would be to
continue the Field, as the proposed activities of the CDCF related to the core functions are of great
importance to global health issues.
Through this and other meetings held digitally, we have continued this project, developing a working plan
that has a high resource production without the high cost. It was also agreed to name a coordinating
committee that, for the span of one year, will work together to identify several measurable short-term goals
that will serve as the foundation of long-term success in meeting core functions and goals of the CDCF. In
this way we hope to support the future development of our Field. As such, the current committee was
started with the people present.”
Taken from Current State and 2012 Module => http://dcf.cochrane.org/current-state-and-2012-module
6. This Year 2012 cont..
CDCF is currently led by Dr. Mario Tristan, along with an
executive assistant and regional coordinator from the
following regions: China, Eastern Europe, Latin America,
Middle East and North Africa, South East Asia and the
Pacific, and South Asia. However, the actions and
responses to the secretariat calls have obviously
decreased, probably because of the changes occurred
during 2008, the lack of funding to convey the original
action plan, and of course to some extend the lack of
effective communication between the secretariat and
the regional representatives during 2009.
7. Tagging Systematic Reviews for low
and middle income countries
Image taken from => http://dcf.cochrane.org/current-state-and-2012-module
8. 2012 Module the crucial task…
“This year we have re evaluated our methods, and decided that the best
course of action is the creation of criteria for the identification of Cochrane
Reviews that are important for developing countries.
After this criteria is stated a framework must be produced to tag Cochrane
reviews with a stated level of importance , which will allow us to both focus
efforts in dissemination of existing Cochrane evidence that is relevant to
developing countries, and to identify geographical and topic gaps where
Cochrane evidence has yet to be produced, This will facilitate the content
relevance of The Cochrane Library content in Developing Countries, since
even though the research production of developing country authors has
increased to 38%,meny topic relevant to the developing world and the best
way to address problems that affect large populations, still remain neglected.
To initiate tagging, we need to produce a list of possible, reliable contributors
willing to go along with the project”.
Taken from => http://dcf.cochrane.org/current-state-and-2012-module
9. First, we need to make us visible …
We are now in …
LINK: https://www.facebook.com/CochraneDCF
LINK: https://twitter.com/CochraneDCF
10. The CDCF newsletter
FIND it at : http://www.cochrane.org/sites/default/files/uploads/Newsletters/cdcf-
news.html
11. And we have BLOG
LINK: http://Cochranedevelopingcountriesfield.wordpress.com
12. The rationale for tagging
systematic reviews:
Responding the needs of LOW and
MIDDLE income countries burden of
diseases.
13. “Having those numbers helps health authorities determine whether they are focussing on the
right kinds of public health actions that will reduce the number of preventable deaths and
disease. Globally, around 57 million people die each year. Almost 15% of these deaths occur in
children under the age of 5. Most of these preventable deaths in children occur in low- and
middle-income countries.” Source => Global Health Observatory (GHO).
http://www.who.int/gho/mortality_burden_disease/en/index.html. Consulted August 14 2012.
14. Source Global Health Observatory (GHO) http://www.who.int/gho/child_health/mortality/causes/en/index.html#
Consulted August 14 -2102
15. The tagging: Target groups
WE ARE CONSIDERING TO POTENTIAL USER:
INTERNAL - THE COCHRANE GROUPS AND AUTHORS.
EXTERNAL - CLINICIANS AT THE POINT OF CARE ND
POLICY MAKERS IN L&MIC.
16. THE HIGHER EVIDENCE QUALITY
THE HIGHER THE RELEVANCE !!!
THERE ARE SYSTEMATICS REVIEWS THAT BECAUSE OF THE QUALITY OF FINDINGS ARE
RELEVANT FOR ANY COUNTRY.
THERE IS VARIATION ON HTE POWER OF SYSTEMATICS REVIEWS MUTS OF THE TIMES
FOR LACK OF GOOD QUALITY STUDIES .
WE ARE USING THE SAME GRADE GROUP CATEGORIES FOR SCORING TAGGED
SYSTEMATIC REVIEWS.
HIGH => Further research is very unlikely to change our confidence in the estimate of
effect.
MODERATE => Further research is likely to have an important impact on our confidence
in the estimate of effect and may change the estimate.
LOW => Further research is very likely to have an important impact on our confidence
in the estimate of effect and is likely to change the estimate.
17. THE TOPICS BASED ON THE BURDEN
OF DISEASES
HIGH PRIORTY THEMES
Child and women health.
Infectious diseases in adults.
Chronic diseases in children and adults
Occupational diseases .
Disaster mitigation .
Health care services.
Behavioural and learning disorders in adults.
Other no included in these topics.
18. WE STARTED:
CHILD AND MOTHER (WOMEN)
HEALTH RELEVANT TOPICS
beyond health care... Antibiotics reviews
“1- Irrational prescribing and drug resistance make an important, but overlooked,
contribution to the inequities of the medical poverty trap. For example, in India, 52%
of out-of-pocket health expenditure went towards medicines and fees, as did 71% of
in-patient expenditure...
2-Vietnam’s high frequency of antibiotic resistance is a clear indication of the adverse
health effects of inappropriate drug sales and irrational consumption.32 In a poor
region of Mexico, 74% of health-care visits resulted in inadequate treatment or
advice, especially from traditional healers or retail drug sellers.33 On average, the
equivalent of 13 days minimum wage was spent unnecessarily per patient, in 1
month, because of inadequate prescribing…
Poor people receive ineffective, or even dangerous treatment, including inappropriate
or inadequate antituberculosis treatment regimens, …”
Source => Whitehead, M et all “Equity and health sector reforms: can low-income countries
escape the medical poverty trap? THE LANCET • Vol 358 • September 8, 2001
19. T he following Cochrane groups
were included in this first stage
and are shown in order of relevancy
according to burden of diseases
in very low-income countries…
20. 1. Neonatal Group -291 Active published reviews.
2. Cochrane Pregnancy and Childbirth Group- 471 Active published reviews.
3. Cochrane Infectious Diseases Group- 126 Active published reviews.
4. Cochrane HIV/AIDS Group- 117 Active published reviews.
5. Sexually Transmitted Infections Group- 12 Active published reviews.
6. Public Health Group – 23 Active published reviews.
7. Menstrual disorders and Fertility group- Active 210 published reviews.
8. Cochrane Cystic Fibrosis and Genetic Disorders Group-Active 129
published reviews.
9. Cochrane Breast Cancer Group- 44 Active published reviews.
10. Cochrane Childhood Cancer Group- 31 Active published reviews.
11. Pain, Palliative and Supportive Care Group- 195 Active published reviews.
12. Cochrane Gynaecological Cancer Group- Active 129 published reviews.
13. TOTAL : 1778
SOURCE : ARCHIE, MAY-AUGUST , 2012
21. Examples of tagged (1)
Systematic reviews
Antibiotic regimens for suspected early neonatal sepsis (Review)
Mtitimila EI, Cooke RWI. Antibiotic regimens for suspected early neonatal sepsis. Cochrane Database
of Systematic Reviews 2004, Issue 4. Art. No.: CD004495. DOI: 10.1002/14651858.CD004495.pub2.
Editorial group: Cochrane Neonatal Group.
Publication status and date: Edited (no change to conclusions), published in Issue 1, 2009.
Review content assessed as up-to-date: 15 June 2004.
SCORE : LOW
THE OBJECTIVE OF THIS REVIEW:
To compare antibiotic monotherapies, monotherapy with combination therapy, and
combination therapies for empirical treatment of suspected early neonatal sepsis (within
48 hours after birth), for both effectiveness and adverse effects.
THE REVIEW RESULTS ARE NOT CONCLUSIVE BECAUSE LACK OF EVIDENCE
“…. There were no differences between the two groups. Both of the studies were
published in the 1980s and are probably out of date. The authors of this review concluded
that there is no evidence for using a particular kind of antibiotic for early neonatal sepsis.
…”
22. Examples of tagged (2)
Systematic reviews
Antibiotic regimens for suspected late onset sepsis in newborn infants
Gordon A, Jeffery HE. Antibiotic regimens for suspected late onset sepsis in newborn infants. Cochrane
Database of Systematic Reviews 2005, Issue 3. Art. No.: CD004501. DOI: 10.1002/14651858.CD004501.pub2.
Review content assessed as up-to-date: 1 March 2005.
The authors WROTE “…In developing countries infection is estimated to cause 30 - 40% of neonatal deaths
(WHO 1999).
SCORE : LOW
THE OBJECTIVE OF THIS REVIEW:
To compare the effectiveness and adverse effects of different antibiotic regimens for treatment
of suspected late onset sepsis in newborn infants.
THE REVIEW RESULTS ARE NOT CONCLUSIVE BECAUSE LACK OF EVIDENCE
Authors’ conclusions…
There is inadequate evidence from randomised trials in favour of any particular antibiotic
regimen for the treatment of suspected late onset neonatal sepsis. The available evidence is not
of high quality. Although suspected sepsis and antibiotic use is common, quality research is
required to specifically address both narrow and broad-spectrum antibiotic use for late onset
neonatal sepsis. Future research also needs to assess cost effectiveness and the impact of
antibiotics in different settings such as developed or developing countries and lower gestational
age groups.
23. OTHER TAGGED SR ON RELATED TOPICS
ANTIBIOTICS AND CHILD AND MATERNAL HEALTH TAGGED SYSTEMATIC REVIEWS
REVIEW GROUP EVIDENCE QUALITY AND RELAVANCE FOR LMIC LAST UPDATE
POWER FOR MAIN
OUTCOME
Antibiotic adjuvant therapy for Cochrane Cystic Fibrosis and LOW MODERATE Published Online: 6 OCT 2010
pulmonary infection in cystic fibrosis Genetic Disorders Group Assessed as up-to-date: 8 SEP 2010
Antibiotic regimens for the empirical Cochrane Neonatal Group LOW HIGH Published Online: 15 AUG 2012
treatment of newborn infants with . Assessed as up-to-date: 18 FEB 2012
necrotising enterocolitis
Antibiotic prophylaxis for cesarean Cochrane Pregnancy and LOW HIGH Published Online: 20 JAN 2010
section Childbirth Group Assessed as up-to-date: 4 MAR 2002
Antibiotic prophylaxis for operative Cochrane Pregnancy and Published Online: 21 JAN 2009
vaginal delivery Childbirth Group Assessed as up-to-date: 30 AUG 2008
Antibiotic prophylaxis for third- and Cochrane Pregnancy and LOW HIGH Published Online: 10 NOV 2010
fourth-degree perineal tear during Childbirth Group Assessed as up-to-date: 3 OCT 2010
vaginal birth
Antibiotic regimens for endometritis Cochrane Pregnancy and HIGH HIGH Published Online: 21 JAN 2009
after delivery Childbirth Group Assessed as up-to-date: 22 MAY 2002
Antibiotic regimens for management of Cochrane Pregnancy and OUTDATED HIGH Publication status and date: Edited (no change
intraamniotic infection Childbirth Group to conclusions), published in Issue 9, 2011.
Review content assessed as up-to-date: 22 May
2002.
Antibiotics for meconium-stained Cochrane Pregnancy and OUTDATED HIGH Publication status and date: Edited (no change
amniotic fluid in labour for preventing Childbirth Group to conclusions), published in Issue 9, 2011.
maternal and neonatal infections Review content assessed as up-to-date: 22 May
2002
Antibiotics for preterm rupture of Cochrane Pregnancy and LOW HIGH Publication status and date: New search for
membranas Childbirth Group studies and content updated (conclusions
changed), published in Issue 8, 2010. Review
content assessed as up-to-date: 6 July 2010.
24. Doing synergy: Stakeholders and allies
tagging SR for child and maternal health
Taken from => http://www.mascotfp7.eu/
25. MASCOT - F7
partners in developing countries
FUNDACION INSTITUTO CENTROAMERICANO DE
SALUD INTERNACIONAL (COSTA RICA)
http://www.ihcai.org
Dr. Mario Tristan – mtristan@ihcai.org
CENTRE FOR HEALTH POLICY – UNIVERSITY OF
THE WITWATERSRAND JOHANNESBURG (SOUTH
AFRICA)http://www.wits.ac.za/chp
Prof. Matthew Chersich –
matthew.chersich@wits.ac.za
NATIONAL INSTITUTE FOR MEDICAL RESEARCH
(TANZANIA)
http://www.nimr.or.tz
Dr. Michael Munga – michaelmunga@yahoo.com
26. MASCOT-F7
partners in developing countries… (contd.)
SCHOOL OF PUBLIC HEALTH – UNIVERSITY OF GHANA
(GHANA) http://sph.ug.edu.gh
Dr. Patricia Akweongo – akweongo@gmail.com
HOPITAL FARHAT HACHED DE SOUSSE (TUNISIA)
http://www.epidemiologie-sousse.org
Prof. Hassen Ghannem – hassen.ghannem@rns.tn
UNIVERSIDAD CATOLICA DE LA SANTISIMA CONCEPCION
(CHILE)
http://www.ucsc.cl
Dr. Patricia Marcela Cortes Jofre – p.cortes@ucsc.cl
INSTITUTO NACIONAL DE SALUD PUBLICA (MEXICO)
http://www.insp.mx
Dr. Victor Becerril Montekio – victor.becerril@insp.mx
27. NEXT STEP …
WE WILL UPLOAD THE TAGGED REVIEWS TO
ARCHIE ON OCTOBER 30 – 2012
IF ANY OF YOU IS INTERESTED TO JOIN US IS VERY WELCOME
SIGN UP HERE
OR EMAIL US TO
Cochrane Developing Countries Field Secretariat
cdcf@cochrane.ihcai.org>
This the rationale of the of the work flow for CDCF -
We want this to be very interactive with potential authors and users of Cochrane Systematic reviews .focusing on all those interested in Developing countries
The rationale we adapted and changed the method described by Susan Wieland for first stage topic selection…
Mapping the deaths we can indentified where the problem is …
The question can we give good quality evidence using the Cochrane SR for attempt to reducing child mortality ?
The tagging results target groups
RELEVANT TOPICS ACCORDING TO THE BURDEN OF DISEASES OF LMIC …..The antibiotics inadequate prescribing even for a health professional is a severe problem in low and middle incomes . This is the reason we started tagging antibiotics SR for child and women health …
60 % of these groups reviews have been a analyzed … and tagged when related for burden of diseases related or the quality of evidence synthesised in the review is scored HIGH .
PLEASE NOTE THAT BOTH RS HAS NOT BEEN UPDATED MORE THAN FIVE YEAR AGO ……