1) The document discusses the "All-on-4" technique for placing four dental implants (two tilted posteriorly and two anterior) to support a fixed prosthesis in edentulous maxilla or mandible.
2) Previous studies have shown this technique to be predictable and successful with high implant survival rates and minimal bone loss.
3) Tilting the posterior implants provides benefits like avoiding anatomical structures and improving prosthesis support.
Full body is the most of I don't have a lot more then I have been on my phone is a new one number and my heart is a new phone is it possible to be fine and I have a good day of the year and I am a good time with my family and I have to do not know what you do not know how to do with your family is a good day of
Full body is the most of I don't have a lot more then I have been on my phone is a new one number and my heart is a new phone is it possible to be fine and I have a good day of the year and I am a good time with my family and I have to do not know what you do not know how to do with your family is a good day of
An Evaluation of Short Term Success and Survival Rate of Implants Placed in F...DrHeena tiwari
An Evaluation of Short Term Success and Survival Rate of Implants Placed in Fresh Extraction Socket Post Prosthetic Rehabilitation- A Prospective Study
Journal Club On Pre-extractive Interradicular Implant Bed Preparation: Case P...Shilpa Shiv
Journal Club On Pre-extractive Interradicular Implant Bed Preparation: Case Presentations of a Novel Approach to Immediate Implant Placement at Multirooted Molar Sites, IJPRD 2013.
ABSTRACT- Background: Femoral shaft fractures are most common fractures in paediatric orthopaedic age
group. There are distinct methodologies to treat them. Elastic stable intramedullary nailing is one in every of them and a
longtime and reliable methodology for treating these fractures.
Aims: To evaluate the clinical, functional and radiological outcome of intramedullary fixation of displaced fracture
shaft femur in skeletally immature children using titanium elastic intramedullary nails.
Material and Methods: 65 Femoral shaft fracture in 60 children aged 6-14 years were fixed with titanium
intramedullary elastic nail under image intensifier control between July 2013 and June 2017.Two nails of proper and
equal diameter were used for fracture fixation. No external splint was used after surgery. Outcomes assessed on the
basis of Flynn et al scoring criterion.
Results: All patients achieved complete healing at a mean of 9.5 weeks. 51 fracture reduced by closed means but 14
needs open reduction. Common size of elastic nail used was 3mm. no major complication was recorded all were minor
and can be taken care off. Most common was entry site skin irritation recorded in 10 patients. 90% had excellent result
and 10% had satisfactory.
Conclusion: Elastic stable intramedullary nailing is the method of choice for the Femoral shaft fracture in paediatric
patients, because it is minimally invasive and provide six point fixation and shows very good functional and cosmetic
result. It allows early ambulation and shorter hospital stay and higher parent satisfaction. ESIN also provide flexural,
translational and rotational stability as well.
Key-words- Elastic stable intramedullary nailing (ESIN), Titanium elastic nail (TEN), Femoral shaft fracture,
Paediatric
Patients with resorbed ridges often have difficulty retaining conventional dentures. An implant supported overdenture is a good alternative treatment to a conventional denture for patients with complaints about the retention and stability of their removable complete denture. . These complaints more often have to do with the mandibular than the maxillary denture. Implantsupported overdentures offer better results in the mandible than in the maxilla. The two implant overdenture in the mandible has since become standard for edentulous patients. This article describes a clinical procedure for an implant supported mandibular overdenture.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
An Evaluation of Short Term Success and Survival Rate of Implants Placed in F...DrHeena tiwari
An Evaluation of Short Term Success and Survival Rate of Implants Placed in Fresh Extraction Socket Post Prosthetic Rehabilitation- A Prospective Study
Journal Club On Pre-extractive Interradicular Implant Bed Preparation: Case P...Shilpa Shiv
Journal Club On Pre-extractive Interradicular Implant Bed Preparation: Case Presentations of a Novel Approach to Immediate Implant Placement at Multirooted Molar Sites, IJPRD 2013.
ABSTRACT- Background: Femoral shaft fractures are most common fractures in paediatric orthopaedic age
group. There are distinct methodologies to treat them. Elastic stable intramedullary nailing is one in every of them and a
longtime and reliable methodology for treating these fractures.
Aims: To evaluate the clinical, functional and radiological outcome of intramedullary fixation of displaced fracture
shaft femur in skeletally immature children using titanium elastic intramedullary nails.
Material and Methods: 65 Femoral shaft fracture in 60 children aged 6-14 years were fixed with titanium
intramedullary elastic nail under image intensifier control between July 2013 and June 2017.Two nails of proper and
equal diameter were used for fracture fixation. No external splint was used after surgery. Outcomes assessed on the
basis of Flynn et al scoring criterion.
Results: All patients achieved complete healing at a mean of 9.5 weeks. 51 fracture reduced by closed means but 14
needs open reduction. Common size of elastic nail used was 3mm. no major complication was recorded all were minor
and can be taken care off. Most common was entry site skin irritation recorded in 10 patients. 90% had excellent result
and 10% had satisfactory.
Conclusion: Elastic stable intramedullary nailing is the method of choice for the Femoral shaft fracture in paediatric
patients, because it is minimally invasive and provide six point fixation and shows very good functional and cosmetic
result. It allows early ambulation and shorter hospital stay and higher parent satisfaction. ESIN also provide flexural,
translational and rotational stability as well.
Key-words- Elastic stable intramedullary nailing (ESIN), Titanium elastic nail (TEN), Femoral shaft fracture,
Paediatric
Patients with resorbed ridges often have difficulty retaining conventional dentures. An implant supported overdenture is a good alternative treatment to a conventional denture for patients with complaints about the retention and stability of their removable complete denture. . These complaints more often have to do with the mandibular than the maxillary denture. Implantsupported overdentures offer better results in the mandible than in the maxilla. The two implant overdenture in the mandible has since become standard for edentulous patients. This article describes a clinical procedure for an implant supported mandibular overdenture.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
ALL ON 4.pptx
1. VIABILITY OF “ALL ON 4” TECHNIQUE IN
MAXILLA & MANDIBLE WITH ATROPHIC
POSTERIOR BONE
Presented by: Guided By: Dr AJAZ AHMAD SHAH
Dr Mohd Younis Prof and Head OMFS, GDC,
Srinagar
Co Guided By: Dr SHAHID
HASSAN
Assistant Prof. Department of OMFS
Co Guided By: Dr. Shujah Hussain
Consultant Department of OMFS
2. The “All-on-4” treatment concept was Brain child of Paulo Malo and
meld an immediately loaded full arch fixed prosthesis anchored with
four implants in mandible or maxilla. Wielding immediate function
full arch prostheses in the mandible and maxilla has been proved as a
predictable and successful procedure based on long-term results.
3. The “All-on-4” concept utilises:
• Two tilted posterior implants.
• Two axially orientated implants in the anterior region
implants conventionally have been placed axially, along the
long axis of the tooth to transmit forces axially down the
implant.
In the completely edentulous jaw, more often there is
insufficient vertical bone height because of bone
resorption in the posterior regions.
This can be due to bone resorption after extraction and the
immediacy of the inferior alveolar nerve in the mandible
and the maxillary sinus in the maxilla.
4. Previously, there was a necessity for bone grafting to
augment the bone in posterior regions to build vertical
height for adequate implant length, adding notable
time and cost to the procedures.
5.
6. Benefits of Angled posterior implants:
• Help avoid relevant anatomical structures and
can be anchored in better quality anterior bone
• Offer improved support of the prosthesis by
reducing cantilevers
• Reduce the need for bone grafting by
maximizing the use of available bone
Final restoration:
• Full-arch restoration with only 4 implants
• Fixed and removable final prosthetic solutions
Efficient Treatment Flow:
• Immediately loaded for shorter treatment times
and improved patient satisfaction
7.
8.
9. Ethical clearance - Institutional review board of
Govt. Dental College, Srinagar.
Informed/ Written consent will be obtained
10. This study is proposed to include 10 patients with
complete edentulous arches visiting the department of
Oral & Maxillofacial Surgery “Govt. Dental College,
Srinagar.” And Hospital.
11. Inclusion criteria:
Need for complete rehabilitation of complete maxilla
or mandible or both
ASA –I, ASA-II, ASA-III
Sufficient bone for 4 implants atleast 10 mm in length
Acceptable oral hygiene
12. 1. Previous history of head and neck irradiation
2. Patient not willing to be part of study
13.
14. Surgical procedures will be performed under local anaesthesia
(2%lignocaine with 1:80,000 adrenaline). Antibiotics to be given 1
hour prior to.
In edentulous arches, incisions will made on the alveolar crest, from
the first molar on the contralateral side with bilateral incisions.
Periosteal reflection on lingual and buccal surfaces will carried out,
crestal shaving of bone will be carried out in cases of crestal
irregularities
The most posterior implants are placed tilted distally at an angle
about 30 to 35 degrees relative to occlusal plane. The tilted implant
placement is assisted by a special guide.
The guide is placed into a 2 mm osteotomy made at the midline of
the jaw
Implant insertion follows standard procedures. Usually the osseous
receptor sites are under prepared in order to obtain a torque of more
than 30 NCM for the final seating of the implant. The implant neck
will be positioned at bone level, with bicortical anchorage whenever
possible.
16. In the mandible, a mucoperiosteal flap is raised using a
crestal incision extending from the first molar to first
molar.
Vertical releasing incision are to be avoided to prevent
damage to the mental nerve
2 distal implants will be inserted just anterior to the
foramina and the loop of the mental nerve. These implants
will be tilted distally about 30 degree relative to occlusal
plane. These posterior implants typically emerge at the
second premolar position.
The additional 2 most anterior implants follow the jaw
anatomy
17.
18. In the maxilla, a mucoperiosteal flap is raised along the rest of
the ridge with 2 relieving incisions performed on the buccal
aspect in the first molar area.
The posterior implant tilting allows a position shift on the
implant head from a vertically placed implant in the canine or
first premolar region to a tilted implant in the second premolar
or first molar region.
The 30 degree angulated abutments are placed on the implant,.
The anterior implants are oriented vertically by a guide pin that
replaces the edentulous guide.
The anterior position must be selected carefully to avoid conflict
with the apex of the tilted posterior implant, which normally
reach the canine area. The anterior implants are placed in lateral
or central incisor positions.
21. 1.Clinical implant mobility scale (Misch): The
Misch mobility scale will be used to assess implant
mobility by means of two rigid instruments.
The scale is as follows:
0 = absence of clinical mobility under a 500-g load in
any direction;
1 = slight detectable horizontal movement;
2 = moderate visible horizontal mobility up to 0.5 mm;
3 = severe horizontal movement >0.5 mm;
4 = visible moderate to severe horizontal and any
visible vertical movement.
22. 2. 2. Crestal bone height :The marginal bone levels,
to be evaluated on periapical or panoramic
radiographs, to be registered at the last follow-up visit
within the study time.
3. Implant Survival
23. Paulo Malo, Bo Rangert, Miguel Nobre; in 2003 conducted a clinical study
including 44 patients with 176 immediately loaded implants, placed in the
anterior region, supporting fixed complete – arch mandibular prosthesis in
acrylic. 5 immediately loaded implants failed in 5 patients before the 6th
month follow up, giving a cumulative survival rates of 96.7 and 98.2% for
development and routine groups. The prosthesis survival rate was 100% and the
average bone resorption was low.3
Paulo Maló, Bo Rangert, Miguel Nobre, in 2005 described a study to evaluate a
protocol for immediate function (within 3 hours) of four implants(All-on-4,
Nobel Biocare AB, Göteborg, Sweden) supporting a fixed prosthesis in the
completely edentulous maxilla. retrospective clinical study included 32
patients with 128 immediately loaded implants supporting fixed complete-arch
maxillary all-acrylic prostheses. A specially designed surgical guide was used to
facilitate implant positioning and tilting of the posterior implants to achieve
good bone anchorage and large interimplant distance for good prosthetic
support. Follow-up examinations were performed at 6 and 12 months.
Radiographic assessment of the marginal bone level was performed after 1 year
in function. Three immediately loaded implants were lost in three
patients,giving a 1-year cumulative survival rate of 97.6%.The marginal bone
level was, on average, 0.9 mm (SD 1.0 mm) from the implant/abutment
junction after 1 year.4
24. Paulo Maló, Miguel de AraújoNobre, Ulrika Petersson, StinaWigren, in
2006 described a study to retrospectively evaluate the clinical performance of a
novel implant design in the rehabilitation of completely edentulous jaws and in
combination with an immediate function protocol. Forty-six consecutive
patients received 189 study implants (NobelSpeedyTM concept implant, Nobel
Biocare AB, Göteborg, Sweden) supporting 53 full-arch all-acrylic prostheses
(44 maxilla, 9 mandible). The majority (66%) of the reconstructions were
supported by four implants, of which the two posterior implants were tilted.
All patients were followed for a minimum of 1 year. Radiographic assessment of
the marginal bone level was performed. Two implants were lost in two patients,
rendering a 1-year cumulative clinical survival rate of 98.9%. The marginal
bone level was, on average, situated 1.2 ± 0.7 mm below the implant-abutment
interface after 1 year of loading. Good soft tissue health and overall esthetic
outcome was reported.5
25. Leonard Krekmanow, Mikael Kahn, Bo Rangret, Hakan
Lindstrom; in 2000 came up with a new technique of posterior
Implant Placement by angulating the maxillary posteriors to 30-35
degree, mandibular posteriors to 25-35 degree. 47 patients were treated
with tilted implants. They were followed for 40 months (mandible) and
53 months (maxilla). Paresthesias of the mental nerve was observed on
4 sides during first 2-3 weeks after implant placement.
This new technique had benefits of decreased Mental nerve
paresthesis.6
Patrick. K. Chu; in 2010 described a case report where he has placed “All-on-
4” system of Implants in a 65 year old male patient partially edentulous in both
maxilla and mandible with advanced periodontitis and excessive mobility of
the remaining teeth. Dentures were pre made and holes were drilled according
to the surgical guide and were immediately given just after the treatment.7
26. 1. Maló P, Rangert B, Nobre M. “All‐on‐Four” immediate‐function concept with
Brånemark System® implants for completely edentulous mandibles:
aretrospective clinical study. CLIN IMPLANT DENT R. 2003 Mar;5:2-9
2. Maló P, Rangert B, Nobre M. All‐on‐4 immediate‐function concept with
Brånemark System® implants for completely edentulous maxillae: a 1‐year
retrospective clinical study. CLIN IMPLANT DENT R. 2005 Jun;7:s88-94.
3. Maló P, De AraújoNobre M, Petersson U, Wigren S. A pilot study of complete
edentulous rehabilitation with immediate function using a new implant
design: case series. CLIN IMPLANT DENT R. 2006 Dec;8(4):223-32.
4. Leonard Krekmanov DS, Kahn M, Rangert B, Eng M, Lindström H. Tilting of
posterior mandibular and maxillary implants for improved prosthesis support.
Int J Oral Maxillofac Implants. 2000 May;15(3).
5. Patrick.K.Chu. A case study: The All- on- 4 Treatment Concept
usingBiohorizons Tapered Internal Implants. Clin Oral Implants Res. Fall 2010;
Vol1 No 3.