The document discusses different types of grids that can be used for desktop publishing layout design. It describes four main types of grids: 1) manuscript grids used for books and essays, 2) column grids used for magazines and newspapers, 3) modular grids used for more complex layouts, and 4) hierarchical grids used mainly for web design. It then provides details on the anatomy of grids, including columns, modules, margins, flow lines, spatial zones, and markers.