Andreessen Horowitz has more than doubled its annual investments in 2021. The document analyzes a16z's investments over the past 5 years and identifies key trends, including increased investments in blockchain/crypto, the metaverse, marketplaces, gaming, and creator platforms. Many of a16z's largest deals in 2021 have been in blockchain/crypto, though it also remains active in enterprise, fintech, healthcare, and other industries.