This document describes a web-based registry that aims to provide guidance for researchers, developers, and curators on selecting content standards and databases. There are almost 600 content standards in the life sciences. The registry will allow users to search for, filter, submit, and view information on standards and databases. It will link standards to databases that implement them and provide visualizations of standard formats and terminologies. The goal is to help stakeholders make informed decisions by providing a curated, searchable registry of standards and database information. An advisory board and working group will oversee the registry's development and operations.