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Cardiovascular Risk Detection in SARS-CoV-2
using Machine Learning
Authors: MD ASMA, NOVERA HABEEB ,
HEENA KHANUM
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications- July 14-15,2023
Presenter: MD ASMA, Associate Professor, CSE Dept
LORDS Institute of Engineering and Technology (A), Hyderabad, Telangana, INDIA.
In CSIR SPONSERED SYMPOSIUM
Organized by
International School of Technology and Sciences for Women
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
Presenter Name : MD ASMA
Qualification : B.Tech- JNTUH, M.Tech-JNTUH,
Pursuing Ph.D
Teaching Experience : 16yrs
Publications : 4
BIOGRAPHY
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
ABSTRACT
• Almost 17.9 million people are losing their lives due to
CardioVascular Disease, which have increased after the COVID-19
pandemic to 32% of total death throughout the world.
• Technologies like MCGs help in detecting these diseases in early
stage, but expensive, unfit for smaller clinics, time-consuming and
sensitive to tangential causes
• With AI entering and Machine Learning models, This study is
aimed at building a potential machine learning model to predict
heart disease in early stage .
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
INTRODUCTION
Cardiovascular disease (CVD) is a
general term that describes a
disease of the heart or blood
vessels.
Blood flow to the heart, brain or
body can be reduced because of a:
•blood clot (thrombosis)
•build-up of fatty deposits inside an
artery, leading to the artery
hardening and narrowing
(atherosclerosis)
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
Types of CVD
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
•Pre-existing cardiovascular disease (CVD) increases the morbidity
and mortality of COVID-19 and is strongly associated with poor
disease outcomes.
•However, SARS-CoV-2 infection can also trigger acute and
chronic cardiovascular disease.
Acute cardiac complications include arrhythmia, myocarditis
and heart failure, which are significantly associated with higher
in-hospital mortality.
The possible mechanisms by which SARS-CoV-2 causes this
acute cardiac disease include direct damage caused by viral
invasion of cardiomyocytes as well as indirect damage through
systemic inflammation.
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
•The Multifunction Cardiogram (MCG) is a kind of non-
invasive diagnostic tool for measuring the health of a
patient’s heart
•The MCG uses a systems approach to modeling the heart
and then comparing these models to a demographically
appropriate risk-stratified database of similar patients using
166 indices with that database to aid both in the diagnosis
and in predicting patient needs and outcomes.
•Expensive, unfit for smaller clinics, time-consuming and
sensitive to tangential causes
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
•Researchers are employing artificial intelligence (AI) in an effort to mine new
medical information that can be used by clinicians to better understand the
symptoms of various diseases and, as a result, make more informed decisions
for patients
•The use of artificial intelligence (AI) and massive amounts of data in the
prediction of CVD models is becoming increasingly common.
•In view of the growing popularity of machine learning techniques, The
traditional machine learning models that were tested and evaluated based on
UCI Heart Disease dataset is used to having 14 columns and over 300
samples..
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
METHODOLOGY
Classification methods:
Models such as Random forest (RF), decision tree classifier (DT), K-
Nearest Neighbors(KNN), Support Vector Machine (SVM) are
used
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
Implementation
Dataset: 300 entries of UCI Heart Disease dataset with 14
columns(data likeage,sex,cp,trestbp,chol,fbs)
Implementation platform: Google collaboratory using PYTHON
Packages used: Numpy
Pandas
Sci-kit
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
EXPERIMENTAL ANALYSIS
 The experiments focused on the performance of KNN using the datasets
and features.
 As the name says, a k neighbors classifier takes a data point and
finds k other data points nearest to it in the vector space. In a
supervised fashion, KNN creates clusters of the data samples having
the same target value. Whenever a new value needs to be classified,
it uses a distance metric to assign it to one of the classes. For heart
disease detection, there are only two classes that KNN needs to build
 For the first set of results the training dataset was divided at random into
five folds, with training on four of the five folds, and testing on the
remaining fold.
 Models were trained on data set and achieved accuracy 91.5% with KNN
Model.
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
EXPERIMENTAL ANALYSIS
 List the dataset Perform EDA
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
EXPERIMENTAL ANALYSIS
 Train the data on CP data values
 The limited subset of the attributes we encoded and scaled. For
instance, the chest pain data variable expanded
into cp_0, cp_1, cp_2, and cp_3. This normalized and engineered
dataset will be appropriate for training.
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
EXPERIMENTAL ANALYSIS
 Using the KNeighborsClassifier module we build a KNN
model and iteratively tune the
hyperparameter n_neighbors (number of neighbours to
be checked for every data point).
 Models were trained on data set and achieved accuracy 91.5%
with KNN Model.
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
EXPERIMENTAL ANALYSIS
 The experiments focused on the performance of KNN using the
datasets and features
 Models were trained on data set and achieved accuracy 91.5% with
KNN Model.
Algorithm Accuracy
Random Forest 86.8%
KNN 91.8%
Decision Tree 85.2%
SVM 90.1%
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
CONCLUSION
To conclude, Early identification of heart disease of improved
diagnosis and high-risk individuals using a prediction model can
be recommended for a fatality rate reduction, and decision-
making is improved for further treatment and prevention.
National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio
Medical Applications July 14-15,2023
Thankyou…!!

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Cardiovascular Risk Detection in SARS - CoV-2 suing ML

  • 1. Cardiovascular Risk Detection in SARS-CoV-2 using Machine Learning Authors: MD ASMA, NOVERA HABEEB , HEENA KHANUM National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications- July 14-15,2023 Presenter: MD ASMA, Associate Professor, CSE Dept LORDS Institute of Engineering and Technology (A), Hyderabad, Telangana, INDIA. In CSIR SPONSERED SYMPOSIUM Organized by International School of Technology and Sciences for Women
  • 2. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 Presenter Name : MD ASMA Qualification : B.Tech- JNTUH, M.Tech-JNTUH, Pursuing Ph.D Teaching Experience : 16yrs Publications : 4 BIOGRAPHY
  • 3. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 ABSTRACT • Almost 17.9 million people are losing their lives due to CardioVascular Disease, which have increased after the COVID-19 pandemic to 32% of total death throughout the world. • Technologies like MCGs help in detecting these diseases in early stage, but expensive, unfit for smaller clinics, time-consuming and sensitive to tangential causes • With AI entering and Machine Learning models, This study is aimed at building a potential machine learning model to predict heart disease in early stage .
  • 4. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 INTRODUCTION Cardiovascular disease (CVD) is a general term that describes a disease of the heart or blood vessels. Blood flow to the heart, brain or body can be reduced because of a: •blood clot (thrombosis) •build-up of fatty deposits inside an artery, leading to the artery hardening and narrowing (atherosclerosis)
  • 5. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 Types of CVD
  • 6. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 •Pre-existing cardiovascular disease (CVD) increases the morbidity and mortality of COVID-19 and is strongly associated with poor disease outcomes. •However, SARS-CoV-2 infection can also trigger acute and chronic cardiovascular disease. Acute cardiac complications include arrhythmia, myocarditis and heart failure, which are significantly associated with higher in-hospital mortality. The possible mechanisms by which SARS-CoV-2 causes this acute cardiac disease include direct damage caused by viral invasion of cardiomyocytes as well as indirect damage through systemic inflammation.
  • 7. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 •The Multifunction Cardiogram (MCG) is a kind of non- invasive diagnostic tool for measuring the health of a patient’s heart •The MCG uses a systems approach to modeling the heart and then comparing these models to a demographically appropriate risk-stratified database of similar patients using 166 indices with that database to aid both in the diagnosis and in predicting patient needs and outcomes. •Expensive, unfit for smaller clinics, time-consuming and sensitive to tangential causes
  • 8. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 •Researchers are employing artificial intelligence (AI) in an effort to mine new medical information that can be used by clinicians to better understand the symptoms of various diseases and, as a result, make more informed decisions for patients •The use of artificial intelligence (AI) and massive amounts of data in the prediction of CVD models is becoming increasingly common. •In view of the growing popularity of machine learning techniques, The traditional machine learning models that were tested and evaluated based on UCI Heart Disease dataset is used to having 14 columns and over 300 samples..
  • 9. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 METHODOLOGY Classification methods: Models such as Random forest (RF), decision tree classifier (DT), K- Nearest Neighbors(KNN), Support Vector Machine (SVM) are used
  • 10. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023
  • 11. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 Implementation Dataset: 300 entries of UCI Heart Disease dataset with 14 columns(data likeage,sex,cp,trestbp,chol,fbs) Implementation platform: Google collaboratory using PYTHON Packages used: Numpy Pandas Sci-kit
  • 12. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 EXPERIMENTAL ANALYSIS  The experiments focused on the performance of KNN using the datasets and features.  As the name says, a k neighbors classifier takes a data point and finds k other data points nearest to it in the vector space. In a supervised fashion, KNN creates clusters of the data samples having the same target value. Whenever a new value needs to be classified, it uses a distance metric to assign it to one of the classes. For heart disease detection, there are only two classes that KNN needs to build  For the first set of results the training dataset was divided at random into five folds, with training on four of the five folds, and testing on the remaining fold.  Models were trained on data set and achieved accuracy 91.5% with KNN Model.
  • 13. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 EXPERIMENTAL ANALYSIS  List the dataset Perform EDA
  • 14. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 EXPERIMENTAL ANALYSIS  Train the data on CP data values  The limited subset of the attributes we encoded and scaled. For instance, the chest pain data variable expanded into cp_0, cp_1, cp_2, and cp_3. This normalized and engineered dataset will be appropriate for training.
  • 15. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 EXPERIMENTAL ANALYSIS  Using the KNeighborsClassifier module we build a KNN model and iteratively tune the hyperparameter n_neighbors (number of neighbours to be checked for every data point).  Models were trained on data set and achieved accuracy 91.5% with KNN Model.
  • 16. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 EXPERIMENTAL ANALYSIS  The experiments focused on the performance of KNN using the datasets and features  Models were trained on data set and achieved accuracy 91.5% with KNN Model. Algorithm Accuracy Random Forest 86.8% KNN 91.8% Decision Tree 85.2% SVM 90.1%
  • 17. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 CONCLUSION To conclude, Early identification of heart disease of improved diagnosis and high-risk individuals using a prediction model can be recommended for a fatality rate reduction, and decision- making is improved for further treatment and prevention.
  • 18. National Symposium on High Performance Computing Applications using AI for Bioinformatics and Bio Medical Applications July 14-15,2023 Thankyou…!!