This document discusses accelerating mission critical workloads by migrating them from legacy and proprietary systems to open standard x86 platforms based on Intel Xeon processors. It provides an overview of how Intel is enabling this transition through improved performance, reliability, and security features in recent Xeon generations, as well as growing ecosystem support. Analyst reports and customer quotes are presented showing the migration of mission critical workloads from RISC/UNIX platforms to Xeon, driven by lower costs and comparable capabilities.