This document discusses the possibility of engineering empty space, known as the vacuum, for applications in spaceflight propulsion. It outlines that quantum theory predicts the vacuum contains residual background energy known as zero-point energy (ZPE). Recent experiments show the ZPE plays a role in large-scale phenomena and could potentially be harnessed. Several approaches are being investigated to extract energy from vacuum fluctuations, including exploiting the Casimir effect, sonoluminescence, resonant dielectric spheres, and micro-cavity techniques. If successful, this could provide a virtually unlimited and ubiquitous energy source for applications like space propulsion.