15. CULTURE METHODS
Columbia agar with 5% sheep
blood and standard chocolate agar
Capnocytophaga sps
on trypticase soya
agar with horse
serum
Collagen or
hemoglobin
supplemented basal
medium for C.
gingivalis
16. INCIDENCE
C. g – 2.2%
Actinobacillus
actinomycetemcomitans, Porphyromonas
gingivalis, Capnocytophaga sputigena, and
Eikenella corrodens
In 1998- salari- 15.9%
Murray named only capnocytophaga
sputigena as prominent bacteria in chronic
periodontitis patients
25. ANTIBIOTIC THERAPY AND RESISTANCE
Capnocytophaga ochracea is susceptible to penicillin,
ampicillin, chloramphenicol, clindamycin, tetracycline,
third generation cephalosporins, quinolones and
metranidazole
Rummens et al. 1986 investigated the in vitro
activities of antimicrobial agents against
Capnocytophaga strains,
Foweraker et al. 1990 studied a strain that was
resistant to cephalosporins (MICs, ≥16 μg/ml).
Roscoe et al. 1992 characterized a membraneassociated low-efficiency cephalosporinase that
appears to be similar to the enzyme described by
Foweraker et al.
27. REFERENCES
Micheal G Newman, Henry H Takei, Perry R Klokkevold, Fermin A Carranza.
Clinical periodontology. 10th Ed.elsevier publishing
Spratt DA, Greenman J, Schaffer AG. Growth and hydrolytic enzyme production
of Capnocytophaga gingivalis on different protein substrates. Oral Microbiol
Immunol 1999: 14: 122-126
Yacoubi Amel; Djamila Bouziane; Makhrelouf Leila and Bensoltane
Advances in Medical and Dental Sciences, 3(3): 80-85, 2010. Microbiological
Study of Periodontitis in the West of Algeria
Sandholm L, Mahlberg K, Jousimies-Somer H. Phospholipase A1: a possible
virulence factor of Capnocytophaga ochracea. Oral Microbiol Immunol 1988: 3:
18-21.
Frandsen EVG, Reinholdt J, Kilian M; Immunoglobulin Al (IgAl) proteases from
Prevotella (Bacteroides) and Capnocytophaga species in relation to periodontal
disease. J Periodont Res 1991; 26; 297-299.
Dr Arora textbook of Microbiology
Betty A Forbes, Sahm Wiessfeld, Baileys and scotts, Diagnostic Microbiology.
Internet sources
