This document discusses the importance of quality systems and connectivity for decentralized HIV testing. It notes that point-of-care testing presents challenges for quality control compared to centralized laboratories due to harsher environments, less skilled operators, and fewer resources. However, connected diagnostic platforms can help by providing continuous quality monitoring, internal quality control, external quality assessment, and key performance/quality indicators. The document highlights a pilot project in Zimbabwe using an integrated laboratory network for automated quality monitoring and external quality assessment reporting. It concludes that connectivity is essential to ensure successful scale-up of testing and maximize return on investment as testing expands to more facilities.