This document provides an overview of key differences between AngularJS 1.x and Angular 2.0. It discusses changes to change detection, routing, services, directives, transpilation to ES5, and dependency injection. Transpilation of Angular 2 code from ES6 to ES5 for browser compatibility is recommended using tools like Babel. Components, services, and directives are defined differently in Angular 2 compared to 1.x. Routing is now done at the component level rather than using routes.