Nomenclature of bridge
head heterocycles
Dr Taj Khan
Dept. of Pharmaceutical Chemistry, OCP,
Sanpada, New Mumbai.
Two carbons forming each bridge will always be “cis” to each other
Both hydrogens are on the same side
Both “bridgehead” positions are on the same C, so cant use “bicyclo” nomenclature as before-
but the process is very similar.
simply substitute “spiro” for “bicyclo” , insert the two bridge lengths, and place the suffix as before.

Bridge head system momenclature

  • 1.
    Nomenclature of bridge headheterocycles Dr Taj Khan Dept. of Pharmaceutical Chemistry, OCP, Sanpada, New Mumbai.
  • 3.
    Two carbons formingeach bridge will always be “cis” to each other Both hydrogens are on the same side
  • 7.
    Both “bridgehead” positionsare on the same C, so cant use “bicyclo” nomenclature as before- but the process is very similar. simply substitute “spiro” for “bicyclo” , insert the two bridge lengths, and place the suffix as before.