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BIOLOGY
                       CONCEPTS & CONNECTIONS
                                        Fourth Edition

Neil A. Campbell • Jane B. Reece • Lawrence G. Mitchell • Martha R. Taylor




                  CHAPTER 3
              The Molecules of Cells

                                   Modules 3.1 – 3.3

             From PowerPoint® Lectures for Biology: Concepts & Connections
                   Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Spider Silk: Stronger than Steel

• Life’s diversity results from the
  variety of molecules in cells
• A spider’s web-building skill
  depends on its DNA molecules
• DNA also determines the
  structure of silk proteins
        – These make a spiderweb
          strong and resilient


Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
• The capture strand contains a single coiled silk
   fiber coated with a sticky fluid

 • The coiled
   fiber
   unwinds to
   capture
   prey and
   then recoils
   rapidly

                                                                           Coiled fiber      Coating of
                                                                           of silk protein   capture strand


Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
INTRODUCTION TO ORGANIC COMPOUNDS
AND THEIR POLYMERS

• Life’s structural and functional diversity results
  from a great variety of molecules
• A relatively small number of structural patterns
  underlies life’s molecular diversity




Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
3.1 Life’s molecular diversity is based on the
    properties of carbon

• A carbon atom forms four covalent bonds
        – It can join with other carbon atoms to make
          chains or rings

                                         Structural               Ball-and-stick   Space-filling
                                          formula                     model          model




                                          Methane


                   The 4 single bonds of carbon point to the corners of a tetrahedron.
                                                                                                   Figure 3.1, top part

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
• Carbon skeletons vary in many ways

                                                          Ethane             Propane
                                                        Carbon skeletons vary in length.




                                                      Butane           Isobutane
                                               Skeletons may be unbranched or branched.




                                                1-Butene           2-Butene
                                 Skeletons may have double bonds, which can vary in location.




                                                      Cyclohexane          Benzene
                                                     Skeletons may be arranged in rings.    Figure 3.1, bottom part

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
3.2 Functional groups help determine the
    properties of organic compounds

• Functional groups are the groups of atoms that
  participate in chemical reactions
        – Hydroxyl groups are characteristic of alcohols

        – The carboxyl group acts as an acid




Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
Table 3.2
Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
3.3 Cells make a huge number of large molecules
    from a small set of small molecules

• Most of the large molecules in living things are
  macromolecules called polymers
        – Polymers are long chains of smaller molecular
          units called monomers
        – A huge number of different polymers can be
          made from a small number of monomers




Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
• Cells link monomers to form polymers by
   dehydration synthesis



                              1                    2                 3

                                        Short polymer                                       Unlinked monomer



                                                                     Removal of
                                                                     water molecule




                                               1                 2              3           4

                                                                           Longer polymer
 Figure 3.3A

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
• Polymers are broken down to monomers by the
   reverse process, hydrolysis




                                                    1                2         3       4



                                                                      Addition of
                                                                      water molecule




                                    1                2                 3
                                                                                           Coating of
                                                                                           capture strand
 Figure 3.3B

Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings

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Carbohydrates, Proteins, Lipids and Nucleic Acids

  • 1. BIOLOGY CONCEPTS & CONNECTIONS Fourth Edition Neil A. Campbell • Jane B. Reece • Lawrence G. Mitchell • Martha R. Taylor CHAPTER 3 The Molecules of Cells Modules 3.1 – 3.3 From PowerPoint® Lectures for Biology: Concepts & Connections Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 2. Spider Silk: Stronger than Steel • Life’s diversity results from the variety of molecules in cells • A spider’s web-building skill depends on its DNA molecules • DNA also determines the structure of silk proteins – These make a spiderweb strong and resilient Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 3. • The capture strand contains a single coiled silk fiber coated with a sticky fluid • The coiled fiber unwinds to capture prey and then recoils rapidly Coiled fiber Coating of of silk protein capture strand Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 4. INTRODUCTION TO ORGANIC COMPOUNDS AND THEIR POLYMERS • Life’s structural and functional diversity results from a great variety of molecules • A relatively small number of structural patterns underlies life’s molecular diversity Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 5. 3.1 Life’s molecular diversity is based on the properties of carbon • A carbon atom forms four covalent bonds – It can join with other carbon atoms to make chains or rings Structural Ball-and-stick Space-filling formula model model Methane The 4 single bonds of carbon point to the corners of a tetrahedron. Figure 3.1, top part Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 6. • Carbon skeletons vary in many ways Ethane Propane Carbon skeletons vary in length. Butane Isobutane Skeletons may be unbranched or branched. 1-Butene 2-Butene Skeletons may have double bonds, which can vary in location. Cyclohexane Benzene Skeletons may be arranged in rings. Figure 3.1, bottom part Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 7. 3.2 Functional groups help determine the properties of organic compounds • Functional groups are the groups of atoms that participate in chemical reactions – Hydroxyl groups are characteristic of alcohols – The carboxyl group acts as an acid Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 8. Table 3.2 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 9. 3.3 Cells make a huge number of large molecules from a small set of small molecules • Most of the large molecules in living things are macromolecules called polymers – Polymers are long chains of smaller molecular units called monomers – A huge number of different polymers can be made from a small number of monomers Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 10. • Cells link monomers to form polymers by dehydration synthesis 1 2 3 Short polymer Unlinked monomer Removal of water molecule 1 2 3 4 Longer polymer Figure 3.3A Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings
  • 11. • Polymers are broken down to monomers by the reverse process, hydrolysis 1 2 3 4 Addition of water molecule 1 2 3 Coating of capture strand Figure 3.3B Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings