As healthcare reimbursement shifts from quantity to quality, particularly in Cardiology, the importance of capturing complete and accurate quality data metrics continues to grow. Yet, significant challenges exist in the collection, abstraction and submission of Cardiology quality data. Appropriately meeting these challenges can help your organization improve patient care, increase efficiency, enhance its reputation and maximize reimbursements.
Computer Vision Syndrome (CVS) is the general term used to describe a variety of vision related symptoms that may be aggravated by regular use of a computer for two or more hours a day
Computer Vision Syndrome (CVS) is the general term used to describe a variety of vision related symptoms that may be aggravated by regular use of a computer for two or more hours a day
Higher Education Compliance Survey Results: What Are Schools Really DoingSparkroom
Program Integrity regulations have led schools to change everything from marketing campaigns to internal policies. But with so much room for interpretation, it’s difficult to know what’s really necessary. Find out how schools are responding to the regulations, emerging best practices, and how your school can stay ahead of the compliance curve.
McKesson’s Quality Benchmarks Collaborative, a component of the McKesson Enterprise Intelligence portfolio, contains measures compiled as a by-product of the clinical quality measure reporting required by CMS under HITECH. Using McKesson Quality eMeasures as a foundation, the service enables subscribers to compare their results to other providers’ to understand their comparative performance. Learn more!
Using reference materials to meet validation & verification requirements for ...Candy Smellie
Bio-Specimens used in Molecular Diagnostics
Most clinical tissue samples are preserved in FFPE
FFPE samples are now being used for molecular diagnostic testing
FFPE based studies: every specimen is different in terms of % tumor contribution to the specimen and % mutation contribution to the tumor
External Quality Assessment Proficiency Testing Scheme
Therapeutic choices are made based upon these results
False positive and false negative results are detrimental to the patient
Validation occurs across multiple areas of the clinical laboratory. Validation can include equipment, reagents, operators, platforms. Two of the key areas are test and platform validation.
Test development includes:
Establishing protocol
Optimising performance
Determining pooling parameters
Using synthetic variants to compare tools and facilitate optimisation
Test validation includes:
Determine parameters
First tests developed carry highest validation requirements
Changes to tests must follow re-validation required against existing test
Platform validation
Cumulative performance data established
Determine confidence intervals
Track and validate software versions
Changes to platform must follow re-validation required against existing platform
Go Predictive Analytics, LLC is a premier data mining and predictive analytics consulting company. We remove the barriers that loom large with creating and deploying data mining solutions for high ROI.
Total Quality Management (TQM) by Dr Anurag YadavDr Anurag Yadav
Laboratory Total Quality Management, Concept of Laboratory errors, the quality control material, quality assurance program, factors affecting the quality of report, Steps in quality management, PDCA cycle, accuracy, precision, EQAS, IQAS, Proficiency testing.
the details are related to medical laboratory and help MBBS, MD, BSc MLT, MSc MLT, etc
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Higher Education Compliance Survey Results: What Are Schools Really DoingSparkroom
Program Integrity regulations have led schools to change everything from marketing campaigns to internal policies. But with so much room for interpretation, it’s difficult to know what’s really necessary. Find out how schools are responding to the regulations, emerging best practices, and how your school can stay ahead of the compliance curve.
McKesson’s Quality Benchmarks Collaborative, a component of the McKesson Enterprise Intelligence portfolio, contains measures compiled as a by-product of the clinical quality measure reporting required by CMS under HITECH. Using McKesson Quality eMeasures as a foundation, the service enables subscribers to compare their results to other providers’ to understand their comparative performance. Learn more!
Using reference materials to meet validation & verification requirements for ...Candy Smellie
Bio-Specimens used in Molecular Diagnostics
Most clinical tissue samples are preserved in FFPE
FFPE samples are now being used for molecular diagnostic testing
FFPE based studies: every specimen is different in terms of % tumor contribution to the specimen and % mutation contribution to the tumor
External Quality Assessment Proficiency Testing Scheme
Therapeutic choices are made based upon these results
False positive and false negative results are detrimental to the patient
Validation occurs across multiple areas of the clinical laboratory. Validation can include equipment, reagents, operators, platforms. Two of the key areas are test and platform validation.
Test development includes:
Establishing protocol
Optimising performance
Determining pooling parameters
Using synthetic variants to compare tools and facilitate optimisation
Test validation includes:
Determine parameters
First tests developed carry highest validation requirements
Changes to tests must follow re-validation required against existing test
Platform validation
Cumulative performance data established
Determine confidence intervals
Track and validate software versions
Changes to platform must follow re-validation required against existing platform
Go Predictive Analytics, LLC is a premier data mining and predictive analytics consulting company. We remove the barriers that loom large with creating and deploying data mining solutions for high ROI.
Total Quality Management (TQM) by Dr Anurag YadavDr Anurag Yadav
Laboratory Total Quality Management, Concept of Laboratory errors, the quality control material, quality assurance program, factors affecting the quality of report, Steps in quality management, PDCA cycle, accuracy, precision, EQAS, IQAS, Proficiency testing.
the details are related to medical laboratory and help MBBS, MD, BSc MLT, MSc MLT, etc
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
American College of Cardiology - Cardiovascular Summit 2013
1. ACC Reporting: Overcoming Data Management
Challenges
Dr. Saji Salam MD, MBA
Director of Clinical Informatics
David LaMotte BCS
Senior Product Manager, PVMD Cardiology
2. Forces of Change
■ Practice Integration
■ Reimbursement Scrutiny
■ 24% of denials related to MS-DRG 247
■ Top reason: Documentation did not substantiate
the need for admission
■ Appropriate Use Criteria
Bottom Line:
Quality documentation and reporting is becoming critical
3. 0%
10%
20%
30%
40%
50%
60%
70%
90%
100%
80%
N=205
79%
Maximize reimbursement:
47%
75%
Improve patient satisfaction:
42%
67%
Admin
Reduce costs in the cath lab:
41%
Cath Lab Goals
65%
Report quality measures:
48%
Physician
62%
Achieve meaningful use:
31%
59%
Prepare/prevent RAC audits:
31%
Improve care coordination/ 57%
communication with hospital: 29%
Improve care coordination/ 56%
communication with referring
physicians: 27%
Monitoring and improving 53%
appropriate use measures: 40%
Improve integration of 52%
technology within cath lab: 32%
5. Drivers for data management
■ Quality is priority
■ Reimbursement
■ AUC criteria
■ Audits
■ Meaningful use
■ Patient satisfaction
■ Others…
6. Current State
Procedure
Office Report
Note
EMR
Hemo NCDR
Billing
7. Case Studies
Case 1: Stand-alone, for-profit hospital in the North East
• Using procedure documentation system for nearly all procedures
• One full-time (PhD) and two part-time dedicated to reporting
Case 2: Health System in the Upper Midwest
• Using procedure documentation for majority of cases
• Two full-time and one part-time nurse dedicated to reporting
Case 3: Large health system in a major city
• No procedure documentation system; use dictation
• Uses two different systems for Echo and Nuke
• 3 full-time nurses dedicated to reporting
8. Summary of Issues
■ Missing data
■ Incomplete / inaccurate data
■ Inconsistent data
■ Redundant data entry
Result: Large effort, sometimes 3 hours per case .
Result: Backlog of quality projects.
9. Challenges
■ Technical
• Number of Data Sources
• Integration
• Source of Truth?
• IT Capacity
■ Human
• Conflicting Perspectives
• Process Inertia
• Attitudes Matter
■ Financial
13. Road map
• Current Process
• Costs / Opportunities
• Prioritize
• Engage leadership and stakeholders
• Sell to key stakeholders and
policymakers
• Process changes
• Technology changes
• Integration changes
Editor's Notes
Disparate systemsLimited integration among systemsManual data collection and reporting Big problems:Office NoteProcedure NoteReporting SystemSmaller problem:EMR black hole
Multiple data sourcesInconsistentUnavailableMultiple points of transcriptionError proneResource intensiveData collection staff make conservative guesses.
Asked them why it took so long.Needed to hunt for dataReconcile different dataCompensate for missing dataManual entry
Different nomenclaturesWho judges between conflicting elements? Example: (maybe % stenosis or lesion length)HumanWho enters the data? From whom? Number of key stakeholders that don’t want additional work.Problem? What problem? The process works!I’m not a stenographer! I have more important things to do!Change is expensive.
What do we want?Trustworthy data coming into the process.Doctors to use the procedure documentation system most of the time.Data as complete as we can make it.Minimize redundancy.Data to flow between departments and components.Minimize the amount of manual entry.
Talk to the project plan, key stakeholders and actions taken to address the challengesQuality staff will get “office note” with key clinical elements and enter them into the hemodynamic systemTemplate in hemodynamic system created by internal staff (no vendor involvement)Pre-procedure nurse will validate with patientEnhancing the integration from hemodynamic system to procedure documentation to include that dataImplementing a reporting system that pre-fills data from procedure documentationMaintaining policy of the EMR as repository of most current informationChanges a majority of work from data entry to validation, thereby freeing quality staff for project backlogImproves the completeness and quality of pre-procedure data, thereby improving careMakes data needed for diagnostic appropriateness available before the procedure is performed
Document your current process, with challenges faced by each roleIdentify the opportunities in your specific situationIdentify the value of overcoming eachGo after the highest value first – Watch out for missing requirements! (enabling technology)Identify key stakeholders and sellSet up a communication plan and follow it