ANEMIA
Ancient Greek: anaimia,meaning lack of blood . Reduction in oxygen carrying capacity of blood due to decreased Hb,
PCV & total RBCs count below the normal is known as Anemia.
Classification of anemia
1. Morphological classification
2. Aetiological classification.
3.
CAUSE OF ANAEMIA
Blood Loss :
1. Acute ( Accident, injury, surgery , gastrointestinal bleeding, hematuria )
2. Chronic ( Bleeding from Ulcer, GI cancer, hook worm infection, prolong vaginal bleeding )
Anemia due to increase RBCs destruction ( Hemolytic anemia )
S.N Extrinsic defect of RBC (Extra Corpuscular ) Intra-corpuscular defect
( Hereditary defect )
1. Auto immune hemolytic anaemia Haemoglobinopathies(abnormal
Hb)
2. Infection e.g. protozoa(malaria) , bacteria(clostridium ),
Viral(infectious mononucleosis)
G6PD deficiency
3. Certain chemical & drugs ( lead, benzene, venom ,
chloramphenicol )
Thalassemia , Spherocytosis
4. Physical agents : ( heat, burn, UV ray ,) PNH( paroxysmal nocturnal
haemoglubinuria )
4.
1. Disturbance ofbone marrow function due to deficiency of :( iron, Vit. B12 , folic acid
)
2. Depression in erythropitic activity cause aplastic anaemia .
3. Anemia due to chronic renal failure and liver cirrhosis.
4. Infiltration of bone marrow e.g. multiple myeloma .
5. Endocrine abnormally for e.g. hypo & hyper thyroidism.
6. Congenital diserythropoitic anemia .
Causes of impaired RBC production: