1. Retroviruses like HIV use an enzyme called reverse transcriptase to produce DNA copies of their RNA genomes so they can integrate into the host cell's DNA. 2. Reverse transcriptase is also used in molecular biology to make DNA copies of mRNA transcripts in order to study and manipulate genes. 3. Gene therapy aims to treat genetic diseases by inserting normal genes into patients' cells, either to complement recessive alleles or override dominant disease-causing alleles. However, it carries risks like harming patients or diseases developing.

2. They use the enzyme, ______________________ for production of _____ from ______.

3. Reverse Transcriptase is used after the Retrovirus has entered the host cell used to make a _____________ of their _______________.

5. _____________________ DNA copies of the mRNA are made using ___________________________________ called __________.

6. DNA polymerase is used to convert the ___________________ DNA into ____________________ DNA produces ______________________________ into another organism.

8. IF disease caused by a recessive allele… __________________________________ inserted into _____________________.

10. Body cells altered do not develop into _______________.

11. Often ______________________ of cells will be altered.

12. Genetic disease may be ______________________________________

13. ______________________ Offspring

14. Germ-line therapy:

15. Sperm or egg cells treated (or ______________________ to produce sperm or egg cells)

16. Disease will ______________________ offspring