Blistigel is a medical device introduced by the Institut Nord-Sud de Cooperation Biopharmaceutique (INSCB) that aims to address problems with preparing and administering crushed tablets to patients with swallowing difficulties. It consists of a double compartment sachet that allows crushed tablets to be blended with an edible gel carrier. This provides easier, faster, and safer preparation of crushed medications while ensuring traceability of treatment and compliance through single-use, pre-measured dosing in a portable format. Blistigel offers a simplified solution to common issues experienced with traditional methods of administering crushed tablets to patients.

1. I.N.S.C.B.
L’INSTITUT NORD-SUD de COOPERATION BIOPHARMACEUTIQUE
INTRODUCES
BLISTIGEL
An innovative medical device for the
administration of oral pharmaceuticals
A NEW STEP IN THE ADMINISTRATION
OF CRUSHED TABLETS
 Easier and faster preparation
 Precise dose administration
 1 Single sachet per patient
 Confined and safe crushing
 Traceability of treatment

2. UNDER DOSING
(INCOMPLETE TREATMENT ADMINISTRATION)
VARIABILITY OF THE PERIOD
BETWEEN PREPARATION AND
ADMINISTRATION
OUTDOORS STORAGE
BETWEEN PREPARATION AND ADMINISTRATION
DRUG – CARRIER MEDIA INTERACTIONS
LACK OF TRACEABILITY
(identifications treatments / patients)
PROFESSIONNAL ALLERGIC ACCIDENTS...
Swallowing Troubles or Dysphagia,
Concern especially
geriatrics, pediatrics,
psycho-behavioral therapeutics,
and some pathologies of the
Ear Nose and Throat Sphere
For 100% of the patients ,
Their tablets are systematically crushed
And this three times per day…
They are then administered
using a medium carrier
(gelled water, food, drinks…)
BLISTIGEL
IS A TABLETS’ ADMINISTRATION DEVICE
INTENDED FOR PATIENTS SUFFERING FROM
SWALLOWING TROUBLES
DES COMPRIMES DESTINE AUX PATIENTS
PRESENTANT DES TROUBLES DE LA DEGLUTITION
PROBLEMS LINKED WITH THE
PREPARATION & ADMINISTRATION
OF CRUSHED TABLETS...
… LEAD TO POTENTIAL RISKS
FOR THE PATIENT
AND THE CAREGIVER STAFF

3. It’s a 2 in 1 :
1 single device is used for the preparation and
administration of the médicines
Compliance of the treatment
o No substance loss during blending
o Whole product administered thanks to low volume of carrier medium
o No false food drive risk due to the alimentary gel viscosity
o Direct administration of the treament from the device
o Adaptation to patient’s taste thanks to multiple flavors
o No outdoors storage of the crushed powders
Safety
o Single use device
o EIdentification label allowing traceability
o Limited chemical Interactions with the neutral alimentary carrier gel
o Absence of risk of inhalation of crushed powder
o
Simplified handling
o 1 single package for both medicines and alimentary carrier gel
o Reduced time of preparation
o Tablets crushed directly in the device
BLISTIGEL IS THE SOLUTION
A double compartment Sachet allowing the blending of
the crushed tablets with an alimentary gel

4. Use protocol
I – Introduce the tablets inside
the empty compartment
of the sachet
II- 1 Fold the upper compartment
II- 2 Close it with the sticky
repositionable strip
III – The device is hermetically closed.
IV – Crush the tablets using a tablet mill of your choice
(presses, hammers, pestle…)

5. 1 2
V-1 Apply manual pressure from bottom
to top until the frangible seal breaks,
allowing the mixture of the crushed
powder with the alimentary gel
V-2 Knead the mixture
until it becomes homogeneous
VI-1 Open the sachet by pulling the
repositionable strip
VI-2 The mixture is then ready to be
administered to the patient
« PATIENT »
Identification label
STUCK ON THE GEL
COMPARTMENT OF THE
SACHET TO GUARANTEE
TRACEABILITY
Indicates :
- SURNAME
- NAME
- DATE OF BIRTH
- ROOM NUMBER
- etc...

6. IS A TYPE 1 MEDICAL DEVICE
with EC conformity marking
TECHNOLOGY PATENTED
BY THE INSCB
AVAILABLE FOR LICENSING
CONTACT :
INSCB
CNRS – Incubateur
1919 Route de Mende
34293 Montpellier Cedex 5
France
Tel : +33 (0) 672 042 888
E-mail : contact@inscb.org
I.N.S.C.B. - CNRS / Incubateur 1919 route de Mende 34293 Montpellier Cedex 5 - France
SIRET : 800 455 545 00015 code APE : 7490B
BLISTIGEL
A two in one sachet allowing the
administration of crushed tablets