The document discusses the dark and unethical practices of the pharmaceutical industry. It notes that corruption is endemic at every step of the pharmaceutical business according to the WHO. Unethical marketing practices are used to increase profits by raising customer demand. Doctors and pharmacists face conflicts of interest as their earnings depend on drug sales. Technical solutions have been proposed like reforming drug approval and increasing regulatory independence, but the industry opposes changes due to its political influence.

1. A dark side of pharmaceutical industry

3.  Big pharma looms like a dementor over our
medical system.
 It effectively eliminates lights and despair.
There is no doubt in my mind that big
pharma harms millions of peoples every year.
 Many of whom become permanently ill and
die prematurely as a result of their drug use.

4.  Corruption and unethical practices are
endemic at every step of the pharmaceutical
business, according to WHO. One only has to
turn to the seemingly on going saga of
GlaxoSmithKline to know this. Their case
seems to be wide spread across globe.
 It Seems that GSK is a leader in pharma fraud
and wrong doing. But other industry big
shots are closed behind.

5.  Corruption in pharmaceutical supply chain can
takes many forms:
 Product can be diverted or stolen at various
points in distribution system.
 Clinical trials may be conducted without proper
regulatory approval.
 Product may be un registered with incorrect or
insufficient information.
 Demand for favours may be placed on supplier as
condition for prescribing medicine.
 Counterfeit or other forms of sub standard
medicines may be allowed to circulate.

7.  The fundamental aim of corporate drug
marketing practices is to raise profit by
increasing customers demand.
 Mainly pharmacist who are retail pharmacies
face a stern prospective conflict of interest.
On one side of picture they are professional
,predictable to be inform about medicine and
to distribute them in ethical manner being
responsible professional and citizen.

8.  On the other hand ,their earning ,incentives,
bonuses and perks depend on the sale of
medicinal products.
 An important perspective is that meeting of
sales representative and doctors influences
doctors prescription show that companies
websites providing information regarding
drugs only concentrate on their benefits and
hide side effects of medicines.
.

9.  The pharmaceutical company applies both “push
and pull” strategies for the promotion of their
products.
 The pharmaceutical industry's unethical practices
are supported by doctors and other entities, they
have become greedy and selfish because the
pharmaceutical company sponsored most of the
conferences of doctors and offers them the gifts.
 Nowadays pharma industries focus on unethical
marketing practices for their drug promotion
simply called birth of corruption starting from
launching new drugs and authorizing the price

10.  Determination of medicines, drug promotion
and sale and procurements which a direct
impact on human health and it is all being
done for sake of increment in market share
so this system need to be assessed carefully
for effective working of health system.

11.  Public advertising gets increasingly powerful
using aggressive direct to consumer
marketing, payment to celebrities for
appearing on TV show and telling about their
illness and cures, and sophisticated getting of
consumer groups that will then effectively
lobby insurers and regulator for industry
causes.

12.  Many scholars have proposed technical
solution to the problem posed by
pharmaceutical companies .
 Voluntary ethical guideline have been shown
to fail.
 A reform in drug approval should include that
manufactures should produce not to evaluate
new drugs and the comparison should be
with existing drugs and not with placebo.

13.  The independence of regulatory bodies should be
strengthen and patent protection should be
reduced. The industry should be excluded from
medical education and direct to consumer
advertising totally banned.
 The industry oppose these changes and with its
current power and ties to political forces, a
significant move towards correct direction is
unlikely .
 Awareness ,research and public education about
problem are necessary to foment sufficient
political will for change.