ATHEROSCLEROSIS
DEFINITION :
is a condition where the
arteries become narrowed
and hardened due to an
excessive build up of
plaque around the artery
wall. The disease disrupts
the flow of blood around
the body, posing serious
cardiovascular
complications.
PATHOGENESIS
Damage of endothelium
 LDL accumulation
 Platelet &monocyte activation
 Macrophages engulf lipids
foam cells
Smooth muscles
proliferation
CAUSES
 High BloodPressure
 High levels of cholesterol
 Smoking
 High levels of sugar in the blood
GROSS :
MICROSCOPIC PICTURE
COMPLICATIONS :
TREATMENT OF ATHEROSCLEROSIS
Lifestyle Changes
Medication
• Antiplatelet
• Atorvastatin
• (ACE) inhibitors
Surgery
PREVENTION
Diet
• olive oil
• avocados
• walnuts
• oily fish
• nuts
• seeds
Exercise
Stop smoking
Atherosclerosis

Atherosclerosis