Indigenous Australians and Pacific Islanders have faced numerous health challenges due to historical factors like colonization introducing new diseases, and more recently due to difficulties accessing appropriate healthcare services. Some key health issues include higher rates of diabetes, cardiovascular disease, and mental health problems. Both groups experience similar barriers like language and cultural differences, but Indigenous Australians face additional issues of racism, discrimination, and the legacy of policies like the Stolen Generations. Improving health requires culturally-sensitive care, education to increase health literacy, and addressing social determinants like employment and housing.