THIS IS A CASE BASED SLIDE PRESENTATION OF ACUTE LEUKEMIA INCLUDIND BOTH ACUTE MYELOID LEUKEMIA AND ACUTE LYMPHOID LEUKEMIA

1. CASE
DISCUSSION
PRESENTOR-DR. AMANI MUTAKANI
MODERATOR-DR. SONAL MESHRAM

2. CASE-1
A 4 YEAR MALE PRESENTED WITH COMPLAINTS OF RECURRENT
SORE THROAT AND COUGH. HIS MOTHER EXPLAINS UNUSUAL LISTLESSNESS
AND ANOREXIA. ON EXAMINATION, SEVERAL BRUISES PRESENT ON LEGS, ARMS,
AND ONE ON HIS BACK. BLOOD TEST WAS ADVISED AND PATIENT KEPT ON
ANTIBIOTICS. TEST RESULTS INDICATES LOW HB LEVEL, THROMBOCYTOPENIA
AND HIGH WBCS. PERIPHERAL SMEAR PROVIDED FOR EXAMINATION

3. 40x
RBC- Normocytic to microcytic, moderate hypochromic.

4. WBC
TLC – 1,20,000/CUMM
DLC – LYMPHOBLAST -82%,
POLYMORPHS – 3%
LYMPHOCYTES -12%
EOSINOPHILS-1%
MONOCYTE-2%
PLATELET COUNT – DEPLETED
NO HEMOPARASITE.
100x

5. Hand mirror cell
100x

6. Blasts cells – Round cells having scant cytoplasm
with high N:C ratio, coarse chromatin and 1-2 nucleoli
100x
Impression – Acute leukemia favouring Acute
lymphoblastic leukemia

7. CASE-2
A 45 YEAR FEMALE PRESENTED WITH FEVER, FATIGUE,
BONE PAIN AND BLEEDING GUMS. ON EXAMINATION,
STERNAL TENDERNESS NOTED. LAB FINDINGS – HB 8
GM/DL, TLC – 1,00,000/CUMM, PLATELET – 40,000/CUMM

8. RBC – Normocytic to microcytic, moderate to sever
hypochromic, occasional Nrbc +.
40x

9. WBC
TLC – 1,00,000/CUMM
DLC – MYELOBLAST – 92%,
POLYMORHS-4%
LYMPHOCYTES-2%
EOSINOPHILLS – 1%
MONOCYTE – 1%
PLATELET COUNT – DEPLATED
NO HEMOPARASITE.
100x

10. Blast cells -Round cells having scant to moderate amount of
basophilic cytoplasm and granules with high N:C ratio, delicate
chromatin and 3-5 nucleoli.
Impression – Acute leukemia favouring Acute myeloblastic leukemia.
100x 100x

11. THANK YOU