This document summarizes a study on the use of the SyncardiaTAH device for long-term circulatory support. The study included 50 patients supported with the device for over 1 year. The primary diagnoses were dilated cardiomyopathy (23 patients), ischemic cardiomyopathy (15 patients), and other (9 patients). At 1 year post-implantation, the survival rate was 80%, with device failures and infections/hemorrhages being the primary causes of death. The conclusion is that the SyncardiaTAH device can reliably and effectively replace the entire heart for long-term support.