Dr Manasi Baranwal
Fortis Escorts Heart Institute
ECHO: BASIC VIEW AND FINDING IN
NORMAL TTE & TEE
2
Echo is something you experience all the time. If you shout
into a well, the echo comes back a moment later. The echo
occurs because some of the sound waves in your shout reflect
off a surface (either the water at the bottom of the well or the
wall on the far side) and travel back to your ears. A similar
principle applies in cardiac ultrasound.
ECHO
HISTORY
Christian Andreas Doppler - Austrian
mathematician and physicist. (1803-
1853)
He is celebrated for his principle –
known as the Doppler effect (1842) –
that the observed frequency of a wave
depends on the relative speed of the
source and the observer.
He used this concept to explain the
colour of binary stars
PIEZOELECTRIC EFFECT
The ability to create ultrasonic waves
came in 1880 with the discovery of
PEIZOELECTRICITY by Curie and Curie.
Jacques Curie (1855 – 1941) was a French
physicist ,Along with his younger
brother, Pierre curie
The brothers Curie thought there would be a
direct correlation between the potential
generated by temperature changes and the
mechanical strain that gave rise to
piezoelectricity
PIEZOELECTRIC EFFECT
HISTORY
Carl Hellmuth Hertz - German physicist
known for involved in the development of
inkjet technology and ultrasound technology.
Carl Hellmuth Hertz
Inge Gudmar Edler (1911 – 2001)
Swedish cardiologist, who in collaboration
with Carl Hellmuth Hertz developed medical
ultrasonography and echocardiography.
Edler and Hertz shared the 1977
Lasker-DeBakey
Clinical Medical Research Award for this
achievement
Inge Gudmar Edler
Dr. Helmut Hertz of Sweden in 1953 obtained a commercial
ultrasonoscope, which was being used for nondestructive testing. He
then collaborated with Dr. Inge Edler who was a practicing cardiologist in
Sweden. The two of them began to use this commercial ultrasonoscope
to examine the heart. This collaboration is commonly accepted as the
beginning of clinical echocardiography as we know it today.
Edler finally established the characteristic
motion pattern for the anterior leaflet of
the mitral valve.
He compared the shape of the fast moving
echoes in patients with enlarged hearts due to
mitral stenosis during cardiac operations, and
found empirically the shape correlated well
with the severity of the stenosis.
By early 1955, Edler had so much evidence of
this relationship that he relied on ultrasound
alone for the diagnosis of mitral stenosis.
HISTORY
Generation Of An Ultrasound Image
Echocardiography (echo or
echocardiogram) is a type of
ultrasound test that uses high-pitched
sound waves to produce an image of
the heart.
The sound waves are sent through a
device called a transducer and are
reflected off the various structures of
the heart. These echoes are converted
into pictures of the heart that can be
seen on a video monitor.
There is no special preparation for
the test.
8
Ultrasound gel is applied to the
transducer to allow transmission
of the sound waves from the
transducer to the skin
The transducer transforms the
echo (mechanical energy) into an
electrical signal which is processed
and displayed as an image on the
screen.
The conversion of sound to
electrical energy is called the
piezoelectric effect
9
Generation Of An Ultrasound Image
Principle of Image generation
Image Generation in M-Mode and 2D Echocardio graphy
Phased array
transduce r
P roce ssi ng and s can
conversion
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Piezoelectric
elements
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E c
h
o
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s
Ultrasound
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Heart
Time I
M- mode Im
age
2-D im ag e
Machine
8
There are 5 basic components of an ultrasound scanner that are required for
generation, display and storage of an ultrasound image.
1. Pulse generator - applies high amplitude voltage to energize the crystals
2. Transducer - converts electrical energy to mechanical (ultrasound) energy
and vice versa
3. Receiver - detects and amplifies weak signals
4. Display - displays ultrasound signals in a variety of modes
5. Memory - stores video display
THE TRANSDUCER
⚫ The transducer is responsible for both
transmitting and receiving the
ultrasound signal.
⚫ The transducer consist of a electrode and a
piezo-electric crystal whose ionic structure
results in deformation of shape when
exposed to an electric current.
⚫ Piezo electric(PE) crystals are composed of
synthetic material such as barium titanate
which when exposed to electric current
from the electrodes, alternately expand and
contract to create sound waves. When
subjected to the mechanical energy of
sound from a returning surface, the same
PE element change the shape thereby
generating an electrical signal detected by
the electrodes.
THE TRANSDUCER
Indications of 2D Echocardiography
1
• Indication for hemodynamic imaging
through doppler techniques:
• Blood flow through heart valves (stenosis/
regurgitation)
• Blood flow through the cardiac chambers
(C.O)
• Systolic and diastolic functions
V
18
⚫Transthoracic(standard echo)
Left parasternal
Apical
Subcostal
Suprasternal
⚫Transesophag
eal
ECHOCARDIOGRAPHY TYPE
ECHOCARDIOGRAPHY TYPE
ECHOCARDIOGRAPHY TYPE
ECHOCARDIOGRAPHY TYPE
Transthoracic Echo
A standard echocardiogram is also known
as a
transthoracic echocardiogram (TTE), or cardiac
ultrasound.
The subject is asked to lie in the semi recumbent
position on his or her left side with the head
elevated.
The left arm is tucked under the head and the
right arm
lies along the right side of the body
Standard positions on the chest wall are used for
placement of the transducer called “echo windows”
22
The Modalities of Echo
The following modalities of echo are used clinically:
1. Conventional echo
Two-Dimensional echo (2-D echo)
Motion- mode echo (M-mode echo)
2. Doppler Echo
Continuous wave (CW) Doppler
Pulse wave (PW) Doppler
Colour flow(CF) Doppler
All modalities follow the same principle of
ultrasound
Differ in how reflected sound waves are
collected 23
Two-Dimensional Echo (2-D echo)
This technique is used to "see" the actual
structures and motion of the heart
structures at work.
Ultrasound is transmitted along several
scan lines(90-120), over a wide arc(about
900) and many times per second.
The combination of reflected ultrasound
signals builds up an image on the display
screen.
A 2-D echo view appears cone shaped on
the monitor.
24
M-Mode echocardiography
An M- mode echocardiogram is not a
"picture" of the heart, but rather a
diagram that shows how the positions
of its structures change during the
course of the cardiac cycle.
M-mode recordings permit
measurement of cardiac dimensions
and motion patterns.
Also facilitate analysis of time
relationships with other physiological
variables such as ECG, and heart
sounds.
25
Modes of ECHO
⚫ A mode: basic mode - single scan line is passed through heart
⚫ B mode: repetative scan lines
⚫ M mode: movement of the heart can be obtained as a time- motion or M mode
recording providing dynamic cardiac images.
⚫ 2D echo: acquires multiple B mode scan lines that are alligned in the appropriate
anatomic location to form a wedge shaped sector image that provides additional
spatial information in either superoinferior or mediolateral directions.
Doppler echocardiography
49
Doppler echocardiography is a method for
detecting the direction and velocity of
moving blood within the heart.
Pulsed Wave (PW) useful for low velocity
flow e.g. MV flow
Continuous Wave (CW) useful for high
velocity flow e.g aortic stenosis
Color Flow (CF) Different colors are used
to designate the direction of blood flow.
red is flow toward, and blue is flow away
from the transducer with turbulent flow
shown as a mosaic pattern.
31
Standard positions on the chest wall are used for
placement of the transducer called “ echo windows”
32
33
Parasternal Long-Axis View
(PLAX)
Transducer position: left sternal edge;
2nd – 4th intercostal space
Marker dot direction: points towards
right shoulder
Most echo studies begin with this
view
It sets the stage for subsequent echo
views
Many structures seen from this view
34
PARASTERNAL LONG
AXIS VIEW
PLAX RIGHT VENTRICULAR INFLOW VIEW
PROBE – TILTED INFERIOR AND RIGHT
INDEX OF PROBE – TOWARD RIGHT HIP
STRUCTURE SEEN – RA, RV, TV
ONLY 2DE VIEW TO EXAMINE POSTERIOR
LEAFLET OF TV.
TR JET CAN BE VISUALISE AND MEASURE
PLAX RV OUTFLOW VIEW
IN PLAX VIEW – PROBE ANGULATED SUPERIOR
AND RIGHT
STRUCTURE SEEN – RVOT, PV, MPA & BIFURCATION
OF PA.
SUBVALVULAR & VALVULAR PS.
Parasternal Short Axis View (PSAX)
Transducer position: left sternal edge;
2nd – 4th intercostal space
Marker dot direction: points towards
left shoulder(900 clockwise from PLAX
view)
By tilting transducer on an axis
between the left hip and right
shoulder, short axis views are obtained
at different levels, from the aorta to
the LV apex.
Many structures seen
22
PSAX AT AORTIC VALVE LEVEL
90 DEGREE CLOCKWISE ROATION FROM PLAX VIEW
INDEX POINT ON PROBE – LEFT SHOULDER
STRUCTURE SEEN – AORTIC VALVE, RVOT, PV, MPA
RA,LA, TV
PV, MPA OR BIFURCATION – SUPERIOR & LEFT
TV – PROBE -> INFERIOR & RIGHT
LAA – PROBE -> INFERIOR & LEFT
PATHOLOGY SEEN – VSD (PERIMEMBRANOUS, SUBAORTIC &
SUBPULMONIC), ASD , PFO, PDA, RVOT & PV ABNORMALITY.
ABNORMALITIES OF CORONARY ARTERY CAN BE SEEN
PSAX at MV level
SLIDING PROBE INFERIOR AND LEFT TOWARDS APEX
STRUCTURE SEEN – LV (CIRCULAR), RV (CRESCENTIC)
MITRAL VALVE
PATHOLOGY SEEN :
MVP, MS & MR
RWMA OF 6 SEGMENT AT BASAL LEVEL
IVS ABNORMALITIES
PERICARDIAL ABNORMALITIES
VSD (MUSCULAR OR PERIMEMBRANOUS TYPE)
PSAX view at PM level
PROBE POSITION – SLIDING LITTLE INFERIOR AND LEFT
STRUCTURE SEEN : LV (CIRCULAR), RV (CRESCENTIC)
ALPM (4o’ clock), PMPM (8o’ clock)
PATHOLOGY SEEN :
RWMA OF 6 SEGMENT AT PM LEVEL
VSD (MUSCULAR)
PERICARDIAL EFFUSION
PSAX at the APEX
PROBE POSITION : SLIDING INFERIOR AND LEFT
STRUCTURE SEEN : LV APEX
RV NOT SEEN
PATHOLOGY SEEN :
RWMA IN 4 SEGMENT
VSD (MUSCULAR)
APICAL ABNORMALITY (NON-COMPACTION,
LV APICAL THROMBUS, LV APICAL ANEURYSM &
HCM (APICAL VARIANT))
PERICARDIAL PATHOLOGY
Apical 4-Chamber View (A4C VIEW)
LEFT LATERAL DECUBITUS POSITION
PROBE : PLACED AT APEX
INDEX POINT POSITION : LEFT SIDE (3-5o’
Clock position)
STRUCTURE SEEN :
APEX - TOP
LV – RIGHT SIDE
RV – LEFT SIDE
RA & LA – BOTTOM.
MV, TV & AV.
A4C VIEW
PATHOLOGY SEEN :
VALVULAR PATHOLGY – REGURGITANT &
STENOTIC PATHOLGY.
VSD
ASD
PERICARDIAL PATHOLGY
LV APICAL PATHOLOGY (THROMBUS, ANEURYSM)
IVS MOTION ABNORMALITY (CCP, TAMPONADE)
A4C VIEW MEASUREMENTS
LV VOLUME , AREA & EF.
CW SPECTRAL DOPPLER ACROSS MITRAL VALVE MEASURING - MV AREA BY PHT, PG.
A5C VIEW (APICAL 5 CHAMBER VIEW)
A5C VIEW BY – SLIGHT ANTERIOR ANGULATION
OF PROBE
STRICTURE SEEN :
LA,LV,RA,RV .
LVOT, AORTIC ROOT & AV.
MODIFIED A4C VIEW
PROBE TO POINT RIGHTWARD & MEDIALLY.
FOCUS ON RA & RV
MEASUREMENTS :
RV DIAMETER AT BASE AND MID LEVEL
RV SIZE
FAC OF RV (RV SYSTOLIC FUNCTION MAESURE)
TAPSE
RIMP
PEAK SYSTOLIC VELOCITY OF MEDIAL TV ANNULUS
VSD
ASD
PERICARDIAL PATHOLOGY
A2C VIEW (APICAL TWO CHAMBER VIEW)
POSITION : COUNTER CLOCKWISE ROTATION OF PROBE
BY 60 DEGREE FROM A4C VIEW.
STRUCTURE SEEN : ANTERIOR SEGMENT OF LV ON RIGHTSIDE
INFERIOR SEGMENT OF LEFT SIDE
LA
LAA ON RIGHT SIDE
PATHOLOGY SEEN :
RWMA OF ANTERIOR AND INFERIOR LV WALL
LAA PATHOLGY
RV & PAPILLARY MUSCLE NOT SEEN IN THIS VIEW
Apical 2-Chamber View (AP2CH)
APICAL LONG AXIS VIEW (A/K/A APICAL 3
CHAMBER VIEW)
POSITION:
FROM A4C – 120 DEGREE COUNTER CLOCKWISE ROATION
FROM A2C – 60 DEGREE COUNTER CLOCKWISE ROTATION
SIMILAR TO PLAX VIEW BUT LV APEX SEEN
STRCTURE SEEN :
LVOT, AV, PART OF RV & AORTIC ROOT – RIGHT
LV – LEFT SIDE
ANTEROSEPTAL ON RIGHT SIDE
INFEROLATERAL ON LEFT SIDE
LA & MV PATHOLOGY.
MR, AR AND AS.
SUBCOSTAL 4 CHAMBER VIEW (SC4C VIEW)
SUPINE, HIP & KNEE FLEXED & ABDOMINAL
WALL RELAXED, BEST IN INSPIRATION
PROBE POSITION : SUBXIPHOID REGION
INDEX POINT OF PROBE : LEFT SIDE
STRUCTURE SEEN :
RA & RV ON UPPER PART OF IMAGE
LA & LV ON LOWER PART OF IMAGE
IAS & IVS
MV & TV
SUBCOSTAL 4 CHAMBER VIEW (SC4C VIEW)
SUBCOSTAL 4 CHAMBER VIEW
PATHOLGY AND MEASUREMENTS:
RV FREE WALL THICKNESS
ASD, VSD
REGURGITANT LESION OF AV VALVES
PARICARDIAL PATHOLOGY (EFFUSION OR
THICKENING)
GOOD ACOUSTIC WINDOW IN
COPD PATIENT & POOR IN OBESE PT.
SUBCOSTAL SHORT AXIS VIEW
POSITION : 90 DEGREE COUNTER CLOCKWISE ROATION FROM
SC4C VIEW.
ANALOGOUS TO PSAX VIEW.
PROBE MOVE FROM MEDIAL TO LATERAL SIDE TO GET LONG AXIS
OF LV
SUBCOSTAL SHORT AXIS VIEW AT AV, MV, PM AND APEX LEVEL.
GOOD VIEW IN COPD PATIENT.
SUBCOSTAL VIEW OF IVC
POSITON : SUBXIPHOID REGION
INDEX POINT OF PROBE : SUPERIORLY
ULTRASOUND BEAM : POSTERIOR & RIGHT
IVC : THIN WALLED, COLLAPSIBLE WITH
INSPIRATION & NON-PULSATILE NATURE.
PATHOLOGY :
SYSTOLIC FLOW REVERSAL IN IVC IN SEVERE
TR
DISTENDED, NON-COLLAPSING IVC IN TS
THROMBUS IN IVC CAN BE SEEN
SUBCOSTAL VIEW OF THE ABDOMINAL AORTA
PROBE POSITION : LEFTWARD TO IVC PROBE POSITION.
PATHOLOGY OF ABDOMINAL AORTA :
ANEURYSM, DISEECTION OR PLAQUE.
DIASTOLIC FLOW REVERSAL IN SEVERE AR
CONTINUOUS FORWARD FLOW THROUGHOUT CARDIAC CYCLE S/O SEVERE COA.
•Transducer position: suprasternal notch
•Marker dot direction: points towards left shoulder
•The subject lies supine with the neck hyperexrended. The
head is rotated slightly towards the left
•The position of arms or legs and the phase of respiration
have no bearing on this echo window
4
SUPRASTERNAL LONG AXIS
VIEW OF THE AORTIC ARCH
SUPRASTERNAL LONG AXIS VIEW OF
THE AORTIC ARCH
STRUCTURE SEEN :
DESCENDING THORASIC AORTA
ARCH OF AORTA
ASCENDING AORTA
PATHOLOGY SEEN:
DISSECTION, ANEURYSM OR PLAQUE
DIASTOLIC FLOW REVERSAL IN AR
COA
TEE (TRANS ESOPHAGEAL ECHOCRDIOGRAPHY)
Used to assess posterior structures like LA or LAA Clinical success
of transesophageal echocardiography:-
⚫ First, the close proximity of the esophagus to the posterior wall of the heart makes
this approach ideal for examining several important structures.
⚫ Second, the ability to position the transducer in the esophagus or stomach for
extended periods provides an opportunity to monitor the heart over time, such as
during cardiac surgery.
⚫ Third, although more invasive than other forms of echocardiography, the
technique has proven to be extremely safe and well tolerated so that it can be
performed in critically ill patients and very small infants.
5
TEE (TRANS ESOPHAGEAL
ECHOCRDIOGRAPHY)
TEE VIEW
TEE VIEW
TEE INDICATION
Contraindications to
Transesophageal Echocardiography
71
Conclusion
72
Echocardiography provides a substantial amount
of structural and functional information about
the heart.
Still frames provide anatomical detail.
Dynamic images tell us about physiological
function
The quality of an echo is highly operator
dependent and proportional to experience and
skill, therefore the value of information derived
depends heavily upon who has performed it
CHAMBER QUANTIFICATION
LV SIZE AND FUNCTION
LV SIZE
Linear Measurements in PLAX (2D/M MODE)
LVID Diastole/ Systole (LVIDD/ LVIDS)
• Inner edge to inner edge, perpendicular to long
axis, at or immediately below the level of MV
leaflet tips
• LVIDD - End-diastole (the frame before MV
closure or with largest LV dimensions/volume)
• LVIDS - End-systole (AV closure or the smallest LV
dimension/volume)
• LVIDD – 42-58 MM/37-52 MM
• LVIDS- 25-39 MM/21-34 MM
M – MODE TRACING
2D-ECHO LINEAR measurement
Volume Measurement
2D
Biplane method of discs (modified Simpson’s
rule)
• A4C & A2C (LV focused) - End-diastole &
end-systole with clear endocardial border
definition (TRACING OF BLOOD TISSUE
INTERFACE)
• Papillary muscles excluded from tracing
• Maximize LV area and avoid LV APEX
foreshortening
• LVEDV (ML) – 106 (62-150)/76 (46-106)
• LVESV (ML) – 41 (21-61)/28 (14-42)
Volume Measurement
Area-length method
 Partial correction for shape distortion
 Apex frequently foreshortened
 Heavily based on geometrical assumptions
 Limited published data on normal population
Endocardial Border Enhancement
 When ≥ 2 contiguous endocardial
segments can’t be visualized in apical
views, contrast to be used.
 Avoid acoustic shadowing in the basal
segments of the LV when contrast
concentration is high
 Normal values for CE LV volumes not well
established, however - more reproducible
volumetric and EF data & correlation with
CMR
3D
• LV volumes from a “full volume” data set (raw data)
• LV focused volume (atria not important)
• Focus on including entire LV in the pyramidal dataset
and obtaining good endocardial border definition
• On most systems, the volume/frame rate >15Hz
• Semi-automated software
• No geometrical assumption needed
• Unaffected by foreshortening
• More accurate and reproducible (comparable to
CMR)
Normal values (LV size & function)
LV Mass
Linear Method (Cubed formula) – M MODE
 Prolate ellipsoid assumption of LV, with long axis to short axis ratio 2:1
 LVID, IVS, PW at end-Diastole,
LV mass = 0.8 x (1.04 x [ (IVS+LVID+PWT)3
- LVID3
] + 0.6 g
 Fast and widely used
 Wealth of published data
 Demonstrated prognostic value
 Fairly accurate in normally shaped ventricles
(i.e., systemic hypertension, aortic stenosis)
 Simple for screening large populations
 Over estimate LV mass
 Inaccurate in asymmetric hypertrophy, DCM or disease with regional
variation in wall thickness
2D-based formulas
Less depend on geometrical Assumption than linear
Cumbersome
Good image quality and epicardial definition needed
Limited prognostic value.
Minor axis
LV MASS (AREA-LENGTH METHOD)
Am = A1-A2
(mean wall thickness from epicardial &
Endocardial cross section area) in PSAX at PM level
LV MASS = LV VOLUME X MYOCARDIAL DENSITY (1.05 gm/mL)
LV MASS = (LV EPICARDIAL VOLUME – LV ENDOCARDIAL
VOLUME)X1.05 = LV MYOCARDIAL VOLUMEX1.05
Relative Wall Thickness (RWT)
 RWT = (2x posterior wall thickness)/(LVIDD)
 Categorize LV mass (concentric or eccentric) & pattern of
remodeling.
 RWT >0.42 = CONCENTRIC
 RWT <0.42 = ECCENTRIC
3D based LV MASS
measurement
• Direct measurement without
geometrical assumptions of LV cavity
shape & hypertrophy distribution.
• More accurate than linear or 2D
• Higher reproducibility
• Better discriminates small changes
within a patient
• Normal values less well established
LV MASS INDICES
NORMAL SHAPED LV = M-MODE OR 2D-ECHO
ABNORMAL SHAPED LV = 3D-ECHO
Normal values (LV mass indices)
CORRECT LINEAR MEASUREMENTS (PITFALLS TO AVOID)
Don’t measure too proximal (near
aortic root)
Don’t include RV
trabeculations
Avoid papillary muscles inclusion in PW
Avoid measuring IVS at sigmoid
septum
Left Ventricular Function Assessment
LV Global Systolic Function Parameters
 Fractional Shortening (discouraged)
o FS% = LVIDD – LVIDS / LVIDD x 100 (normal > 25%)
o M-mode or 2D
Linear measure problematic – When RMWA or conduction
abnormality or chamber dilation present.
 EF derived from LVEDV and LVESV (biplane method)
LVEF% = LVEDV – LVESV / LVEDV x 100
(3D ECHO based EF – ACCURATE AND REPRODUCIBLE)
 Global Longitudinal Strain
Global Longitudinal Strain (GLS) by STE
• Peak GLS (%) = (MLs-MLd)/MLd
(MLs= myocardial length end-systole, MLd= myocardial length
end-diastole)
MLs is smaller than MLd, so peak GLS is negative number.
• CW of AV, or PW of LVOT for timing of AV opening &
closure
• 3 standard apical views at a frame rate of 60Hz-90Hz
Heart rate should not vary more than 5bpm
• As a general guide, a peak GLS of -20% can be considered
normal
• GLS calculation should be avoided, if suboptimal result of
tracing in > 2 segments  MAPSE or DTI derived mitral
annular peak systolic velocity S’.
Normal LV strain values - meta-analysis
and individual recent publications
Takigiku K, Takeuchi M, Izumi C, Yuda S, Sakata K, Ohte N, et al. Normal range of left
ventricular 2-dimensional strain: Japanese Ultrasound Speckle Tracking of the Left
Ventricle (JUSTICE) study. Circ J 2012;76:2623-32.
LV Regional Function
SEGMENTAL
ORIENTATION IN
DIFFERENT
VIEWS
CORONARY ARTERY TERRITORIES
17-SEGMENT MODEL
• Apex divided into 5 segments - septal, inferior, lateral,
anterior, and ‘‘apical cap’’ (myocardium beyond the end of
LV cavity)
• May be used for perfusion studies or comparison b/w
different imaging modalities, specifically SPECT, PET, and
CMR
• Apical cap not included (16 segment model) for wall
motion or regional strain
RV SIZE AND FUNCTION
Essential views for imaging and assessment:
 Left PLAX
 Left PSAX
 Left parasternal RV inflow view
 Apical 4-chamber view
 Focused apical 4-chamber RV view
 Modified apical 4-chamber view
 Subcostal views
RV Size
• Should be routinely assessed using
multiple windows
• All chamber measurements inner-edge to
inner-edge
• Report both qualitative and quantitative
parameters
• Most of the values not indexed to gender,
BSA, or height
• RV diameter - RV focused A4C (LV apex
in center & largest basal RV diameter),
end diastole
• As dimensions depend on probe
rotation & the view, always state the
window
• RV diameter of >41mm at base &
>35mm at mid-level is abnormal
RV wall thickness
 2D or M-mode at end-diastole, zoomed, RV mid- wall
(preferably subcostal view)
 below the TV annulus at a distance approx. the length of
ant tricuspid leaflet, when it is fully open & parallel RV free
wall
 >5mm is abnormal
 Trabeculae, papillary ms and
 Epicardial fat should be excluded.
 Challenging – when thickened visceral
pericardium
RV Function
RV systolic function should be assessed by at least one or a
combination of the following parameters:
1. TAPSE (Tricuspid Annular Plane Systolic Excursion)
2. DTI-Derived Tricuspid Lateral Annular Systolic Velocity S’
3. FAC (fractional area change)
4. RV longitudinal strain
5. 3D EF
6. Right Index of Myocardial Performance (RIMP or MPI)
RIMP (Right Index of Myocardial
performance) (Tei index)
 assesses global RV function
 requires beats with similar RR intervals
 unreliable when RA pressure is elevated
 IVCT, IVRT and ET from PW of TV inflow & RVOT,
or DTI of lateral TV annulus (values differ by method)
RIMP = (TCO – ET)/ET,
where TCO is the TV closure to opening time
RIMP >0.43 by PW Doppler & >0.54 by DTI s/o
RV DYSFUNCTION.
DTI – single beat recording, no need for R-R interval
matching, which is needed in PW
PW SPECTRAL DOPPLER
DTI OF LATERAL TRICUSPID ANNULUS
FAC
 reflects both longitudinal & radial components of RV
contraction
 correlates with RV EF by CMR
 does not include the contribution of RV outflow tract to
systolic function
• RV FAC % = EDA-ESA/EDAX100
• GLOBAL RV SYSTOLIC FUNCTION
<35% FAC s/o RV SYSTOLIC
DYSFUNCTION
RV FOCUSED APICAL 4 CHAMBER VIEW
RV 3D EF
 includes RVOT contribution to overall function
 post cardiac surgery pts – conventional indices
(TAPSE, S wave) no longer representative of RV
function
 slightly higher in women, because of smaller
volumes
 <45% s/o RV SYSTOLIC DYSFUNCTION
 Limitation - load dependency,
interventricular changes affecting
septal motion,
poor acoustic windows,
& irregular rhythms
TAPSE
 predominantly RV longitudinal function; good correlation
with parameters estimating RV global systolic function
 may over- or underestimate RV function due to cardiac
translation
 angle dependency
 established prognostic value
 Measure by M-MODE.
 TAPSE <17 mm s/o RV
SYSTOLIC DYSFUNCTION.
DTI -derived tricuspid lateral annular systolic
velocity S’
 Longitudinal RV function, established prognostic value
 may be inaccurate in post thoracotomy, pulmonary
thromboendarterectomy or heart transplantation
 angle dependent
 <9.5 cm/sec on free wall
s/o RVSD
Peak systolic velocity of tricuspid
Annulus by PW-DTI
Easy, reproducible, prognostic value.
RV longitudinal strain
 Less confounded by overall heart
motion, but depends on RV loading
conditions as well as RV size and shape
 RV-focused view
 Normal value is approximately -20%
 AVERAGED over 3 segment of RV free
wall.
RV FOCUSED A4C
Normal values for parameters of RV function
LA AREA/ VOLUME MEASUREMENTS
• End-systole when the LA chamber is at its greatest (prior to MV
opening)
• Avoid foreshortening
• Dedicated acquisition (apical) - maximize LA length & align true long
axis of LA
• For tracing area/volume, exclude confluences of PVs & LA
appendage
• AV interface represented by the mitral annulus plane
LA Anterior-Posterior (AP)
dimension
• Should not be used as sole LA
measurement (does not represent
accurate LA size)
• 2D measure preferred over M-mode
• Perpendicular to long axis of LA
posterior wall, Leading-leading
(M-mode) or Inner-Inner (2DE)
• Measured at the level of aortic sinuses
LA Area
• A4C & A2C
• Base of LA should be at its largest
• Trace LA inner border, excluding area under
MV annulus, PVs and LA appendage
LA Volume (Preferred over linear
or area-length method)
 Trace LA inner border, excl. area under
MV annulus, PVs, and LA appendage from
A4C & A2C views
 Area-length technique: Length (L)
measured from the shorter of the two
long axes in 4C/2C views
 Biplane summation of discs (preferred)
CORRECT METHOD OF LINEAR
MEASUREMENTS
NORMAL VALUES – LA
DIMENSIONS
RA AREA & VOLUME MEASUREMENTS
RA area
• End-systole, at its greatest dimension, prior
to TV opening
• Dedicated right heart view (an A4C view
that includes entire RA and is not
foreshortened)
• RA length should be maximized by
alignment along the true long axis of RA
• Base of the RA should be at its largest size
• Planimetry - exclude area under TV annulus
& confluences of RA appendage
RA Volume (single plane)
• More robust and accurate
• A4C dedicated right heart view
• No standard orthogonal RA view - so a
single-view area-length and/or disk
summation technique should be used
• Area-length method: Length performed
at center of area under the TV annulus
to the superior RA wall.
NORMAL VALUES -
RA SIZE
Aortic Root
• Maximal diameter at the sinuses of Valsalva
(PLAX)
• Moving closer to sternum and/or a higher ICS
allows better visual of ascending aorta
• Measure in view that depicts maximum diameter,
perpendicular to long axis aorta, and at end-
diastole
• Leading edge to leading edge for root & aorta
• 2D measurements preferable to M-mode,
(cardiac motion may result in changes in position
of M-mode cursor
AORTA
Aortic annulus
• Not a true or distinct anatomic structure (“virtual
ring” defined by joining basal
attachments of 3 aortic leaflets)
• uppermost attachments of leaflets, in the shape of
a crown, forms a true anatomic ring
• Zoom mode, mid-systole, when annulus slightly
larger and rounder (than diastole)
• B/w hinge points of leaflets (usually hinge point of
RCC & commissure b/w LCC/NCC) - inner edge to
inner edge
• Calcium protuberances are part of lumen, and
excluded from diameter
LVOT
• ASE recommends atleast 3 measurements of LVOT
• Zoom mode, mid-systole, Inner to Inner edge,
perpendicular to long axis of LVOT
• The largest measurement is used for the
continuity equation
• In the absence of pre-valvular acceleration, the
ASE states that it is acceptable to measure LVOT
at the level of annulus
• In AS, cursor is backed away from AV during LVOT
velocity measurement (A5C), & LVOT
measurement (PLAX) should be backed by the
same distance from AV
AORTIC ROOT DIMENSIONS IN NORMAL ADULTS
INFERIOR VENA CAVA
2D Echo
• Subcostal long axis view, with the patient
supine
• Open up IVC, so that diameter at fullest
along the entire length
• Inner-to-Inner Edge (I-I)
• Measure perpendicular to the vessel, 1-2
cm from IVC-RA junction
• DON’T measure at the junction of IVC &
RA
M-Mode (Assessing the collapsibility/sniff
test)
• Excellent for degree of inspiratory collapse
• Better interrogation over time (pre sniff, sniff and post
sniff) in the same image
• Often requires a brief sniff, as normal inspiration may not
elicit this response
• Based on IVC size (< or >2.1 cm) & collapsibility index (< or >50%):
• When not to use IVC for RAP estimation?
o Healthy young athletes may have dilated IVC in
presence of normal pressures
o IVC is commonly dilated and may not collapse in
patients on ventilators
RIGHT ATRIAL PRESSURE
(RAP)
THANK
YOU

Basics of transoesphageal echocardiography

  • 1.
    Dr Manasi Baranwal FortisEscorts Heart Institute ECHO: BASIC VIEW AND FINDING IN NORMAL TTE & TEE
  • 2.
    2 Echo is somethingyou experience all the time. If you shout into a well, the echo comes back a moment later. The echo occurs because some of the sound waves in your shout reflect off a surface (either the water at the bottom of the well or the wall on the far side) and travel back to your ears. A similar principle applies in cardiac ultrasound. ECHO
  • 3.
    HISTORY Christian Andreas Doppler- Austrian mathematician and physicist. (1803- 1853) He is celebrated for his principle – known as the Doppler effect (1842) – that the observed frequency of a wave depends on the relative speed of the source and the observer. He used this concept to explain the colour of binary stars
  • 4.
    PIEZOELECTRIC EFFECT The abilityto create ultrasonic waves came in 1880 with the discovery of PEIZOELECTRICITY by Curie and Curie. Jacques Curie (1855 – 1941) was a French physicist ,Along with his younger brother, Pierre curie The brothers Curie thought there would be a direct correlation between the potential generated by temperature changes and the mechanical strain that gave rise to piezoelectricity
  • 5.
  • 6.
    HISTORY Carl Hellmuth Hertz- German physicist known for involved in the development of inkjet technology and ultrasound technology. Carl Hellmuth Hertz Inge Gudmar Edler (1911 – 2001) Swedish cardiologist, who in collaboration with Carl Hellmuth Hertz developed medical ultrasonography and echocardiography. Edler and Hertz shared the 1977 Lasker-DeBakey Clinical Medical Research Award for this achievement Inge Gudmar Edler
  • 7.
    Dr. Helmut Hertzof Sweden in 1953 obtained a commercial ultrasonoscope, which was being used for nondestructive testing. He then collaborated with Dr. Inge Edler who was a practicing cardiologist in Sweden. The two of them began to use this commercial ultrasonoscope to examine the heart. This collaboration is commonly accepted as the beginning of clinical echocardiography as we know it today. Edler finally established the characteristic motion pattern for the anterior leaflet of the mitral valve. He compared the shape of the fast moving echoes in patients with enlarged hearts due to mitral stenosis during cardiac operations, and found empirically the shape correlated well with the severity of the stenosis. By early 1955, Edler had so much evidence of this relationship that he relied on ultrasound alone for the diagnosis of mitral stenosis. HISTORY
  • 8.
    Generation Of AnUltrasound Image Echocardiography (echo or echocardiogram) is a type of ultrasound test that uses high-pitched sound waves to produce an image of the heart. The sound waves are sent through a device called a transducer and are reflected off the various structures of the heart. These echoes are converted into pictures of the heart that can be seen on a video monitor. There is no special preparation for the test. 8
  • 9.
    Ultrasound gel isapplied to the transducer to allow transmission of the sound waves from the transducer to the skin The transducer transforms the echo (mechanical energy) into an electrical signal which is processed and displayed as an image on the screen. The conversion of sound to electrical energy is called the piezoelectric effect 9 Generation Of An Ultrasound Image
  • 11.
    Principle of Imagegeneration Image Generation in M-Mode and 2D Echocardio graphy Phased array transduce r P roce ssi ng and s can conversion l Piezoelectric elements _,- } "­ E c h o e s Ultrasound l pulses Heart Time I M- mode Im age 2-D im ag e
  • 13.
    Machine 8 There are 5basic components of an ultrasound scanner that are required for generation, display and storage of an ultrasound image. 1. Pulse generator - applies high amplitude voltage to energize the crystals 2. Transducer - converts electrical energy to mechanical (ultrasound) energy and vice versa 3. Receiver - detects and amplifies weak signals 4. Display - displays ultrasound signals in a variety of modes 5. Memory - stores video display
  • 14.
    THE TRANSDUCER ⚫ Thetransducer is responsible for both transmitting and receiving the ultrasound signal. ⚫ The transducer consist of a electrode and a piezo-electric crystal whose ionic structure results in deformation of shape when exposed to an electric current. ⚫ Piezo electric(PE) crystals are composed of synthetic material such as barium titanate which when exposed to electric current from the electrodes, alternately expand and contract to create sound waves. When subjected to the mechanical energy of sound from a returning surface, the same PE element change the shape thereby generating an electrical signal detected by the electrodes.
  • 15.
  • 17.
    Indications of 2DEchocardiography 1 • Indication for hemodynamic imaging through doppler techniques: • Blood flow through heart valves (stenosis/ regurgitation) • Blood flow through the cardiac chambers (C.O) • Systolic and diastolic functions V
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
    Transthoracic Echo A standardechocardiogram is also known as a transthoracic echocardiogram (TTE), or cardiac ultrasound. The subject is asked to lie in the semi recumbent position on his or her left side with the head elevated. The left arm is tucked under the head and the right arm lies along the right side of the body Standard positions on the chest wall are used for placement of the transducer called “echo windows” 22
  • 23.
    The Modalities ofEcho The following modalities of echo are used clinically: 1. Conventional echo Two-Dimensional echo (2-D echo) Motion- mode echo (M-mode echo) 2. Doppler Echo Continuous wave (CW) Doppler Pulse wave (PW) Doppler Colour flow(CF) Doppler All modalities follow the same principle of ultrasound Differ in how reflected sound waves are collected 23
  • 24.
    Two-Dimensional Echo (2-Decho) This technique is used to "see" the actual structures and motion of the heart structures at work. Ultrasound is transmitted along several scan lines(90-120), over a wide arc(about 900) and many times per second. The combination of reflected ultrasound signals builds up an image on the display screen. A 2-D echo view appears cone shaped on the monitor. 24
  • 25.
    M-Mode echocardiography An M-mode echocardiogram is not a "picture" of the heart, but rather a diagram that shows how the positions of its structures change during the course of the cardiac cycle. M-mode recordings permit measurement of cardiac dimensions and motion patterns. Also facilitate analysis of time relationships with other physiological variables such as ECG, and heart sounds. 25
  • 26.
    Modes of ECHO ⚫A mode: basic mode - single scan line is passed through heart ⚫ B mode: repetative scan lines ⚫ M mode: movement of the heart can be obtained as a time- motion or M mode recording providing dynamic cardiac images. ⚫ 2D echo: acquires multiple B mode scan lines that are alligned in the appropriate anatomic location to form a wedge shaped sector image that provides additional spatial information in either superoinferior or mediolateral directions.
  • 28.
    Doppler echocardiography 49 Doppler echocardiographyis a method for detecting the direction and velocity of moving blood within the heart. Pulsed Wave (PW) useful for low velocity flow e.g. MV flow Continuous Wave (CW) useful for high velocity flow e.g aortic stenosis Color Flow (CF) Different colors are used to designate the direction of blood flow. red is flow toward, and blue is flow away from the transducer with turbulent flow shown as a mosaic pattern.
  • 31.
  • 32.
    Standard positions onthe chest wall are used for placement of the transducer called “ echo windows” 32
  • 33.
  • 34.
    Parasternal Long-Axis View (PLAX) Transducerposition: left sternal edge; 2nd – 4th intercostal space Marker dot direction: points towards right shoulder Most echo studies begin with this view It sets the stage for subsequent echo views Many structures seen from this view 34
  • 36.
  • 38.
    PLAX RIGHT VENTRICULARINFLOW VIEW PROBE – TILTED INFERIOR AND RIGHT INDEX OF PROBE – TOWARD RIGHT HIP STRUCTURE SEEN – RA, RV, TV ONLY 2DE VIEW TO EXAMINE POSTERIOR LEAFLET OF TV. TR JET CAN BE VISUALISE AND MEASURE
  • 39.
    PLAX RV OUTFLOWVIEW IN PLAX VIEW – PROBE ANGULATED SUPERIOR AND RIGHT STRUCTURE SEEN – RVOT, PV, MPA & BIFURCATION OF PA. SUBVALVULAR & VALVULAR PS.
  • 40.
    Parasternal Short AxisView (PSAX) Transducer position: left sternal edge; 2nd – 4th intercostal space Marker dot direction: points towards left shoulder(900 clockwise from PLAX view) By tilting transducer on an axis between the left hip and right shoulder, short axis views are obtained at different levels, from the aorta to the LV apex. Many structures seen 22
  • 44.
    PSAX AT AORTICVALVE LEVEL 90 DEGREE CLOCKWISE ROATION FROM PLAX VIEW INDEX POINT ON PROBE – LEFT SHOULDER STRUCTURE SEEN – AORTIC VALVE, RVOT, PV, MPA RA,LA, TV PV, MPA OR BIFURCATION – SUPERIOR & LEFT TV – PROBE -> INFERIOR & RIGHT LAA – PROBE -> INFERIOR & LEFT PATHOLOGY SEEN – VSD (PERIMEMBRANOUS, SUBAORTIC & SUBPULMONIC), ASD , PFO, PDA, RVOT & PV ABNORMALITY. ABNORMALITIES OF CORONARY ARTERY CAN BE SEEN
  • 45.
    PSAX at MVlevel SLIDING PROBE INFERIOR AND LEFT TOWARDS APEX STRUCTURE SEEN – LV (CIRCULAR), RV (CRESCENTIC) MITRAL VALVE PATHOLOGY SEEN : MVP, MS & MR RWMA OF 6 SEGMENT AT BASAL LEVEL IVS ABNORMALITIES PERICARDIAL ABNORMALITIES VSD (MUSCULAR OR PERIMEMBRANOUS TYPE)
  • 46.
    PSAX view atPM level PROBE POSITION – SLIDING LITTLE INFERIOR AND LEFT STRUCTURE SEEN : LV (CIRCULAR), RV (CRESCENTIC) ALPM (4o’ clock), PMPM (8o’ clock) PATHOLOGY SEEN : RWMA OF 6 SEGMENT AT PM LEVEL VSD (MUSCULAR) PERICARDIAL EFFUSION
  • 47.
    PSAX at theAPEX PROBE POSITION : SLIDING INFERIOR AND LEFT STRUCTURE SEEN : LV APEX RV NOT SEEN PATHOLOGY SEEN : RWMA IN 4 SEGMENT VSD (MUSCULAR) APICAL ABNORMALITY (NON-COMPACTION, LV APICAL THROMBUS, LV APICAL ANEURYSM & HCM (APICAL VARIANT)) PERICARDIAL PATHOLOGY
  • 49.
    Apical 4-Chamber View(A4C VIEW) LEFT LATERAL DECUBITUS POSITION PROBE : PLACED AT APEX INDEX POINT POSITION : LEFT SIDE (3-5o’ Clock position) STRUCTURE SEEN : APEX - TOP LV – RIGHT SIDE RV – LEFT SIDE RA & LA – BOTTOM. MV, TV & AV.
  • 50.
    A4C VIEW PATHOLOGY SEEN: VALVULAR PATHOLGY – REGURGITANT & STENOTIC PATHOLGY. VSD ASD PERICARDIAL PATHOLGY LV APICAL PATHOLOGY (THROMBUS, ANEURYSM) IVS MOTION ABNORMALITY (CCP, TAMPONADE)
  • 51.
    A4C VIEW MEASUREMENTS LVVOLUME , AREA & EF.
  • 52.
    CW SPECTRAL DOPPLERACROSS MITRAL VALVE MEASURING - MV AREA BY PHT, PG.
  • 53.
    A5C VIEW (APICAL5 CHAMBER VIEW) A5C VIEW BY – SLIGHT ANTERIOR ANGULATION OF PROBE STRICTURE SEEN : LA,LV,RA,RV . LVOT, AORTIC ROOT & AV.
  • 54.
    MODIFIED A4C VIEW PROBETO POINT RIGHTWARD & MEDIALLY. FOCUS ON RA & RV MEASUREMENTS : RV DIAMETER AT BASE AND MID LEVEL RV SIZE FAC OF RV (RV SYSTOLIC FUNCTION MAESURE) TAPSE RIMP PEAK SYSTOLIC VELOCITY OF MEDIAL TV ANNULUS VSD ASD PERICARDIAL PATHOLOGY
  • 55.
    A2C VIEW (APICALTWO CHAMBER VIEW) POSITION : COUNTER CLOCKWISE ROTATION OF PROBE BY 60 DEGREE FROM A4C VIEW. STRUCTURE SEEN : ANTERIOR SEGMENT OF LV ON RIGHTSIDE INFERIOR SEGMENT OF LEFT SIDE LA LAA ON RIGHT SIDE PATHOLOGY SEEN : RWMA OF ANTERIOR AND INFERIOR LV WALL LAA PATHOLGY RV & PAPILLARY MUSCLE NOT SEEN IN THIS VIEW
  • 56.
  • 57.
    APICAL LONG AXISVIEW (A/K/A APICAL 3 CHAMBER VIEW) POSITION: FROM A4C – 120 DEGREE COUNTER CLOCKWISE ROATION FROM A2C – 60 DEGREE COUNTER CLOCKWISE ROTATION SIMILAR TO PLAX VIEW BUT LV APEX SEEN STRCTURE SEEN : LVOT, AV, PART OF RV & AORTIC ROOT – RIGHT LV – LEFT SIDE ANTEROSEPTAL ON RIGHT SIDE INFEROLATERAL ON LEFT SIDE LA & MV PATHOLOGY. MR, AR AND AS.
  • 58.
    SUBCOSTAL 4 CHAMBERVIEW (SC4C VIEW)
  • 59.
    SUPINE, HIP &KNEE FLEXED & ABDOMINAL WALL RELAXED, BEST IN INSPIRATION PROBE POSITION : SUBXIPHOID REGION INDEX POINT OF PROBE : LEFT SIDE STRUCTURE SEEN : RA & RV ON UPPER PART OF IMAGE LA & LV ON LOWER PART OF IMAGE IAS & IVS MV & TV SUBCOSTAL 4 CHAMBER VIEW (SC4C VIEW)
  • 60.
    SUBCOSTAL 4 CHAMBERVIEW PATHOLGY AND MEASUREMENTS: RV FREE WALL THICKNESS ASD, VSD REGURGITANT LESION OF AV VALVES PARICARDIAL PATHOLOGY (EFFUSION OR THICKENING) GOOD ACOUSTIC WINDOW IN COPD PATIENT & POOR IN OBESE PT.
  • 61.
    SUBCOSTAL SHORT AXISVIEW POSITION : 90 DEGREE COUNTER CLOCKWISE ROATION FROM SC4C VIEW. ANALOGOUS TO PSAX VIEW. PROBE MOVE FROM MEDIAL TO LATERAL SIDE TO GET LONG AXIS OF LV SUBCOSTAL SHORT AXIS VIEW AT AV, MV, PM AND APEX LEVEL. GOOD VIEW IN COPD PATIENT.
  • 62.
    SUBCOSTAL VIEW OFIVC POSITON : SUBXIPHOID REGION INDEX POINT OF PROBE : SUPERIORLY ULTRASOUND BEAM : POSTERIOR & RIGHT IVC : THIN WALLED, COLLAPSIBLE WITH INSPIRATION & NON-PULSATILE NATURE. PATHOLOGY : SYSTOLIC FLOW REVERSAL IN IVC IN SEVERE TR DISTENDED, NON-COLLAPSING IVC IN TS THROMBUS IN IVC CAN BE SEEN
  • 63.
    SUBCOSTAL VIEW OFTHE ABDOMINAL AORTA PROBE POSITION : LEFTWARD TO IVC PROBE POSITION. PATHOLOGY OF ABDOMINAL AORTA : ANEURYSM, DISEECTION OR PLAQUE. DIASTOLIC FLOW REVERSAL IN SEVERE AR CONTINUOUS FORWARD FLOW THROUGHOUT CARDIAC CYCLE S/O SEVERE COA.
  • 64.
    •Transducer position: suprasternalnotch •Marker dot direction: points towards left shoulder •The subject lies supine with the neck hyperexrended. The head is rotated slightly towards the left •The position of arms or legs and the phase of respiration have no bearing on this echo window 4 SUPRASTERNAL LONG AXIS VIEW OF THE AORTIC ARCH
  • 65.
    SUPRASTERNAL LONG AXISVIEW OF THE AORTIC ARCH STRUCTURE SEEN : DESCENDING THORASIC AORTA ARCH OF AORTA ASCENDING AORTA PATHOLOGY SEEN: DISSECTION, ANEURYSM OR PLAQUE DIASTOLIC FLOW REVERSAL IN AR COA
  • 66.
    TEE (TRANS ESOPHAGEALECHOCRDIOGRAPHY)
  • 67.
    Used to assessposterior structures like LA or LAA Clinical success of transesophageal echocardiography:- ⚫ First, the close proximity of the esophagus to the posterior wall of the heart makes this approach ideal for examining several important structures. ⚫ Second, the ability to position the transducer in the esophagus or stomach for extended periods provides an opportunity to monitor the heart over time, such as during cardiac surgery. ⚫ Third, although more invasive than other forms of echocardiography, the technique has proven to be extremely safe and well tolerated so that it can be performed in critically ill patients and very small infants. 5 TEE (TRANS ESOPHAGEAL ECHOCRDIOGRAPHY)
  • 68.
  • 69.
  • 70.
  • 71.
  • 72.
    Conclusion 72 Echocardiography provides asubstantial amount of structural and functional information about the heart. Still frames provide anatomical detail. Dynamic images tell us about physiological function The quality of an echo is highly operator dependent and proportional to experience and skill, therefore the value of information derived depends heavily upon who has performed it
  • 74.
  • 75.
    LV SIZE ANDFUNCTION LV SIZE Linear Measurements in PLAX (2D/M MODE) LVID Diastole/ Systole (LVIDD/ LVIDS) • Inner edge to inner edge, perpendicular to long axis, at or immediately below the level of MV leaflet tips • LVIDD - End-diastole (the frame before MV closure or with largest LV dimensions/volume) • LVIDS - End-systole (AV closure or the smallest LV dimension/volume) • LVIDD – 42-58 MM/37-52 MM • LVIDS- 25-39 MM/21-34 MM M – MODE TRACING 2D-ECHO LINEAR measurement
  • 76.
    Volume Measurement 2D Biplane methodof discs (modified Simpson’s rule) • A4C & A2C (LV focused) - End-diastole & end-systole with clear endocardial border definition (TRACING OF BLOOD TISSUE INTERFACE) • Papillary muscles excluded from tracing • Maximize LV area and avoid LV APEX foreshortening • LVEDV (ML) – 106 (62-150)/76 (46-106) • LVESV (ML) – 41 (21-61)/28 (14-42)
  • 77.
  • 78.
    Area-length method  Partialcorrection for shape distortion  Apex frequently foreshortened  Heavily based on geometrical assumptions  Limited published data on normal population
  • 79.
    Endocardial Border Enhancement When ≥ 2 contiguous endocardial segments can’t be visualized in apical views, contrast to be used.  Avoid acoustic shadowing in the basal segments of the LV when contrast concentration is high  Normal values for CE LV volumes not well established, however - more reproducible volumetric and EF data & correlation with CMR
  • 80.
    3D • LV volumesfrom a “full volume” data set (raw data) • LV focused volume (atria not important) • Focus on including entire LV in the pyramidal dataset and obtaining good endocardial border definition • On most systems, the volume/frame rate >15Hz • Semi-automated software • No geometrical assumption needed • Unaffected by foreshortening • More accurate and reproducible (comparable to CMR)
  • 81.
    Normal values (LVsize & function)
  • 82.
    LV Mass Linear Method(Cubed formula) – M MODE  Prolate ellipsoid assumption of LV, with long axis to short axis ratio 2:1  LVID, IVS, PW at end-Diastole, LV mass = 0.8 x (1.04 x [ (IVS+LVID+PWT)3 - LVID3 ] + 0.6 g  Fast and widely used  Wealth of published data  Demonstrated prognostic value  Fairly accurate in normally shaped ventricles (i.e., systemic hypertension, aortic stenosis)  Simple for screening large populations  Over estimate LV mass  Inaccurate in asymmetric hypertrophy, DCM or disease with regional variation in wall thickness
  • 83.
    2D-based formulas Less dependon geometrical Assumption than linear Cumbersome Good image quality and epicardial definition needed Limited prognostic value. Minor axis
  • 84.
    LV MASS (AREA-LENGTHMETHOD) Am = A1-A2 (mean wall thickness from epicardial & Endocardial cross section area) in PSAX at PM level LV MASS = LV VOLUME X MYOCARDIAL DENSITY (1.05 gm/mL) LV MASS = (LV EPICARDIAL VOLUME – LV ENDOCARDIAL VOLUME)X1.05 = LV MYOCARDIAL VOLUMEX1.05
  • 85.
    Relative Wall Thickness(RWT)  RWT = (2x posterior wall thickness)/(LVIDD)  Categorize LV mass (concentric or eccentric) & pattern of remodeling.  RWT >0.42 = CONCENTRIC  RWT <0.42 = ECCENTRIC
  • 86.
    3D based LVMASS measurement • Direct measurement without geometrical assumptions of LV cavity shape & hypertrophy distribution. • More accurate than linear or 2D • Higher reproducibility • Better discriminates small changes within a patient • Normal values less well established
  • 87.
    LV MASS INDICES NORMALSHAPED LV = M-MODE OR 2D-ECHO ABNORMAL SHAPED LV = 3D-ECHO
  • 88.
    Normal values (LVmass indices)
  • 89.
    CORRECT LINEAR MEASUREMENTS(PITFALLS TO AVOID) Don’t measure too proximal (near aortic root) Don’t include RV trabeculations
  • 90.
    Avoid papillary musclesinclusion in PW Avoid measuring IVS at sigmoid septum
  • 91.
    Left Ventricular FunctionAssessment LV Global Systolic Function Parameters  Fractional Shortening (discouraged) o FS% = LVIDD – LVIDS / LVIDD x 100 (normal > 25%) o M-mode or 2D Linear measure problematic – When RMWA or conduction abnormality or chamber dilation present.  EF derived from LVEDV and LVESV (biplane method) LVEF% = LVEDV – LVESV / LVEDV x 100 (3D ECHO based EF – ACCURATE AND REPRODUCIBLE)  Global Longitudinal Strain
  • 92.
    Global Longitudinal Strain(GLS) by STE • Peak GLS (%) = (MLs-MLd)/MLd (MLs= myocardial length end-systole, MLd= myocardial length end-diastole) MLs is smaller than MLd, so peak GLS is negative number. • CW of AV, or PW of LVOT for timing of AV opening & closure • 3 standard apical views at a frame rate of 60Hz-90Hz Heart rate should not vary more than 5bpm • As a general guide, a peak GLS of -20% can be considered normal • GLS calculation should be avoided, if suboptimal result of tracing in > 2 segments  MAPSE or DTI derived mitral annular peak systolic velocity S’.
  • 93.
    Normal LV strainvalues - meta-analysis and individual recent publications Takigiku K, Takeuchi M, Izumi C, Yuda S, Sakata K, Ohte N, et al. Normal range of left ventricular 2-dimensional strain: Japanese Ultrasound Speckle Tracking of the Left Ventricle (JUSTICE) study. Circ J 2012;76:2623-32.
  • 94.
  • 95.
  • 96.
  • 97.
    17-SEGMENT MODEL • Apexdivided into 5 segments - septal, inferior, lateral, anterior, and ‘‘apical cap’’ (myocardium beyond the end of LV cavity) • May be used for perfusion studies or comparison b/w different imaging modalities, specifically SPECT, PET, and CMR • Apical cap not included (16 segment model) for wall motion or regional strain
  • 98.
    RV SIZE ANDFUNCTION Essential views for imaging and assessment:  Left PLAX  Left PSAX  Left parasternal RV inflow view  Apical 4-chamber view  Focused apical 4-chamber RV view  Modified apical 4-chamber view  Subcostal views
  • 99.
    RV Size • Shouldbe routinely assessed using multiple windows • All chamber measurements inner-edge to inner-edge • Report both qualitative and quantitative parameters • Most of the values not indexed to gender, BSA, or height
  • 100.
    • RV diameter- RV focused A4C (LV apex in center & largest basal RV diameter), end diastole • As dimensions depend on probe rotation & the view, always state the window • RV diameter of >41mm at base & >35mm at mid-level is abnormal
  • 102.
    RV wall thickness 2D or M-mode at end-diastole, zoomed, RV mid- wall (preferably subcostal view)  below the TV annulus at a distance approx. the length of ant tricuspid leaflet, when it is fully open & parallel RV free wall  >5mm is abnormal  Trabeculae, papillary ms and  Epicardial fat should be excluded.  Challenging – when thickened visceral pericardium
  • 103.
    RV Function RV systolicfunction should be assessed by at least one or a combination of the following parameters: 1. TAPSE (Tricuspid Annular Plane Systolic Excursion) 2. DTI-Derived Tricuspid Lateral Annular Systolic Velocity S’ 3. FAC (fractional area change) 4. RV longitudinal strain 5. 3D EF 6. Right Index of Myocardial Performance (RIMP or MPI)
  • 104.
    RIMP (Right Indexof Myocardial performance) (Tei index)  assesses global RV function  requires beats with similar RR intervals  unreliable when RA pressure is elevated  IVCT, IVRT and ET from PW of TV inflow & RVOT, or DTI of lateral TV annulus (values differ by method) RIMP = (TCO – ET)/ET, where TCO is the TV closure to opening time RIMP >0.43 by PW Doppler & >0.54 by DTI s/o RV DYSFUNCTION. DTI – single beat recording, no need for R-R interval matching, which is needed in PW PW SPECTRAL DOPPLER DTI OF LATERAL TRICUSPID ANNULUS
  • 105.
    FAC  reflects bothlongitudinal & radial components of RV contraction  correlates with RV EF by CMR  does not include the contribution of RV outflow tract to systolic function • RV FAC % = EDA-ESA/EDAX100 • GLOBAL RV SYSTOLIC FUNCTION <35% FAC s/o RV SYSTOLIC DYSFUNCTION RV FOCUSED APICAL 4 CHAMBER VIEW
  • 106.
    RV 3D EF includes RVOT contribution to overall function  post cardiac surgery pts – conventional indices (TAPSE, S wave) no longer representative of RV function  slightly higher in women, because of smaller volumes  <45% s/o RV SYSTOLIC DYSFUNCTION  Limitation - load dependency, interventricular changes affecting septal motion, poor acoustic windows, & irregular rhythms
  • 107.
    TAPSE  predominantly RVlongitudinal function; good correlation with parameters estimating RV global systolic function  may over- or underestimate RV function due to cardiac translation  angle dependency  established prognostic value  Measure by M-MODE.  TAPSE <17 mm s/o RV SYSTOLIC DYSFUNCTION.
  • 108.
    DTI -derived tricuspidlateral annular systolic velocity S’  Longitudinal RV function, established prognostic value  may be inaccurate in post thoracotomy, pulmonary thromboendarterectomy or heart transplantation  angle dependent  <9.5 cm/sec on free wall s/o RVSD Peak systolic velocity of tricuspid Annulus by PW-DTI Easy, reproducible, prognostic value.
  • 109.
    RV longitudinal strain Less confounded by overall heart motion, but depends on RV loading conditions as well as RV size and shape  RV-focused view  Normal value is approximately -20%  AVERAGED over 3 segment of RV free wall. RV FOCUSED A4C
  • 110.
    Normal values forparameters of RV function
  • 111.
    LA AREA/ VOLUMEMEASUREMENTS • End-systole when the LA chamber is at its greatest (prior to MV opening) • Avoid foreshortening • Dedicated acquisition (apical) - maximize LA length & align true long axis of LA • For tracing area/volume, exclude confluences of PVs & LA appendage • AV interface represented by the mitral annulus plane
  • 112.
    LA Anterior-Posterior (AP) dimension •Should not be used as sole LA measurement (does not represent accurate LA size) • 2D measure preferred over M-mode • Perpendicular to long axis of LA posterior wall, Leading-leading (M-mode) or Inner-Inner (2DE) • Measured at the level of aortic sinuses
  • 113.
    LA Area • A4C& A2C • Base of LA should be at its largest • Trace LA inner border, excluding area under MV annulus, PVs and LA appendage
  • 114.
    LA Volume (Preferredover linear or area-length method)  Trace LA inner border, excl. area under MV annulus, PVs, and LA appendage from A4C & A2C views  Area-length technique: Length (L) measured from the shorter of the two long axes in 4C/2C views  Biplane summation of discs (preferred)
  • 115.
    CORRECT METHOD OFLINEAR MEASUREMENTS
  • 116.
    NORMAL VALUES –LA DIMENSIONS
  • 117.
    RA AREA &VOLUME MEASUREMENTS RA area • End-systole, at its greatest dimension, prior to TV opening • Dedicated right heart view (an A4C view that includes entire RA and is not foreshortened) • RA length should be maximized by alignment along the true long axis of RA • Base of the RA should be at its largest size • Planimetry - exclude area under TV annulus & confluences of RA appendage
  • 118.
    RA Volume (singleplane) • More robust and accurate • A4C dedicated right heart view • No standard orthogonal RA view - so a single-view area-length and/or disk summation technique should be used • Area-length method: Length performed at center of area under the TV annulus to the superior RA wall.
  • 119.
  • 120.
    Aortic Root • Maximaldiameter at the sinuses of Valsalva (PLAX) • Moving closer to sternum and/or a higher ICS allows better visual of ascending aorta • Measure in view that depicts maximum diameter, perpendicular to long axis aorta, and at end- diastole • Leading edge to leading edge for root & aorta • 2D measurements preferable to M-mode, (cardiac motion may result in changes in position of M-mode cursor AORTA
  • 121.
    Aortic annulus • Nota true or distinct anatomic structure (“virtual ring” defined by joining basal attachments of 3 aortic leaflets) • uppermost attachments of leaflets, in the shape of a crown, forms a true anatomic ring • Zoom mode, mid-systole, when annulus slightly larger and rounder (than diastole) • B/w hinge points of leaflets (usually hinge point of RCC & commissure b/w LCC/NCC) - inner edge to inner edge • Calcium protuberances are part of lumen, and excluded from diameter
  • 122.
    LVOT • ASE recommendsatleast 3 measurements of LVOT • Zoom mode, mid-systole, Inner to Inner edge, perpendicular to long axis of LVOT • The largest measurement is used for the continuity equation • In the absence of pre-valvular acceleration, the ASE states that it is acceptable to measure LVOT at the level of annulus • In AS, cursor is backed away from AV during LVOT velocity measurement (A5C), & LVOT measurement (PLAX) should be backed by the same distance from AV
  • 123.
    AORTIC ROOT DIMENSIONSIN NORMAL ADULTS
  • 124.
    INFERIOR VENA CAVA 2DEcho • Subcostal long axis view, with the patient supine • Open up IVC, so that diameter at fullest along the entire length • Inner-to-Inner Edge (I-I) • Measure perpendicular to the vessel, 1-2 cm from IVC-RA junction • DON’T measure at the junction of IVC & RA
  • 125.
    M-Mode (Assessing thecollapsibility/sniff test) • Excellent for degree of inspiratory collapse • Better interrogation over time (pre sniff, sniff and post sniff) in the same image • Often requires a brief sniff, as normal inspiration may not elicit this response
  • 126.
    • Based onIVC size (< or >2.1 cm) & collapsibility index (< or >50%): • When not to use IVC for RAP estimation? o Healthy young athletes may have dilated IVC in presence of normal pressures o IVC is commonly dilated and may not collapse in patients on ventilators RIGHT ATRIAL PRESSURE (RAP)
  • 127.