An Oracle PL/SQL API can provide several benefits as a data protection mechanism: 1) It enforces consistent updates, authorized access, and protects against misbehaved applications through mechanisms like triggers, constraints, and virtual private databases. 2) It controls access to data structures and prevents dependency on the underlying data model through validation procedures and abstracted retrieval/update types. 3) It avoids issues caused by direct database access like "funny" updates, mal-formed queries, and sub-optimal access paths by funneling all data handling through the API.