This document discusses how AWS can help improve manufacturing operations through digital transformation and industrial IoT. It begins by outlining key industry trends and challenges facing manufacturing, such as emerging markets, complex supply chains, demanding customers, and workforce issues. It then provides examples of how manufacturers are using AWS services like IoT, machine learning and analytics to gain insights from data, optimize operations, improve quality and efficiency, and protect intellectual property. Specific use cases discussed include predictive maintenance, quality control, and asset monitoring. The reference architecture shows how AWS services integrate with existing IT and OT systems to securely connect devices at the edge to applications in the cloud.