Addison's disease is a disorder where the adrenal glands do not produce enough cortisol and often aldosterone. It occurs in about 1 in 100,000 people and equally affects both sexes. Primary Addison's disease is often caused by an autoimmune reaction where the immune system attacks the adrenal glands. Secondary Addison's disease can be caused by tumors, medications, genetics, or traumatic brain injury. Symptoms include extreme fatigue, weight loss, dark skin, low blood pressure, and low blood sugar. Diagnosis involves blood tests to check electrolyte and hormone levels and imaging to examine the adrenal glands. Treatment consists of hydrocortisone and fludrocortisone pills to