Antidote
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Antidotes are drugs used to treat poisoning. They can be classified based on their mechanism of action as physiological, chemical, or mechanical antidotes. Physiological antidotes work by producing effects opposite to the poison. Chemical antidotes act by combining with the poison to change its chemical nature. Mechanical antidotes prevent absorption of the poison into the body.
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This document lists and describes 5 common experimental animals used in pharmacology: guinea pig, albino rat, albino mouse, rabbit, and frog. It provides details on each animal such as scientific name, physical characteristics, lifespan parameters, and their typical experimental uses. Guinea pigs are used to evaluate bronchodilators and local anesthetics. Albino rats are used in psychopharmacological and toxicological studies. Albino mice are used to study analgesics and chemotherapeutics. Rabbits are used in pyrogen testing and studying mydriatic and miotic drugs. Frogs are used to study drugs' effects on the heart and neuromuscular junction.
Introduction to experimental pharmacology
Experimental pharmacology is the branch of pharmacology that studies the effects of drugs on living organisms. It involves preclinical studies on animals to discover new drugs and determine their effects before clinical studies on humans. Preclinical studies include both in vivo experiments, which study drug effects on whole animals, and in vitro experiments, which isolate tissues and organs to study drug interactions outside of the body through dissection and isolation techniques.
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Antidote
- 1. ANTIDOTE Prepared by – Mr. Digambar C Jadhav Lecturer College of pharmacy, Paniv
- 2. LEARNING OUTCOMES After completion of this topic students will be able to :- 1. Define Antidote 2. Classify antidote 3. Explain mechanism of action of antidote
- 3. DEFINITION Antidote – “Antidote are the drugs which are used in the treatment of poisoning ” Poisoning – Poisoning means entry of poison inside the body. Poison – It is defined as any substance administered by any route of administration produces ill health, disease or death.
- 4. REFLECTION SPOT Que – What are the different route of administration through which poisoning may takes place ?
- 5. CLASSIFICATION Classification based on mechanism of action 1. Physiological antidote e.g – Sodium nitrite 2. Chemical antidote e.g – Sodium thiosulphate 3. Mechanical antidote e.g – Activated charcoal
- 6. MECHANISM OF ACTION 1. Physiological antidote :- They act by producing opposite effect to that of poison.
- 7. MECHANISM OF ACTION 2. Chemical antidote :- They act by combining with poison & changes chemical nature of poison.
- 8. MECHANISM OF ACTION 3. Mechanical antidote :- They act by preventing absorption of poison into the body.
- 9. Thank you