The Royal Botanical Expedition to New Granada took place from 1783 to 1816 in territories that now make up several South American countries. The expedition was led by José Celestino Mutis, a Spanish botanist, and aimed to catalog the rich plant life of the region. Over 25 years, Mutis and his team explored over 8,000 square kilometers, discovering around 6,000 new plant species. Their work resulted in detailed drawings, descriptions and classifications of plants, contributing significantly to the field of botany.