This document discusses a new research agenda for Wikimedia to address challenges and opportunities arising from the growth of human and machine knowledge. It outlines areas for research including: preserving transparent sourcing of information as answers become readily available from search; breaking down long-form articles into structured data and fragments for new forms of consumption; and distributing content in ways that route attention back to Wikimedia instead of intermediating it. The agenda proposes evaluating systems that address these areas to help Wikimedia continue supporting open knowledge curation in the age of machines.