SlideShare a Scribd company logo
1 of 2
Download to read offline
A bacterial pathogen is usually defined as any bacterium that has the capacity to cause disease.
Its ability to cause disease is called pathogenicity.
Virulence provides a quantitative measure of the pathogenicity or the likelihood of causing
disease.
Virulence factors refer to the properties (i.e., gene products) that enable a microorganism to
establish itself on or within a host of a particular species and enhance its potential to cause
disease.
Virulence factors include bacterial toxins, cell surface proteins that mediate bacterial attachment,
cell surface carbohydrates and proteins that protect a bacterium, and hydrolytic enzymes that
may contribute to the pathogenicity of the bacterium.
Virulence factors help bacteria to
(3) evade host defenses.
TYPES OF VIRULENT FACTORS and THEIR ROLES:
The following are types of virulence factors:
Adherence Factors: Many pathogenic bacteria colonize mucosal sites by using pili (fimbriae) to
adhere to cells.
Invasion Factors: Surface components that allow the bacterium to invade host cells can be
encoded on plasmids, but more often are on the chromosome.
Capsules: Many bacteria are surrounded by capsules that protect them from opsonization and
phagocytosis.
Endotoxins: The lipopolysaccharide endotoxins on Gram-negative bacteria cause fever, changes
in blood pressure, inflammation, lethal shock, and many other toxic events.
Exotoxins: Exotoxins include several types of protein toxins and enzymes produced and/or
secreted from pathogenic bacteria. Major categories include cytotoxins, neurotoxins, and
enterotoxins.
Siderophores: Siderophores are iron-binding factors that allow some bacteria to compete with the
host for iron, which is bound to hemoglobin, transferrin, and lactoferrin.
Solution
A bacterial pathogen is usually defined as any bacterium that has the capacity to cause disease.
Its ability to cause disease is called pathogenicity.
Virulence provides a quantitative measure of the pathogenicity or the likelihood of causing
disease.
Virulence factors refer to the properties (i.e., gene products) that enable a microorganism to
establish itself on or within a host of a particular species and enhance its potential to cause
disease.
Virulence factors include bacterial toxins, cell surface proteins that mediate bacterial attachment,
cell surface carbohydrates and proteins that protect a bacterium, and hydrolytic enzymes that
may contribute to the pathogenicity of the bacterium.
Virulence factors help bacteria to
(3) evade host defenses.
TYPES OF VIRULENT FACTORS and THEIR ROLES:
The following are types of virulence factors:
Adherence Factors: Many pathogenic bacteria colonize mucosal sites by using pili (fimbriae) to
adhere to cells.
Invasion Factors: Surface components that allow the bacterium to invade host cells can be
encoded on plasmids, but more often are on the chromosome.
Capsules: Many bacteria are surrounded by capsules that protect them from opsonization and
phagocytosis.
Endotoxins: The lipopolysaccharide endotoxins on Gram-negative bacteria cause fever, changes
in blood pressure, inflammation, lethal shock, and many other toxic events.
Exotoxins: Exotoxins include several types of protein toxins and enzymes produced and/or
secreted from pathogenic bacteria. Major categories include cytotoxins, neurotoxins, and
enterotoxins.
Siderophores: Siderophores are iron-binding factors that allow some bacteria to compete with the
host for iron, which is bound to hemoglobin, transferrin, and lactoferrin.

More Related Content

Similar to A bacterial pathogen is usually defined as any bacterium that has th.pdf

محاضرة اولى مناعة innate (1).pptx
محاضرة اولى مناعة innate (1).pptxمحاضرة اولى مناعة innate (1).pptx
محاضرة اولى مناعة innate (1).pptx
NationalSportforallv
 
2_2019_10_26!04_54_11_PM.ppt
2_2019_10_26!04_54_11_PM.ppt2_2019_10_26!04_54_11_PM.ppt
2_2019_10_26!04_54_11_PM.ppt
Imtiyaz60
 

Similar to A bacterial pathogen is usually defined as any bacterium that has th.pdf (20)

Bacterial Virulence Factors in Periodontology
Bacterial Virulence Factors in PeriodontologyBacterial Virulence Factors in Periodontology
Bacterial Virulence Factors in Periodontology
 
Bacterial virulence
Bacterial virulenceBacterial virulence
Bacterial virulence
 
Microbial_Pathogenicity.pdf
Microbial_Pathogenicity.pdfMicrobial_Pathogenicity.pdf
Microbial_Pathogenicity.pdf
 
RED COMPLEX ORGANISMS.docx
RED COMPLEX ORGANISMS.docxRED COMPLEX ORGANISMS.docx
RED COMPLEX ORGANISMS.docx
 
Microbial Pathogenicity.pptx
Microbial Pathogenicity.pptxMicrobial Pathogenicity.pptx
Microbial Pathogenicity.pptx
 
Role of bacterial organelles in virulence
Role of bacterial organelles in virulenceRole of bacterial organelles in virulence
Role of bacterial organelles in virulence
 
1محاضرة اولى مناعة innate 1.pptx
1محاضرة اولى مناعة innate 1.pptx1محاضرة اولى مناعة innate 1.pptx
1محاضرة اولى مناعة innate 1.pptx
 
4 bacterial infection and pathogenesis
4  bacterial infection and pathogenesis4  bacterial infection and pathogenesis
4 bacterial infection and pathogenesis
 
محاضرة اولى مناعة innate (1).pptx
محاضرة اولى مناعة innate (1).pptxمحاضرة اولى مناعة innate (1).pptx
محاضرة اولى مناعة innate (1).pptx
 
"Bio - Warfare During Host Pathogen Interactions in Indigenous Crop Plants" b...
"Bio - Warfare During Host Pathogen Interactions in Indigenous Crop Plants" b..."Bio - Warfare During Host Pathogen Interactions in Indigenous Crop Plants" b...
"Bio - Warfare During Host Pathogen Interactions in Indigenous Crop Plants" b...
 
Normal Flora
Normal FloraNormal Flora
Normal Flora
 
defence mechanisin chapter 5-OBU.pptx
defence mechanisin    chapter 5-OBU.pptxdefence mechanisin    chapter 5-OBU.pptx
defence mechanisin chapter 5-OBU.pptx
 
Antibiotic resistance: From a broader perspective
Antibiotic resistance: From a broader perspectiveAntibiotic resistance: From a broader perspective
Antibiotic resistance: From a broader perspective
 
2_2019_10_26!04_54_11_PM.ppt
2_2019_10_26!04_54_11_PM.ppt2_2019_10_26!04_54_11_PM.ppt
2_2019_10_26!04_54_11_PM.ppt
 
Host pathogen interactions
 Host pathogen interactions Host pathogen interactions
Host pathogen interactions
 
Medical Microbiology
Medical MicrobiologyMedical Microbiology
Medical Microbiology
 
Paraprotex
ParaprotexParaprotex
Paraprotex
 
PATHOGENESIS
PATHOGENESISPATHOGENESIS
PATHOGENESIS
 
Bacterial-Pathogenesis.pdf
Bacterial-Pathogenesis.pdfBacterial-Pathogenesis.pdf
Bacterial-Pathogenesis.pdf
 
An Overview of Immunity to Viruses, Bacteria, Fungi and Ptozoans
An Overview of Immunity to Viruses, Bacteria, Fungi and PtozoansAn Overview of Immunity to Viruses, Bacteria, Fungi and Ptozoans
An Overview of Immunity to Viruses, Bacteria, Fungi and Ptozoans
 

More from aquastore223

1. How new modern materials prompted changes in architecture in the .pdf
1. How new modern materials prompted changes in architecture in the .pdf1. How new modern materials prompted changes in architecture in the .pdf
1. How new modern materials prompted changes in architecture in the .pdf
aquastore223
 
c++ code for a Median of Integer Stream from Text File program#.pdf
 c++ code for a Median of Integer Stream from Text File program#.pdf c++ code for a Median of Integer Stream from Text File program#.pdf
c++ code for a Median of Integer Stream from Text File program#.pdf
aquastore223
 
Sodium hydroxide, also known as lye and caustic s.pdf
                     Sodium hydroxide, also known as lye and caustic s.pdf                     Sodium hydroxide, also known as lye and caustic s.pdf
Sodium hydroxide, also known as lye and caustic s.pdf
aquastore223
 
The molecular orbital (MO) theory is a way of loo.pdf
                     The molecular orbital (MO) theory is a way of loo.pdf                     The molecular orbital (MO) theory is a way of loo.pdf
The molecular orbital (MO) theory is a way of loo.pdf
aquastore223
 
Unfortunately several cancers are not predictable with simple tests .pdf
Unfortunately several cancers are not predictable with simple tests .pdfUnfortunately several cancers are not predictable with simple tests .pdf
Unfortunately several cancers are not predictable with simple tests .pdf
aquastore223
 
The van t Hoff factor i (named after J. H. van t Hoff) is a meas.pdf
The van t Hoff factor i (named after J. H. van t Hoff) is a meas.pdfThe van t Hoff factor i (named after J. H. van t Hoff) is a meas.pdf
The van t Hoff factor i (named after J. H. van t Hoff) is a meas.pdf
aquastore223
 
Polar Bonds and Molecular Shape A polar molecule.pdf
                     Polar Bonds and Molecular Shape  A polar molecule.pdf                     Polar Bonds and Molecular Shape  A polar molecule.pdf
Polar Bonds and Molecular Shape A polar molecule.pdf
aquastore223
 
The good functioning of an economy depends on the proper functioning.pdf
The good functioning of an economy depends on the proper functioning.pdfThe good functioning of an economy depends on the proper functioning.pdf
The good functioning of an economy depends on the proper functioning.pdf
aquastore223
 
Stegosaurus dinosaur belonged to the late jurassic period i.e Kimmer.pdf
Stegosaurus dinosaur belonged to the late jurassic period i.e Kimmer.pdfStegosaurus dinosaur belonged to the late jurassic period i.e Kimmer.pdf
Stegosaurus dinosaur belonged to the late jurassic period i.e Kimmer.pdf
aquastore223
 

More from aquastore223 (20)

1. How new modern materials prompted changes in architecture in the .pdf
1. How new modern materials prompted changes in architecture in the .pdf1. How new modern materials prompted changes in architecture in the .pdf
1. How new modern materials prompted changes in architecture in the .pdf
 
c++ code for a Median of Integer Stream from Text File program#.pdf
 c++ code for a Median of Integer Stream from Text File program#.pdf c++ code for a Median of Integer Stream from Text File program#.pdf
c++ code for a Median of Integer Stream from Text File program#.pdf
 
1) cobalt iodide has an intense color, thus this colorless salt cann.pdf
1) cobalt iodide has an intense color, thus this colorless salt cann.pdf1) cobalt iodide has an intense color, thus this colorless salt cann.pdf
1) cobalt iodide has an intense color, thus this colorless salt cann.pdf
 
the hybridisation is sp2 since the electron cloud.pdf
                     the hybridisation is sp2 since the electron cloud.pdf                     the hybridisation is sp2 since the electron cloud.pdf
the hybridisation is sp2 since the electron cloud.pdf
 
Sodium hydroxide, also known as lye and caustic s.pdf
                     Sodium hydroxide, also known as lye and caustic s.pdf                     Sodium hydroxide, also known as lye and caustic s.pdf
Sodium hydroxide, also known as lye and caustic s.pdf
 
Hydrocrbon is the organic compound which containing only the atoms .pdf
   Hydrocrbon is the organic compound which containing only the atoms .pdf   Hydrocrbon is the organic compound which containing only the atoms .pdf
Hydrocrbon is the organic compound which containing only the atoms .pdf
 
No. In order for a substance to conduct electrici.pdf
                     No. In order for a substance to conduct electrici.pdf                     No. In order for a substance to conduct electrici.pdf
No. In order for a substance to conduct electrici.pdf
 
HCHO OS for H is +1, O is -2 there are two Hs o.pdf
                     HCHO OS for H is +1, O is -2 there are two Hs o.pdf                     HCHO OS for H is +1, O is -2 there are two Hs o.pdf
HCHO OS for H is +1, O is -2 there are two Hs o.pdf
 
The molecular orbital (MO) theory is a way of loo.pdf
                     The molecular orbital (MO) theory is a way of loo.pdf                     The molecular orbital (MO) theory is a way of loo.pdf
The molecular orbital (MO) theory is a way of loo.pdf
 
The electrons reach or give off a certain amount of energy and diffe.pdf
  The electrons reach or give off a certain amount of energy and diffe.pdf  The electrons reach or give off a certain amount of energy and diffe.pdf
The electrons reach or give off a certain amount of energy and diffe.pdf
 
Weak London disperision and dipole- dipoleModerate Hydrogen bond.pdf
Weak London disperision and dipole- dipoleModerate Hydrogen bond.pdfWeak London disperision and dipole- dipoleModerate Hydrogen bond.pdf
Weak London disperision and dipole- dipoleModerate Hydrogen bond.pdf
 
var min =0; var max=10; var tab = {}; var name; var score;.pdf
var min =0; var max=10; var tab = {}; var name; var score;.pdfvar min =0; var max=10; var tab = {}; var name; var score;.pdf
var min =0; var max=10; var tab = {}; var name; var score;.pdf
 
Unfortunately several cancers are not predictable with simple tests .pdf
Unfortunately several cancers are not predictable with simple tests .pdfUnfortunately several cancers are not predictable with simple tests .pdf
Unfortunately several cancers are not predictable with simple tests .pdf
 
The van t Hoff factor i (named after J. H. van t Hoff) is a meas.pdf
The van t Hoff factor i (named after J. H. van t Hoff) is a meas.pdfThe van t Hoff factor i (named after J. H. van t Hoff) is a meas.pdf
The van t Hoff factor i (named after J. H. van t Hoff) is a meas.pdf
 
Polar Bonds and Molecular Shape A polar molecule.pdf
                     Polar Bonds and Molecular Shape  A polar molecule.pdf                     Polar Bonds and Molecular Shape  A polar molecule.pdf
Polar Bonds and Molecular Shape A polar molecule.pdf
 
The good functioning of an economy depends on the proper functioning.pdf
The good functioning of an economy depends on the proper functioning.pdfThe good functioning of an economy depends on the proper functioning.pdf
The good functioning of an economy depends on the proper functioning.pdf
 
The answer is Yes, it is a reduction-oxidation reaction2 HNO2 + 2.pdf
The answer is Yes, it is a reduction-oxidation reaction2 HNO2 + 2.pdfThe answer is Yes, it is a reduction-oxidation reaction2 HNO2 + 2.pdf
The answer is Yes, it is a reduction-oxidation reaction2 HNO2 + 2.pdf
 
Stegosaurus dinosaur belonged to the late jurassic period i.e Kimmer.pdf
Stegosaurus dinosaur belonged to the late jurassic period i.e Kimmer.pdfStegosaurus dinosaur belonged to the late jurassic period i.e Kimmer.pdf
Stegosaurus dinosaur belonged to the late jurassic period i.e Kimmer.pdf
 
The answer is d- the hydrogen bonds in iceThe high heat of fusion.pdf
The answer is d- the hydrogen bonds in iceThe high heat of fusion.pdfThe answer is d- the hydrogen bonds in iceThe high heat of fusion.pdf
The answer is d- the hydrogen bonds in iceThe high heat of fusion.pdf
 
SolutionOption (a) will qualify as a database as dictionary is a .pdf
SolutionOption (a) will qualify as a database as dictionary is a .pdfSolutionOption (a) will qualify as a database as dictionary is a .pdf
SolutionOption (a) will qualify as a database as dictionary is a .pdf
 

Recently uploaded

The basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptxThe basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptx
heathfieldcps1
 
Transparency, Recognition and the role of eSealing - Ildiko Mazar and Koen No...
Transparency, Recognition and the role of eSealing - Ildiko Mazar and Koen No...Transparency, Recognition and the role of eSealing - Ildiko Mazar and Koen No...
Transparency, Recognition and the role of eSealing - Ildiko Mazar and Koen No...
EADTU
 

Recently uploaded (20)

dusjagr & nano talk on open tools for agriculture research and learning
dusjagr & nano talk on open tools for agriculture research and learningdusjagr & nano talk on open tools for agriculture research and learning
dusjagr & nano talk on open tools for agriculture research and learning
 
Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...
Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...
Beyond_Borders_Understanding_Anime_and_Manga_Fandom_A_Comprehensive_Audience_...
 
On_Translating_a_Tamil_Poem_by_A_K_Ramanujan.pptx
On_Translating_a_Tamil_Poem_by_A_K_Ramanujan.pptxOn_Translating_a_Tamil_Poem_by_A_K_Ramanujan.pptx
On_Translating_a_Tamil_Poem_by_A_K_Ramanujan.pptx
 
HMCS Vancouver Pre-Deployment Brief - May 2024 (Web Version).pptx
HMCS Vancouver Pre-Deployment Brief - May 2024 (Web Version).pptxHMCS Vancouver Pre-Deployment Brief - May 2024 (Web Version).pptx
HMCS Vancouver Pre-Deployment Brief - May 2024 (Web Version).pptx
 
21st_Century_Skills_Framework_Final_Presentation_2.pptx
21st_Century_Skills_Framework_Final_Presentation_2.pptx21st_Century_Skills_Framework_Final_Presentation_2.pptx
21st_Century_Skills_Framework_Final_Presentation_2.pptx
 
The basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptxThe basics of sentences session 3pptx.pptx
The basics of sentences session 3pptx.pptx
 
Transparency, Recognition and the role of eSealing - Ildiko Mazar and Koen No...
Transparency, Recognition and the role of eSealing - Ildiko Mazar and Koen No...Transparency, Recognition and the role of eSealing - Ildiko Mazar and Koen No...
Transparency, Recognition and the role of eSealing - Ildiko Mazar and Koen No...
 
Play hard learn harder: The Serious Business of Play
Play hard learn harder:  The Serious Business of PlayPlay hard learn harder:  The Serious Business of Play
Play hard learn harder: The Serious Business of Play
 
COMMUNICATING NEGATIVE NEWS - APPROACHES .pptx
COMMUNICATING NEGATIVE NEWS - APPROACHES .pptxCOMMUNICATING NEGATIVE NEWS - APPROACHES .pptx
COMMUNICATING NEGATIVE NEWS - APPROACHES .pptx
 
Accessible Digital Futures project (20/03/2024)
Accessible Digital Futures project (20/03/2024)Accessible Digital Futures project (20/03/2024)
Accessible Digital Futures project (20/03/2024)
 
PANDITA RAMABAI- Indian political thought GENDER.pptx
PANDITA RAMABAI- Indian political thought GENDER.pptxPANDITA RAMABAI- Indian political thought GENDER.pptx
PANDITA RAMABAI- Indian political thought GENDER.pptx
 
Tatlong Kwento ni Lola basyang-1.pdf arts
Tatlong Kwento ni Lola basyang-1.pdf artsTatlong Kwento ni Lola basyang-1.pdf arts
Tatlong Kwento ni Lola basyang-1.pdf arts
 
How to setup Pycharm environment for Odoo 17.pptx
How to setup Pycharm environment for Odoo 17.pptxHow to setup Pycharm environment for Odoo 17.pptx
How to setup Pycharm environment for Odoo 17.pptx
 
REMIFENTANIL: An Ultra short acting opioid.pptx
REMIFENTANIL: An Ultra short acting opioid.pptxREMIFENTANIL: An Ultra short acting opioid.pptx
REMIFENTANIL: An Ultra short acting opioid.pptx
 
How to Add a Tool Tip to a Field in Odoo 17
How to Add a Tool Tip to a Field in Odoo 17How to Add a Tool Tip to a Field in Odoo 17
How to Add a Tool Tip to a Field in Odoo 17
 
Interdisciplinary_Insights_Data_Collection_Methods.pptx
Interdisciplinary_Insights_Data_Collection_Methods.pptxInterdisciplinary_Insights_Data_Collection_Methods.pptx
Interdisciplinary_Insights_Data_Collection_Methods.pptx
 
OS-operating systems- ch05 (CPU Scheduling) ...
OS-operating systems- ch05 (CPU Scheduling) ...OS-operating systems- ch05 (CPU Scheduling) ...
OS-operating systems- ch05 (CPU Scheduling) ...
 
FICTIONAL SALESMAN/SALESMAN SNSW 2024.pdf
FICTIONAL SALESMAN/SALESMAN SNSW 2024.pdfFICTIONAL SALESMAN/SALESMAN SNSW 2024.pdf
FICTIONAL SALESMAN/SALESMAN SNSW 2024.pdf
 
Details on CBSE Compartment Exam.pptx1111
Details on CBSE Compartment Exam.pptx1111Details on CBSE Compartment Exam.pptx1111
Details on CBSE Compartment Exam.pptx1111
 
OSCM Unit 2_Operations Processes & Systems
OSCM Unit 2_Operations Processes & SystemsOSCM Unit 2_Operations Processes & Systems
OSCM Unit 2_Operations Processes & Systems
 

A bacterial pathogen is usually defined as any bacterium that has th.pdf

  • 1. A bacterial pathogen is usually defined as any bacterium that has the capacity to cause disease. Its ability to cause disease is called pathogenicity. Virulence provides a quantitative measure of the pathogenicity or the likelihood of causing disease. Virulence factors refer to the properties (i.e., gene products) that enable a microorganism to establish itself on or within a host of a particular species and enhance its potential to cause disease. Virulence factors include bacterial toxins, cell surface proteins that mediate bacterial attachment, cell surface carbohydrates and proteins that protect a bacterium, and hydrolytic enzymes that may contribute to the pathogenicity of the bacterium. Virulence factors help bacteria to (3) evade host defenses. TYPES OF VIRULENT FACTORS and THEIR ROLES: The following are types of virulence factors: Adherence Factors: Many pathogenic bacteria colonize mucosal sites by using pili (fimbriae) to adhere to cells. Invasion Factors: Surface components that allow the bacterium to invade host cells can be encoded on plasmids, but more often are on the chromosome. Capsules: Many bacteria are surrounded by capsules that protect them from opsonization and phagocytosis. Endotoxins: The lipopolysaccharide endotoxins on Gram-negative bacteria cause fever, changes in blood pressure, inflammation, lethal shock, and many other toxic events. Exotoxins: Exotoxins include several types of protein toxins and enzymes produced and/or secreted from pathogenic bacteria. Major categories include cytotoxins, neurotoxins, and enterotoxins. Siderophores: Siderophores are iron-binding factors that allow some bacteria to compete with the host for iron, which is bound to hemoglobin, transferrin, and lactoferrin. Solution A bacterial pathogen is usually defined as any bacterium that has the capacity to cause disease. Its ability to cause disease is called pathogenicity. Virulence provides a quantitative measure of the pathogenicity or the likelihood of causing disease.
  • 2. Virulence factors refer to the properties (i.e., gene products) that enable a microorganism to establish itself on or within a host of a particular species and enhance its potential to cause disease. Virulence factors include bacterial toxins, cell surface proteins that mediate bacterial attachment, cell surface carbohydrates and proteins that protect a bacterium, and hydrolytic enzymes that may contribute to the pathogenicity of the bacterium. Virulence factors help bacteria to (3) evade host defenses. TYPES OF VIRULENT FACTORS and THEIR ROLES: The following are types of virulence factors: Adherence Factors: Many pathogenic bacteria colonize mucosal sites by using pili (fimbriae) to adhere to cells. Invasion Factors: Surface components that allow the bacterium to invade host cells can be encoded on plasmids, but more often are on the chromosome. Capsules: Many bacteria are surrounded by capsules that protect them from opsonization and phagocytosis. Endotoxins: The lipopolysaccharide endotoxins on Gram-negative bacteria cause fever, changes in blood pressure, inflammation, lethal shock, and many other toxic events. Exotoxins: Exotoxins include several types of protein toxins and enzymes produced and/or secreted from pathogenic bacteria. Major categories include cytotoxins, neurotoxins, and enterotoxins. Siderophores: Siderophores are iron-binding factors that allow some bacteria to compete with the host for iron, which is bound to hemoglobin, transferrin, and lactoferrin.