This document provides an overview of big history from the origins of humans in Africa to modern world trade. It summarizes theories about human migration patterns out of Africa based on genetic and archaeological evidence. Major points of discussion include the catastrophes caused by volcanic eruptions in the 6th century CE, Jared Diamond's theory about advantages of certain civilizations due to geography and domesticable plants/animals, and the massive exchange of people, goods and diseases between the old and new worlds beginning in the 15th century.