B) Based on the allele frequency for this trait in the population, what assumptions would you make about the genotype of each outsider in this family tree if you were expecting it to be a recessive trait? Explain your reasoning. C) You collect phenotypic data from the living family member and determine that the following family members have tooth agenesis Affected member of this family are: II2, II4, II7, II8, III2, III4, III5, III7, III8, IV1, IV2 Which, if any, modes of inheritance may be ruled out for this family? Briefly explain your reasoning for each mode you rule out (use table below). D) Are the two sets of twins in this family identical or fraternal twins? What is the basis of your answer? E) If III-2 and III-7 married and had a child, what is the probability that their child would have tooth agenesis? State the mode of inheritance that you think is most likely for this tree. Show your calculations based on that mode of inheritance. Mode of Inheritance: Probability:Rule out? (Yes or No)Rationaleautosomal dominantautosomal recessiveX-linked dominantX-linked recessive Solution A) The outsiders of the family tree are II-1, II-5, II-6, II-9, III-1 B) The genotype of outsiders are as under II-1, a carrier, because one of the offspring is affected (III-2). II-5, affected, because both of its offsprings are affected (III-4, III-5). II-6, normal, also not a carrier, because its offspring is normal (III-6). II-9, affected, because both of its offsprings are affected (III-7, III-8) III-1, affected, because both of its offsprings are affected (IV-1, IV-2). C) The mode of inheritance is not autosomal dominant, because the offspring of the affected parent (II-7) is normal. The mode of inheritance is outosomal recessive. Because the parents I-1, I-2 are carriers and offspring of the affected parent (II-7) is normal. The inheitance is not X-linked dominant nor X-linked recessive, because both male and female are affected. D) The two sets of twins in this family- one set is identical and other is fraternal twins Twins (II-1, II-2) are fraternal twins, because one is affeted (II-2) and other is unaffected (II-1). Twins (II-7, II-8) are identical twins, because both the twins are affected. E) If III-2 and III-7 married, their 100% probability that the child would have tooth agenesis. Because the inheritance is autosomal recessive and both are affected..

1. B) Based on the allele frequency for this trait in the population, what assumptions would you
make about the genotype of each outsider in this family tree if you were expecting it to be a
recessive trait? Explain your reasoning.
C) You collect phenotypic data from the living family member and determine that the following
family members have tooth agenesis
Affected member of this family are: II2, II4, II7, II8, III2, III4, III5, III7, III8, IV1, IV2
Which, if any, modes of inheritance may be ruled out for this family? Briefly explain your
reasoning for each mode you rule out (use table below).
D) Are the two sets of twins in this family identical or fraternal twins? What is the basis of your
answer?
E) If III-2 and III-7 married and had a child, what is the probability that their child would have
tooth agenesis? State the mode of inheritance that you think is most likely for this tree. Show
your calculations based on that mode of inheritance.
Mode of Inheritance:
Probability:Rule out? (Yes or No)Rationaleautosomal dominantautosomal recessiveX-linked
dominantX-linked recessive
Solution
A) The outsiders of the family tree are
II-1, II-5, II-6, II-9, III-1
B) The genotype of outsiders are as under
II-1, a carrier, because one of the offspring is affected (III-2).
II-5, affected, because both of its offsprings are affected (III-4, III-5).
II-6, normal, also not a carrier, because its offspring is normal (III-6).
II-9, affected, because both of its offsprings are affected (III-7, III-8)
III-1, affected, because both of its offsprings are affected (IV-1, IV-2).
C)
The mode of inheritance is not autosomal dominant, because the offspring of the affected parent
(II-7) is normal.
The mode of inheritance is outosomal recessive. Because the parents I-1, I-2 are carriers and
offspring of the affected parent (II-7) is normal.
The inheitance is not X-linked dominant nor X-linked recessive, because both male and female
are affected.
D) The two sets of twins in this family- one set is identical and other is fraternal twins

2. Twins (II-1, II-2) are fraternal twins, because one is affeted (II-2) and other is unaffected (II-1).
Twins (II-7, II-8) are identical twins, because both the twins are affected.
E) If III-2 and III-7 married, their 100% probability that the child would have tooth agenesis.
Because the inheritance is autosomal recessive and both are affected.