3. INTRODUCTION
GLP for animal facilities is intended to assure qualities
maintenance and safety of animal used in laboratory
studies while conducting biomedical and behavioral
research and testing of products
CPCSEA(Committee for the Purpose of Control and
Supervision on Experiment on Animal )
The most commonly used animals:-
Frog , Guinea Pig
Mouse , Rat ,
Rabbit , Monkey
Cat , Dog , Sheep
4. ANIMAL HOUSE DESIGNING
KEY COMPONENTS IN DESIGN
Animal holding rooms
Procedure rooms
Washing area
Storage
Waste area
Corridor
Furniture and equipment
Animal watering systems
6. ANIMAL HOUSE DESIGNING
Animal Holding Rooms :-
Building Material :- Moisture proof, Fire resistant ,
Seamless materials are most desirable for interior
surfaces
Corridor :- It should be wide enough to facilitate the
movement of personnel as well as equipment’s and
should be kept clean
Floors :- Floors should be smooth ,moisture proof , skid
proof,
7. ANIMAL HOUSE DESIGNING
Storage Area:-Separate storage area should be designed
for feed , bedding , cages and materials not in use .
Refrigerated storage is essential for storage of dead
animals and animal tissue waste.
Animal Room Doors:-Doors should be rust , vermin and
dust proof . They should fit properly within their frames
provided with an observation window. Rodent barrier
can be provided in the doors of the small animal
facilities.
8. ANIMAL HOUSE DESIGNING
Walls and Ceilings:- Walls should be free of cracks.
Temperature and humidity control:- Air conditioning is
an effective means of regulating these environmental
parameters for laboratory animals.
Power and Lighting:- Lighting system be installed that
provides adequate illumination while people are working
in the animal rooms and a lowered intensity of light for
the animals. Emergency power should be available in the
event of power failure.
9.
10. ANIMAL HOUSE DESIGNING
Noise Control:- Noise control is an important in
consideration in designing an animal facility. Concrete
wall are more effective than metal or plaster walls
containing noise because their density reduces sound
transmission.
Physical separation of animals by species is
recommended to prevent inter-species disease
transmission and to eliminate anxiety and possible
physiological and behavioral changes due to inter-
species conflict.
11. ANIMAL HOUSE DESIGNING
•
Change
/ Shower
Common
room
office store
Corridoor
Stock
Animal
Experimental
animal
Laboratory Breeding
Dirty Disposal Corridoor
Cleaning
Room
Disposal
13. FACTORS THAT INFLUENCE ANIMAL
RESEARCH
Animal Related Factors
Age Sex Reproductive status
Genetic make-up
Disease
Biological rhythms
Microbial flora
14. FACTORS THAT INFLUENCE ANIMAL
RESEARCH
Physical & Environmental Factors
Noise
Room Temperature
Lighting System
Relative humidity
Building
Fluid and Water
15. VETERINARY CARE
Animals should be observed regularly and problems of
animal health and behavior recorded & addressed
Diseased animals should be isolated from healthy ones
Personnel hygiene & Training of staff
Initial in-house training should be imparted to the staff
associated with animal facility
Appropriate & protective gears (gloves masks head
cover shoes
Personnel should have periodic medical checkups to
ensure their health status
16. RECRRD KEEPING
Animal facilities should have following records
Animal house plan
Name & addresses of the staff
Health record of staff
Training record of staff involved in animal care &
procedures
Animal stock procurement & supply register
Experimental records
Clinical record of sick animal & any treatment
administered
17. CONCLUSION
In the given study I have conclude that there are different
guidelines which must followed by us for better animal
studies & better result. There are so many parameters
which are affecting animal health & before going for
animal study all the factors should be studied for proper
designing of animal house.
18. REFERENCE
Hand book on care and management of laboratory and
pet animals by Y.S.Rajeshwari.
Animal house Breeding of experimental animals Jozsef
Kasazaki.
CPCSEA Guidlines report .
Turner JG, Bauer CA, Rybak LP. Noise in animal
facilities: why it matters. J Am Assoc Lab Anim Sci. Jan
2007;46(1):1s0-13.
Kállai László: Laborállat könyv, Royal Press Hungary
Kft, Budapest, 2003.