My lecture:
"Benefits and insights 2 years after implementation of NAVA and NIV NAVA as a standard of care…"
at the NAVA-symposium "A review of the experience and evidence so far..."
West Suffolk Hospital, Sept. 12th 2016
NHSScotland is constantly striving to increase efficiency and productivity whilst improving quality and effectiveness. In this session, delegates heard directly from colleagues who have changed their systems to deliver more effective care and how they value difference and variation within the NHS, using evidence to affect change. Delegates also had the opportunity to see some real examples from various settings across NHSScotland where evidence-based practice has been used to change systems and processes and how this has made a difference to patient outcomes, experience and value.
See more on the 2013 NHSScotland Event website http://www.nhsscotlandevent.com/resources/resources2013/resources
The document discusses the basics of neonatal ventilation. It explains that ventilation is used to provide oxygenation, remove carbon dioxide, and assist breathing in neonates. Key parameters discussed include peak inspiratory pressure, positive end expiratory pressure, compliance, resistance, tidal volume, and minute volume. Different modes of ventilation are also summarized, including their advantages and limitations. The importance of synchronization between the ventilator and patient's breathing is emphasized to reduce work of breathing and other complications.
Stroke Event 13 Sep - First morning presentationsCLAHRC-NDL
This document summarizes research on early supported discharge (ESD) services for stroke patients. The research aimed to evaluate whether the benefits of ESD seen in clinical trials are still evident in practice. The study compared outcomes for 135 patients receiving ESD services to 158 patients receiving usual care without ESD following a stroke. Results showed that the ESD group had significantly shorter hospital lengths of stay and were more knowledgeable about community support services. Statistical modeling also found that ESD patients were more likely to score higher on measures of independence at 6 weeks, 6 months and 12 months post-stroke. The research provides real-world evidence that ESD services continue to provide benefits for stroke rehabilitation compared to usual care without ESD support.
AAA 2016 networking day final presentationsMike Harris
The document summarizes the results and updates from the NHS AAA Screening Programme. Some key points:
- Almost 1.3 million men were invited for screening, with an uptake of 79.5%
- Nearly 13,000 abdominal aortic aneurysms (AAA) larger than 3cm were detected, with a prevalence of 1.3%
- Options to extend surveillance intervals to biennially were presented, which could result in cost savings of over £600,000 per invited cohort.
- Evidence was presented on the risk of AAA progression in men with subaneurysmal aortas between 2.6-2.9cm, supporting potential rescreening of these men after 5 years.
Lo mejor en cardiopatía isquémica e intervencionismo coronario
Dr. Ignacio Cruz González, Hospital Universitario de Salamanca
@icruzgonzalez
Lo mejor del Congreso AHA Anaheim 2017
16/11/17 14:00
http://aha17.secardiologia.es
#PostAHA17
This document discusses the regulatory pathway for MIGS devices in the United States. It outlines how the requirements for MIGS device approval through the PMA process have evolved over time based on learnings from early studies. Specifically, it notes that sample sizes, follow-up periods, clinical endpoints, and trial methodology have all increased in rigor. This includes moving primary endpoints from 12 to 24 months, requiring terminal washout periods, and measuring diurnal intraocular pressure. The document emphasizes that achieving level 1 clinical evidence for approval requires significant effort and collaboration between industry and the FDA over many years.
NHSScotland is constantly striving to increase efficiency and productivity whilst improving quality and effectiveness. In this session, delegates heard directly from colleagues who have changed their systems to deliver more effective care and how they value difference and variation within the NHS, using evidence to affect change. Delegates also had the opportunity to see some real examples from various settings across NHSScotland where evidence-based practice has been used to change systems and processes and how this has made a difference to patient outcomes, experience and value.
See more on the 2013 NHSScotland Event website http://www.nhsscotlandevent.com/resources/resources2013/resources
The document discusses the basics of neonatal ventilation. It explains that ventilation is used to provide oxygenation, remove carbon dioxide, and assist breathing in neonates. Key parameters discussed include peak inspiratory pressure, positive end expiratory pressure, compliance, resistance, tidal volume, and minute volume. Different modes of ventilation are also summarized, including their advantages and limitations. The importance of synchronization between the ventilator and patient's breathing is emphasized to reduce work of breathing and other complications.
Stroke Event 13 Sep - First morning presentationsCLAHRC-NDL
This document summarizes research on early supported discharge (ESD) services for stroke patients. The research aimed to evaluate whether the benefits of ESD seen in clinical trials are still evident in practice. The study compared outcomes for 135 patients receiving ESD services to 158 patients receiving usual care without ESD following a stroke. Results showed that the ESD group had significantly shorter hospital lengths of stay and were more knowledgeable about community support services. Statistical modeling also found that ESD patients were more likely to score higher on measures of independence at 6 weeks, 6 months and 12 months post-stroke. The research provides real-world evidence that ESD services continue to provide benefits for stroke rehabilitation compared to usual care without ESD support.
AAA 2016 networking day final presentationsMike Harris
The document summarizes the results and updates from the NHS AAA Screening Programme. Some key points:
- Almost 1.3 million men were invited for screening, with an uptake of 79.5%
- Nearly 13,000 abdominal aortic aneurysms (AAA) larger than 3cm were detected, with a prevalence of 1.3%
- Options to extend surveillance intervals to biennially were presented, which could result in cost savings of over £600,000 per invited cohort.
- Evidence was presented on the risk of AAA progression in men with subaneurysmal aortas between 2.6-2.9cm, supporting potential rescreening of these men after 5 years.
Lo mejor en cardiopatía isquémica e intervencionismo coronario
Dr. Ignacio Cruz González, Hospital Universitario de Salamanca
@icruzgonzalez
Lo mejor del Congreso AHA Anaheim 2017
16/11/17 14:00
http://aha17.secardiologia.es
#PostAHA17
This document discusses the regulatory pathway for MIGS devices in the United States. It outlines how the requirements for MIGS device approval through the PMA process have evolved over time based on learnings from early studies. Specifically, it notes that sample sizes, follow-up periods, clinical endpoints, and trial methodology have all increased in rigor. This includes moving primary endpoints from 12 to 24 months, requiring terminal washout periods, and measuring diurnal intraocular pressure. The document emphasizes that achieving level 1 clinical evidence for approval requires significant effort and collaboration between industry and the FDA over many years.
This document discusses the priorities and updates for the Fetal Anomaly Screening Programme (FASP) in 2017-2018. Key areas of focus include: implementing non-invasive prenatal testing (NIPT); improving data reporting for fetal anomaly scans and screening coverage; updating sonographer criteria and training resources; and developing new patient information materials about screening options. The overall aim is to support personalized, informed choices for women about screening and testing during pregnancy.
This study compared the efficacy of heated humidified high flow nasal cannula (HHHFNC) versus nasal continuous positive airway pressure (NCPAP) as the primary mode of respiratory support in preterm infants with mild to moderate respiratory distress. 88 preterm infants were included in the study and allocated non-randomly to receive either HHHFNC or NCPAP. The primary outcome of treatment failure within 72 hours was not significantly different between the two groups. However, moderate to severe nasal trauma occurred less frequently in infants receiving HHHFNC. While HHHFNC appears to be as effective as NCPAP with less nasal trauma, the study was limited by its non-randomized design and small sample size
This document summarizes hot topics in intensive care medicine that were presented by Steve Mathieu. It includes summaries of recent studies on ARDS treatments like HFOV, prone positioning, and statins. Guidelines on standards of care, tracheostomy procedures, blood transfusion, and AF management are reviewed. Recent studies on early versus late tracheostomy timing (TracMan) and HFOV versus conventional ventilation (OSCAR, OSCILLATE) in ARDS are summarized. The NAP4 study on airway complications in ICUs and operating rooms is also highlighted.
This document summarizes a ward round documentation audit conducted over 8 weeks. The results showed substandard documentation across several categories assessed. Discussion notes that poor documentation can negatively impact patient safety and care continuity. While electronic documentation may be ideal, pragmatic first steps include education, improving note access, utilizing ward round checklists, and addressing time pressures faced by junior doctors. The conclusion is that a multidisciplinary team approach is needed to implement stepwise improvements to documentation standards.
1. Post-operative pulmonary complications (PPCs) such as pneumonia, atelectasis, and acute lung injury are common after surgery, increasing mortality, length of hospital stay, and costs.
2. An audit was conducted of 102 patients undergoing major surgery to identify risk factors for PPCs and the rate of post-operative pneumonia. The overall PPC rate was 20.5% and the pneumonia rate was 14.7%.
3. High risk groups identified included those with ASA score of 3 or higher, pre-existing pulmonary disease, diabetes, smoking history, and surgeries over 180 minutes.
Thermo fischer scientific point of care testing for advanced patient stratifi...drucsamal
1) Thermo Fisher Scientific has partnered with Samsung to commercialize and co-develop innovative point-of-care testing solutions to meet customer needs and improve patient management.
2) Point-of-care cardiac troponin I testing by ambulance services in Scotland allows results to be available on or before arrival at the hospital for most transports, reducing time to treatment.
3) Copeptin, a surrogate marker for vasopressin, shows potential as a strategic complement to troponin testing for early rule-out of acute myocardial infarction when used together within 3 hours of presentation.
Lo mejor del Congreso ACC Chicago 2016
06/04/16 14:00 - 15:30h Casa del Corazón, Madrid
http://acc16.secardiologia.es
Lo mejor en insuficiencia cardiaca. #postACC16.
Dr. Alfonso Valle Muñoz, Hospital General Universitario Marina Alta, Denia (Alicante)
@ValleAlfonso
Fire and Ice - SNOMED makes a clinical impression - David BainbridgeHL7 New Zealand
This document discusses ambulance services in New Zealand and a new electronic patient report form (ePRF) system called CareMonX that is being implemented. It notes that there are about 600 ambulances nationally that respond to over 400,000 emergency calls per year. The current paper-based ambulance records are obsolete, illegible, and incomplete. CareMonX ePRF is an electronic clinical record system that will replace the paper forms and integrate with other healthcare providers using clinical standards. It will allow ambulance crews to capture patient assessment findings, vital signs, medications, and interventions using coded clinical terms like SNOMED CT which will improve data sharing and analysis.
Lisa Summers provided a national update on the NHS AAA Screening Programme. Key points included:
- Coverage and uptake rates for 2016/17 were 79.0% and 79.3% respectively.
- The programme is optimizing surveillance intervals and introducing an inequalities initiative to improve uptake by 10%.
- Further research is being done on men with subaneurysmal aortas to understand potential harms of surveillance.
- Issues raised from local programmes included improving GP endorsement of invitation letters and researching men who decline or do not attend screening.
Morag Armer then discussed emerging themes from QA visits, including governance, infrastructure, cohort and uptake data, test accuracy, and
A Critical Appraisal of Nephrology RCTs 2017Meguid Nahas
This document provides a summary and critical analysis of recent nephrology randomized controlled trials from 2015-2017. It discusses the SPRINT trial which found benefits of intensive blood pressure control but questions the validity of the findings given the increased risk of adverse events. It also summarizes the EMPA-REG trial on empaglifozin but notes the renal outcomes were from a post-hoc analysis so were hypothesis generating only. For the radiocontrast nephropathy study, it emphasizes the risk depends on patient comorbidities. Regarding the belatacept transplant trial, it argues the post-hoc analyses were underpowered and questions the statistical approach taken. Throughout, it stresses the importance of critically evaluating validity, risks, and
Safety and efficacy of using a single transradial MAC guiding catheter for coronary angiography and intervention in patients with ST-elevation myocardial infarction (RAPID)
This document appears to be a slide presentation about writing neuroimaging papers. It discusses impact factors of journals, who journal editors and reviewers are, what readers want, issues in neuroimaging papers, components of research, guidelines for reporting fMRI studies, ensuring reproducibility, and tips for writing different sections of a paper. The presentation provides information to authors on how to write transparent, rigorous neuroimaging papers that address reader needs and priorities for the field.
This document summarizes recent developments in airway management. It discusses new techniques for preoperative airway assessment including nasopharyngoscopy and use of ultrasound. It also discusses newer airway devices like videolaryngoscopes and second-generation supraglottic airways. Issues around techniques like cricoid pressure and extubation of difficult airways are analyzed. The importance of human factors, simulation-based training and dissemination of difficult airway information is emphasized to improve patient safety.
British Thoracic Society guidelines provide recommendations for oxygen use in healthcare settings. The guidelines aim to address issues such as a lack of understanding about appropriate oxygen use and patients receiving oxygen without prescriptions or within prescribed ranges. The guidelines recommend target oxygen saturation ranges for most patients of 94-98% and 88-92% for those at risk of hypercapnic respiratory failure. Lower limits are recommended to avoid potential harms from hypoxemia or hyperoxia.
Combining ultrasound non-destructive testing and bolting methods to improve r...Shaun West
This paper introduces the research undertaken to improve the reliability of bolted flange connections in structural engineering, with offshore wind turbines being used as an example. The current problem is that bolts are often over- or under-loaded, leading to premature failure. This shows that the existing loading methods cannot be relied on to balance the strains, which is the root cause of the bolting problem. This work highlights the importance of good asset management of bolted flange connections in the safety aspects of bolted flange connections.
Combining ultrasound non-destructive testing and bolting methods to improve r...Dominik Kujawski
This paper introduces the research undertaken to improve the reliability of bolted flange connections in structural engineering, with offshore wind turbines being used as an example. The current problem is that bolts are often over-or under-loaded, leading to premature failure. This shows that the existing loading methods cannot be relied on to balance the strains, which is the root cause of the bolting problem. This work highlights the importance of good asset management of bolted flange connections in the safety aspects of bolted flange connections.
The PRECOMBAT trial compared percutaneous coronary intervention (PCI) using sirolimus-eluting stents to coronary artery bypass grafting (CABG) for treating unprotected left main coronary artery disease over 1 and 2 year follow-ups. The trial found no significant differences in rates of death, heart attack, stroke, or other major cardiac events between PCI and CABG at 1 year. However, the rate of repeat revascularization of the target vessel was significantly lower with CABG than PCI at 2 years. The results met criteria for non-inferiority of PCI to CABG, but the study was underpowered with a wide margin so the findings are not considered definitive.
This document discusses the priorities and updates for the Fetal Anomaly Screening Programme (FASP) in 2017-2018. Key areas of focus include: implementing non-invasive prenatal testing (NIPT); improving data reporting for fetal anomaly scans and screening coverage; updating sonographer criteria and training resources; and developing new patient information materials about screening options. The overall aim is to support personalized, informed choices for women about screening and testing during pregnancy.
This study compared the efficacy of heated humidified high flow nasal cannula (HHHFNC) versus nasal continuous positive airway pressure (NCPAP) as the primary mode of respiratory support in preterm infants with mild to moderate respiratory distress. 88 preterm infants were included in the study and allocated non-randomly to receive either HHHFNC or NCPAP. The primary outcome of treatment failure within 72 hours was not significantly different between the two groups. However, moderate to severe nasal trauma occurred less frequently in infants receiving HHHFNC. While HHHFNC appears to be as effective as NCPAP with less nasal trauma, the study was limited by its non-randomized design and small sample size
This document summarizes hot topics in intensive care medicine that were presented by Steve Mathieu. It includes summaries of recent studies on ARDS treatments like HFOV, prone positioning, and statins. Guidelines on standards of care, tracheostomy procedures, blood transfusion, and AF management are reviewed. Recent studies on early versus late tracheostomy timing (TracMan) and HFOV versus conventional ventilation (OSCAR, OSCILLATE) in ARDS are summarized. The NAP4 study on airway complications in ICUs and operating rooms is also highlighted.
This document summarizes a ward round documentation audit conducted over 8 weeks. The results showed substandard documentation across several categories assessed. Discussion notes that poor documentation can negatively impact patient safety and care continuity. While electronic documentation may be ideal, pragmatic first steps include education, improving note access, utilizing ward round checklists, and addressing time pressures faced by junior doctors. The conclusion is that a multidisciplinary team approach is needed to implement stepwise improvements to documentation standards.
1. Post-operative pulmonary complications (PPCs) such as pneumonia, atelectasis, and acute lung injury are common after surgery, increasing mortality, length of hospital stay, and costs.
2. An audit was conducted of 102 patients undergoing major surgery to identify risk factors for PPCs and the rate of post-operative pneumonia. The overall PPC rate was 20.5% and the pneumonia rate was 14.7%.
3. High risk groups identified included those with ASA score of 3 or higher, pre-existing pulmonary disease, diabetes, smoking history, and surgeries over 180 minutes.
Thermo fischer scientific point of care testing for advanced patient stratifi...drucsamal
1) Thermo Fisher Scientific has partnered with Samsung to commercialize and co-develop innovative point-of-care testing solutions to meet customer needs and improve patient management.
2) Point-of-care cardiac troponin I testing by ambulance services in Scotland allows results to be available on or before arrival at the hospital for most transports, reducing time to treatment.
3) Copeptin, a surrogate marker for vasopressin, shows potential as a strategic complement to troponin testing for early rule-out of acute myocardial infarction when used together within 3 hours of presentation.
Lo mejor del Congreso ACC Chicago 2016
06/04/16 14:00 - 15:30h Casa del Corazón, Madrid
http://acc16.secardiologia.es
Lo mejor en insuficiencia cardiaca. #postACC16.
Dr. Alfonso Valle Muñoz, Hospital General Universitario Marina Alta, Denia (Alicante)
@ValleAlfonso
Fire and Ice - SNOMED makes a clinical impression - David BainbridgeHL7 New Zealand
This document discusses ambulance services in New Zealand and a new electronic patient report form (ePRF) system called CareMonX that is being implemented. It notes that there are about 600 ambulances nationally that respond to over 400,000 emergency calls per year. The current paper-based ambulance records are obsolete, illegible, and incomplete. CareMonX ePRF is an electronic clinical record system that will replace the paper forms and integrate with other healthcare providers using clinical standards. It will allow ambulance crews to capture patient assessment findings, vital signs, medications, and interventions using coded clinical terms like SNOMED CT which will improve data sharing and analysis.
Lisa Summers provided a national update on the NHS AAA Screening Programme. Key points included:
- Coverage and uptake rates for 2016/17 were 79.0% and 79.3% respectively.
- The programme is optimizing surveillance intervals and introducing an inequalities initiative to improve uptake by 10%.
- Further research is being done on men with subaneurysmal aortas to understand potential harms of surveillance.
- Issues raised from local programmes included improving GP endorsement of invitation letters and researching men who decline or do not attend screening.
Morag Armer then discussed emerging themes from QA visits, including governance, infrastructure, cohort and uptake data, test accuracy, and
A Critical Appraisal of Nephrology RCTs 2017Meguid Nahas
This document provides a summary and critical analysis of recent nephrology randomized controlled trials from 2015-2017. It discusses the SPRINT trial which found benefits of intensive blood pressure control but questions the validity of the findings given the increased risk of adverse events. It also summarizes the EMPA-REG trial on empaglifozin but notes the renal outcomes were from a post-hoc analysis so were hypothesis generating only. For the radiocontrast nephropathy study, it emphasizes the risk depends on patient comorbidities. Regarding the belatacept transplant trial, it argues the post-hoc analyses were underpowered and questions the statistical approach taken. Throughout, it stresses the importance of critically evaluating validity, risks, and
Safety and efficacy of using a single transradial MAC guiding catheter for coronary angiography and intervention in patients with ST-elevation myocardial infarction (RAPID)
This document appears to be a slide presentation about writing neuroimaging papers. It discusses impact factors of journals, who journal editors and reviewers are, what readers want, issues in neuroimaging papers, components of research, guidelines for reporting fMRI studies, ensuring reproducibility, and tips for writing different sections of a paper. The presentation provides information to authors on how to write transparent, rigorous neuroimaging papers that address reader needs and priorities for the field.
This document summarizes recent developments in airway management. It discusses new techniques for preoperative airway assessment including nasopharyngoscopy and use of ultrasound. It also discusses newer airway devices like videolaryngoscopes and second-generation supraglottic airways. Issues around techniques like cricoid pressure and extubation of difficult airways are analyzed. The importance of human factors, simulation-based training and dissemination of difficult airway information is emphasized to improve patient safety.
British Thoracic Society guidelines provide recommendations for oxygen use in healthcare settings. The guidelines aim to address issues such as a lack of understanding about appropriate oxygen use and patients receiving oxygen without prescriptions or within prescribed ranges. The guidelines recommend target oxygen saturation ranges for most patients of 94-98% and 88-92% for those at risk of hypercapnic respiratory failure. Lower limits are recommended to avoid potential harms from hypoxemia or hyperoxia.
Combining ultrasound non-destructive testing and bolting methods to improve r...Shaun West
This paper introduces the research undertaken to improve the reliability of bolted flange connections in structural engineering, with offshore wind turbines being used as an example. The current problem is that bolts are often over- or under-loaded, leading to premature failure. This shows that the existing loading methods cannot be relied on to balance the strains, which is the root cause of the bolting problem. This work highlights the importance of good asset management of bolted flange connections in the safety aspects of bolted flange connections.
Combining ultrasound non-destructive testing and bolting methods to improve r...Dominik Kujawski
This paper introduces the research undertaken to improve the reliability of bolted flange connections in structural engineering, with offshore wind turbines being used as an example. The current problem is that bolts are often over-or under-loaded, leading to premature failure. This shows that the existing loading methods cannot be relied on to balance the strains, which is the root cause of the bolting problem. This work highlights the importance of good asset management of bolted flange connections in the safety aspects of bolted flange connections.
The PRECOMBAT trial compared percutaneous coronary intervention (PCI) using sirolimus-eluting stents to coronary artery bypass grafting (CABG) for treating unprotected left main coronary artery disease over 1 and 2 year follow-ups. The trial found no significant differences in rates of death, heart attack, stroke, or other major cardiac events between PCI and CABG at 1 year. However, the rate of repeat revascularization of the target vessel was significantly lower with CABG than PCI at 2 years. The results met criteria for non-inferiority of PCI to CABG, but the study was underpowered with a wide margin so the findings are not considered definitive.
The Ultimate Guide in Setting Up Market Research System in Health-TechGokul Rangarajan
How to effectively start market research in the health tech industry by defining objectives, crafting problem statements, selecting methods, identifying data collection sources, and setting clear timelines. This guide covers all the preliminary steps needed to lay a strong foundation for your research.
"Market Research it too text-booky, I am in the market for a decade, I am living research book" this is what the founder I met on the event claimed, few of my colleagues rolled their eyes. Its true that one cannot over look the real life experience, but one cannot out beat structured gold mine of market research.
Many 0 to 1 startup founders often overlook market research, but this critical step can make or break a venture, especially in health tech.
But Why do they skip it?
Limited resources—time, money, and manpower—are common culprits.
"In fact, a survey by CB Insights found that 42% of startups fail due to no market need, which is like building a spaceship to Mars only to realise you forgot the fuel."
Sudharsan Srinivasan
Operational Partner Pitchworks VC Studio
Overconfidence in their product’s success leads founders to assume it will naturally find its market, especially in health tech where patient needs, entire system issues and regulatory requirements are as complex as trying to perform brain surgery with a butter knife. Additionally, the pressure to launch quickly and the belief in their own intuition further contribute to this oversight. Yet, thorough market research in health tech could be the key to transforming a startup's vision into a life-saving reality, instead of a medical mishap waiting to happen.
Example of Market Research working
Innovaccer, founded by Abhinav Shashank in 2014, focuses on improving healthcare delivery through data-driven insights and interoperability solutions. Before launching their platform, Innovaccer conducted extensive market research to understand the challenges faced by healthcare organizations and the potential for innovation in healthcare IT.
Identifying Pain Points: Innovaccer surveyed healthcare providers to understand their difficulties with data integration, care coordination, and patient engagement. They found widespread frustration with siloed systems and inefficient workflows.
Competitive Analysis: Analyzed competitors offering similar solutions in healthcare analytics and interoperability. Identified gaps in comprehensive data aggregation, real-time analytics, and actionable insights.
Regulatory Compliance: Ensured their platform complied with HIPAA and other healthcare data privacy regulations. This compliance was crucial to gaining trust from healthcare providers wary of data security issues.
Customer Validation: Conducted pilot programs with several healthcare organizations to validate the platform's effectiveness in improving care outcomes and operational efficiency. Gathered feedback to refine features and user interface.
The facial nerve, also known as cranial nerve VII, is one of the 12 cranial nerves originating from the brain. It's a mixed nerve, meaning it contains both sensory and motor fibres, and it plays a crucial role in controlling various facial muscles, as well as conveying sensory information from the taste buds on the anterior two-thirds of the tongue.
Research, Monitoring and Evaluation, in Public Healthaghedogodday
This is a presentation on the overview of the role of monitoring and evaluation in public health. It describes the various components and how a robust M&E system can possitively impact the results or effectiveness of a public health intervention.
India Home Healthcare Market: Driving Forces and Disruptive Trends [2029]Kumar Satyam
According to the TechSci Research report titled "India Home Healthcare Market - By Region, Competition, Forecast and Opportunities, 2029," the India home healthcare market is anticipated to grow at an impressive rate during the forecast period. This growth can be attributed to several factors, including the rising demand for managing health issues such as chronic diseases, post-operative care, elderly care, palliative care, and mental health. The growing preference for personalized healthcare among people is also a significant driver. Additionally, rapid advancements in science and technology, increasing healthcare costs, changes in food laws affecting label and product claims, a burgeoning aging population, and a rising interest in attaining wellness through diet are expected to escalate the growth of the India home healthcare market in the coming years.
Browse over XX market data Figures spread through 70 Pages and an in-depth TOC on "India Home Healthcare Market”
https://www.techsciresearch.com/report/india-home-healthcare-market/15508.html
R3 Stem Cell Therapy: A New Hope for Women with Ovarian FailureR3 Stem Cell
Discover the groundbreaking advancements in stem cell therapy by R3 Stem Cell, offering new hope for women with ovarian failure. This innovative treatment aims to restore ovarian function, improve fertility, and enhance overall well-being, revolutionizing reproductive health for women worldwide.
Sectional dentures for microstomia patients.pptxSatvikaPrasad
Microstomia, characterized by an abnormally small oral aperture, presents significant challenges in prosthodontic treatment, including limited access for examination, difficulties in impression making, and challenges with prosthesis insertion and removal. To manage these issues, customized impression techniques using sectional trays and elastomeric materials are employed. Prostheses may be designed in segments or with flexible materials to facilitate handling. Minimally invasive procedures and the use of digital technologies can enhance patient comfort. Education and training for patients on prosthesis care and maintenance are crucial for compliance. Regular follow-up and a multidisciplinary approach, involving collaboration with other specialists, ensure comprehensive care and improved quality of life for microstomia patients.
Joker Wigs has been a one-stop-shop for hair products for over 26 years. We provide high-quality hair wigs, hair extensions, hair toppers, hair patch, and more for both men and women.
nursing management of patient with Empyema pptblessyjannu21
prepared by Prof. BLESSY THOMAS, SPN
Empyema is a disease of respiratory system It is defines as the accumulation of thick, purulent fluid within the pleural space, often with fibrin development.
Empyema is also called pyothorax or purulent pleuritis.
It’s a condition in which pus gathers in the area between the lungs and the inner surface of the chest wall. This area is known as the pleural space.
Pus is a fluid that’s filled with immune cells, dead cells, and bacteria.
Pus in the pleural space can’t be coughed out. Instead, it needs to be drained by a needle or surgery.
Empyema usually develops after pneumonia, which is an infection of the lung tissue. it is mainly caused due in infectious micro-organisms. It can be treated with medications and other measures.
English Drug and Alcohol Commissioners June 2024.pptxMatSouthwell1
Presentation made by Mat Southwell to the Harm Reduction Working Group of the English Drug and Alcohol Commissioners. Discuss stimulants, OAMT, NSP coverage and community-led approach to DCRs. Focussing on active drug user perspectives and interests
English Drug and Alcohol Commissioners June 2024.pptx
CAMBRIDGE SEPTEMBER-12-09
1. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 1
Benefits and insights 2 years after implementation
of NAVA and NIV NAVA as a standard of care…
Torben Steensgaard Andersen, MD, MHIT, Consultant
2. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 2
Conflict of interest
Maquet Critical Care has defrayed my expenses of hotels, flights etc for this lecture
Maquet Critical Care has granted the Dept. of Anaesthesiology at Vejle Hospital for time
used for hospital record reviews in connection with the study
3. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 3
• PRESENTATION
• IMPLEMENTATION STRATEGIES (what we did)
• RESULTS (if any !!)
• A FEW CASES
• WHAT’S NEXT IN NAVA? or
• If I could wish
5. Vejle Hospital
- a part of Lillebaelt Hospital
NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 5
6. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 6
Facts and Figures
KEY FIGURES
• App. 62,000 inpatients with a mean length of stay of 3,7 days
• 463,800 outpatient attendances
• App. 700 beds
• App. 4,500 members of staff (full time)
• 2 ICUs with a total of 24 beds
7. Vejle Hospital
Specialized in diagnostics, treatment and care of cancer
KEY FIGURES
22.000 ward patients
250.000 outpatients
21.000 visits in ER
NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 7
8. Key specialities
• Cardiology
• General Surgery
• Haematology
• Oncology
• Orthopedic surgery
• Neurology
• Ear, Nose and Throat Surgery
NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 8
12. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 12
• PRESENTATION
• IMPLEMENTATION STRATEGIES (what we did)
• RESULTS (if any !!)
• A FEW CASES
• WHAT’S NEXT IN NAVA? or
• If I could wish
13. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 13
• IMPLEMENTATION
”Step-by-step”
The goal is known, but the order
established during implementation
20. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 20
HOW DID WE EDUCATE?
• 2-3 hours theoretical education for all staff
• Constantly bed-side training for juniors and nurses
• A ”Weekly Focus” patient
• Repeatedly discussed on weekly staffmeetings
21. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 21
Since April 1st 2014:
ALL patients with respiratory insufficiency shall have an Edi
catheter
EXCEPT
Patients who are expected to be without need for support
within 12-24 hours
Patients with known hiatal/esophageal hernia
Patients with known bleeding disorders in oesophagus
Patients who are treated with therapeutic hypothermia
22. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 22
PHILOSOPHY SINCE 2014:
• Monitor respiratory capacity with Edi
• Ventilate with NAVA if possible
(invasive or non-invasive)
23. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 23
• PRESENTATION
• IMPLEMENTATION STRATEGIES (what we did)
• RESULTS (if any !!)
• A FEW CASES
• WHAT’S NEXT IN NAVA? or
• If I could wish
25. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 25
1 8 m o n t h s
1 8 m o n t h s
versus
A
B
NO NAVA (n = 114) NAVA (n = 43)
NO NAVA (n = 86) NAVA (n = 68)
26. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 26
A Bversus
No differences in:
• Speciality (medical/surgical/neurology/cardiology/haematology)
• Gender
• Age
• Diagnoses
• Reintubation
• BMI
• Initial bloodgases
27. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 27
NO NAVA (n = 114) NAVA (n = 43)
Time ( AVG hours)
Mechanical ventilation 31 112
Sedation with remifentanil 19 85
Use of norepinephrine 24 33
A
NO NAVA (n = 86) NAVA (n = 68)
23 76
21 49
23 44
B
Mortality n (%) n (%)
Dead in the ICU 20 (18) 13 (30)
Dead in 30 days 20 (18) 6 (14)
Dead in 90 days 8 (7) 6 (14)
Alive at 90 days 66 (58) 18 (42)
n (%) n (%)
10 (12) 19 (28)
12 (14) 15 (22)
3 (3) 1 (1)
61 (71) 33 (48)
Scores
APACHE II 23 25
SAPS II 45 51
21 27
41 49
28. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 29
PATIENT CHARACTERISTICS COMPARED FOR 3 GROUPS
COMBINING THE 2 TIME PERIODS:
• PATIENTS WITHOUT ANY NAVA-TREATMENT
• PATIENTS RECEIVING NAVA FOR MORE THAN 50% OF VENTILATOR TIME
• PATIENTS RECEIVING NAVA FOR LESS THAN 50% OF VENTILATOR TIME
29. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 30
NO NAVA (n = 200) NAVA < 50% (n =51) NAVA ≥ 50% (n =60)
Time (hours AVG)
Mechanical ventilation 42 79 79
Sedation with remifentanil 20 71 65
Use of norepinephrine 24 36 42
p
< 0.001
< 0.001
0.02
Mortality
Dead in the ICU 30 (15%) 19 (37%) 13 (22%)
Dead in 30 days 32 6 15
Dead in 90 days 11 2 5
Alive at 90 days 127 24 27
0.007
ns
ns
ns
Scores
APACHE II 22 28 25
SAPS II 43 51 49
< 0.001
< 0.01
LOS ICU 68 134 139 < 0.001
30. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 31
STAFF EXPERIENCES - A QUESTIONNAIRE
52 nurses and 18 physicians completed the survey
Majority > 10 years’ of experience as a professional
31. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 32
STAFF EXPERIENCES - A QUESTIONNAIRE
RESULTS
Advantages
• Faster correction of respiratory insufficiency (58%)
• Monitoring of respiratory capacity (42%)
• Decreased ventilator time (29%)
• Increased patient comfort (80%)
• Increased patient involvement (33%)
• Other (8%)
Disadvantages
• Applying a particular nasogastric tube (40%)
• Need for training in the NAVA modus (35%)
• Troublesome to adjust correctly (15%)
• Demands more in regard to collaboration with the patient (25%)
• Other (25%)
• (this included the heaviness of the NG tube and short cabling)
32. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 33
STAFF EXPERIENCES - A QUESTIONNAIRE
RESULTS
84% found to a high or very high degree that NAVA is an excellent
therapy option
79% experienced no barriers in regard to NAVA therapy
Those experiencing barriers found that the main ones were
• Lack of experience for both nurses and physicians
• Difficulties interpreting the alarms
• The lack of control of most respiratory parameters
33. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 34
STAFF EXPERIENCES - semi-structured interviews
3 senior and 1 junior physician
2 senior nurses and 1 junior nurse
Advantages of NAVA
• Increased patient comfort
• Increased synchrony with the ventilator
• Improved opportunities for monitoring patient respiratory performance
The implementation
• The implementation had overall been very succesful
• With a united commitment from physicians and nurses to move forward with
NAVA the implementation proces accelerated
34. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 35
STAFF EXPERIENCES - semi-structured interviews
The main barriers
• Lack of knowledge
• Uncertainty about NAVA
• Lack of courage to skip the control over the patients ventilation
• The time and effort needed to find the right setting for the individual patient
• (the triangle between patient, physician and ventilator)
Suggestions for improving implementation
• Educating more ”Super-NAVA-nurses and -doctors”
• Ensure expert knowlegde in the ICU 24/7
• Structured peer-to-peer training in practice
• More education to especially senior physicians used to traditional respiratory
therapy (!)
35. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 36
• PRESENTATION
• IMPLEMENTATION STRATEGIES (what we did)
• RESULTS (if any !!)
• A FEW CASES
• WHAT’S NEXT IN NAVA? or
• If I could wish
36. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 37
Female
70 years old
COPD - now pneumonia with hypoxia and hypercapnia. pH 7.19
Initially and for 18 hours ventilated with NIV-PS/PC without
correcting her blodgasses
Placing af Edi catheter
CASE I
40. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 41
Female
70 years old
COPD - now pneumonia with hypoxia and hypercapnia. pH 7.19
Initially and for 18 hours ventilated with NIV-PS/PC without
correcting her blodgasses
Placing af NAVA catheter.
After 8 minutes there is a perfect patient-ventilator synchronisation
followed by rapid correction of blodgasses and normalization of pH.
41. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 42
Male
60 years old
COPD. Skizophrenia. Found unconscious. pH 7.29 PaCO2 12 kPa.
Initially ventilated with NIV-PS for several hours without correction
of bloodgases
Placing af Edi catheter
CASE II
Demonstrating asynchrony
45. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 46
Male
60 years old
COPD. Skizophrenia. Found unconscious. pH 7.29. PaCO2 12 kPa
Initially ventilated with NIV-PS
Asynchrony
Placing af NAVA catheter
Immediate synchronisation.
Correcting pH in 1 hour to 7.34 and PaCO2 9 kPa
46. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 47
Male 57 yo Weight 120 kg (BMI 39)
Skizophrenia and COPD.
Found laying on the floor - probably for the last 24 hours.
Severe pneumonia and septic shock
CASE III
50. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 51
FiO2 from 0.6 to 0.35
PaO2/FiO2 from170 to 225
pH from 7.18 to 7.43
PaCO2 from 8.7 to 5.4
51. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 52
Male 57 yo Weight 120 kg (BMI 39)
Skizophrenia and COPD.
Found laying on the floor - probably for the last 24 hours. Severe
pneumonia and septic shock
Rapid correction of blood gases, reduction of FiO2, improvement of
P/F-fraction and ready for extubation or NIV
52. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 53
Male 80 yo Previously fit and healthy
Subdural hematoma Evacuated Pneumonia
Respiratory insufficiency Ventilator weaning
CASE IV
54. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 55
Part of procedure - given 40 mg propofol at 13.40
Note the reduction in Edi peak from 11 to 2.6 and the patients
ability to breath with very little diaphragmatic effort ….
..perfectly breathing with PS/CPAP ?
55. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 56
Male 80 yo Previously fit and healthy
Subdural hematoma Evacuated Pneumonia
Respiratory insufficiency Ventilator weaning
Think about:
Spontaneously breathing patient but without diaphragmatic effort
Monitor your sedation by means of the Edi-signal
56. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 57
CASE V
Male 72 yo
Known with diabetes, aortic stenosis, cerebral shunt(hydrocephalus).
Intracerebral hemorrhage -> Evacuated -> Pneumonia
Respiratory insufficiency
Transferred from University Hospital to our ICU at day 6 with a report
saying that:
“The patient is unable to breath sufficiently when we have tried to
let him breath spontaneously”
58. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 59
• Placing a Edi catheter
• Changing the mode to PC/PS
• “Starving” the patient by reducing Pressure Control
59. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 60
Primary result:
Spontaneously breathing without any work from the diaphragm
63. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 64
Male 72 yo
Known with diabetes, aortic stenosis, cerebral shunt(hydrocephalus).
Intracerebral hemorrhage -> Evacuated -> Pneumonia
Respiratory insufficiency
Transferred from University Hospital to our ICU at day 6 with a report
saying that he couldn’t breath sufficiently when they tried to let him
breath spontaneously
Think about:
Hyperventilated patients often don’t breath spontaneously.
Monitor your ventilation by means of the Edi-signal
CASE V
64. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 65
CASE VI
Male 73 yo
Previously fit and healthy Was still working as a teacher
Sudden aphasia and lack of motor control. Rushed to thrombolytic
therapy but proved ineffective.
Thrombectomy was attempted but was abandoned due to bilateral
stenosis in aa. vertebrae
65. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 66
9 days after insult and tracheostomy transferred to center for neural
rehabilitation and ventilator weaning.
7 days after the transferral without need for ventilator in daytime
and ventilator was discontinued.
The following night cardiac arrest probably due to ventilatory
arrest/insufficiency and hypoxaemia.
2 weeks later transferred to Vejle ICU - still in need of respiratory
support at a low level (PS 11 cmH2O, PEEP 7 cmH2O, FiO2 0.28)
66. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 67
An Edi catheter was applied and detected normal diaphragmatic
activity in the awake patient.
67. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 68
Normal diaphragmatic activity while the patient is awake -
ventilated with PS/CPAP
68. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 69
During sleep however, all innervation of the diaphragm ceased,
testifying that the patient's respiratory drive was exclusively relying
on voluntary muscle contractions.
69. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 70
An MRI was performed, which revealed sequelae after a massive
ischemic event near the brainstem of recent date confirming the
suspicion evoked during ventilator therapy.
70. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 71
Male 73 yo
Previously fit and healthy Was still working as a teacher
Sudden aphasia and lack of motor control. Rushed to thrombolytic
therapy but proved ineffective.
Thrombectomy was attempted but was abandoned due to bilateral
stenosis in aa. vertebrae
The Edi-signal as a diagnostic tool
Detection of Acquired Central Hypoventilation Syndrome (Ondine’s
Curse) in an elderly male by means of monitoring with neurally
adjusted ventilatory assist.
CASE VI
71. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 72
A few keypoints:
• Implement as a ”Big Bang”
• Be sure that the staff is (very) well educated
• Be sure you have NAVA-expertise 24/7/365
• Speed up the implementation by a united commitment from physicians and nurses
• More education to especially senior physicians used to traditional respiratory
therapy!
• If you need proving your results
• Design a prospective trial
• Use NAVA for
• Correcting asynchrony
• Monitoring sedation
• Rapid correction of ventilatory parameters
• Monitoring your patients diaphragmatic activity
• NAVA is
• ”Driving a car by looking out the front window instead of by looking in the rear
mirror”
• A supplementary diagnostic tool in neurological diseases such as ”Ondine’s Curse,
ALS, critical illness polyneuropathy
72. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 73
Some other insights
• For both nurses and doctor has this high level
technology changed focus to basal, human
physiology
• Personalized and spontaneous breathing is alpha
and omega for better comfort, reduced ventilator
days and very fast weaning
73. NAVA-Symposium Cambridge 2016-09-12 Torben Steensgaard Andersen 74
• PRESENTATION
• IMPLEMENTATION STRATEGIES (what we did)
• RESULTS (if any !!)
• A FEW CASES
• WHAT’S NEXT IN NAVA? or
• If I could wish