The internal architecture of the Intel 8085 microprocessor consists of 6 general purpose registers (B, C, D, E, H, L) that can store 8-bit data during program execution. It also includes an accumulator register (A) for performing arithmetic and logical operations, a program counter (PC) for sequencing instruction execution, and a stack pointer (SP) for temporary data storage. Other components are an instruction register and decoder for fetching and decoding instructions, a flag register for testing data conditions, and control logic for synchronizing operations and communication with peripherals.
It is a central processing unit etched on a single chip.A single integrated circuit has all the functional components of a cpu namely ALU,CONTROL UNIT & REGISTERS
It is a central processing unit etched on a single chip.A single integrated circuit has all the functional components of a cpu namely ALU,CONTROL UNIT & REGISTERS
A microprocessor is an electronic component that is used by a computer to do its work. It is a central processing unit on a single integrated circuit chip containing millions of very small components including transistors, resistors, and diodes that work together. Some microprocessors in the 20th century required several chips. Microprocessors help to do everything from controlling elevators to searching the Web. Everything a computer does is described by instructions of computer programs, and microprocessors carry out these instructions many millions of times a second. [1]
Microprocessors were invented in the 1970s for use in embedded systems. The majority are still used that way, in such things as mobile phones, cars, military weapons, and home appliances. Some microprocessors are microcontrollers, so small and inexpensive that they are used to control very simple products like flashlights and greeting cards that play music when you open them. A few especially powerful microprocessors are used in personal computers.
A microprocessor is an electronic component that is used by a computer to do its work. It is a central processing unit on a single integrated circuit chip containing millions of very small components including transistors, resistors, and diodes that work together. Some microprocessors in the 20th century required several chips. Microprocessors help to do everything from controlling elevators to searching the Web. Everything a computer does is described by instructions of computer programs, and microprocessors carry out these instructions many millions of times a second. [1]
Microprocessors were invented in the 1970s for use in embedded systems. The majority are still used that way, in such things as mobile phones, cars, military weapons, and home appliances. Some microprocessors are microcontrollers, so small and inexpensive that they are used to control very simple products like flashlights and greeting cards that play music when you open them. A few especially powerful microprocessors are used in personal computers.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
A microprocessor is an electronic component that is used by a computer to do its work. It is a central processing unit on a single integrated circuit chip containing millions of very small components including transistors, resistors, and diodes that work together. Some microprocessors in the 20th century required several chips. Microprocessors help to do everything from controlling elevators to searching the Web. Everything a computer does is described by instructions of computer programs, and microprocessors carry out these instructions many millions of times a second. [1]
Microprocessors were invented in the 1970s for use in embedded systems. The majority are still used that way, in such things as mobile phones, cars, military weapons, and home appliances. Some microprocessors are microcontrollers, so small and inexpensive that they are used to control very simple products like flashlights and greeting cards that play music when you open them. A few especially powerful microprocessors are used in personal computers.
A microprocessor is an electronic component that is used by a computer to do its work. It is a central processing unit on a single integrated circuit chip containing millions of very small components including transistors, resistors, and diodes that work together. Some microprocessors in the 20th century required several chips. Microprocessors help to do everything from controlling elevators to searching the Web. Everything a computer does is described by instructions of computer programs, and microprocessors carry out these instructions many millions of times a second. [1]
Microprocessors were invented in the 1970s for use in embedded systems. The majority are still used that way, in such things as mobile phones, cars, military weapons, and home appliances. Some microprocessors are microcontrollers, so small and inexpensive that they are used to control very simple products like flashlights and greeting cards that play music when you open them. A few especially powerful microprocessors are used in personal computers.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Observation of Io’s Resurfacing via Plume Deposition Using Ground-based Adapt...Sérgio Sacani
Since volcanic activity was first discovered on Io from Voyager images in 1979, changes
on Io’s surface have been monitored from both spacecraft and ground-based telescopes.
Here, we present the highest spatial resolution images of Io ever obtained from a groundbased telescope. These images, acquired by the SHARK-VIS instrument on the Large
Binocular Telescope, show evidence of a major resurfacing event on Io’s trailing hemisphere. When compared to the most recent spacecraft images, the SHARK-VIS images
show that a plume deposit from a powerful eruption at Pillan Patera has covered part
of the long-lived Pele plume deposit. Although this type of resurfacing event may be common on Io, few have been detected due to the rarity of spacecraft visits and the previously low spatial resolution available from Earth-based telescopes. The SHARK-VIS instrument ushers in a new era of high resolution imaging of Io’s surface using adaptive
optics at visible wavelengths.
4. The internal architecture of the 8085 microprocessor
determines how and what operations can be performed with the data
operations are,
Store 8-bit data.
Perform arithmetic and logical operations.
Test for conditions.
Sequence the execution of instructions.
Store data temporarily in read write memory called stack.
5. The 8085 has 6 general purpose registers to store 8-bit data during
program execution.
These 6 registers are identified as B, C, D, E, H and L.
They can be combined as register pairs BC, DE and HL to perform
some 16-bit operations.
These registers are programmable. It can use to load or transfer data
from the registers by using instructions.
Registers
6. The accumulator (A) is an 8-bit register that is part of ALU.
It is used to store 8-bit data and to perform ALU operations.
The result of an operation is stored in Accumulator.
The Accumulator is identified as register A.
The data on which operations is to be performed is operand. One
of the operands must be Accumulator.
Accumulator
7. This 16-bit register deals with sequencing the execution of instructions.
This register is a memory pointer. Memory locations have 16-bit address.
The microprocessor uses this register to sequence the execution of the
instructions.
The function of the program counter is to point to the memory address
from which the next byte is to be fetched.
When a byte is being fetched, the program counter is automatically
incremented by one to point to the next memory location.
Program Counter (PC)
8. The stack pointer is also a 16-bit register, used as a memory
pointer.
It points to a memory location in R/W memory, called stack.
The beginning of the stack is defined by loading 16- bit address in
the stack pointer.
Stack Pointer (SP)
9. This unit synchronizes all the microprocessor operations with
the clock and generates the control signal necessary for
communication between the microprocessor and peripherals.
The control signals are similar to a sync pulse in an
oscilloscope. The 𝑅𝐷 and 𝑊𝑅 signals are sync pulses
indicating the availability of data on the data bus.
Timing and control unit
10. The instruction register and decoder are part of the ALU.
When an instruction is fetched from the memory it is loaded in to
the instruction register.
The decoder decodes the instruction and establishes the sequence
of events to follow.
The instruction register is not programmable and cannot be
accessed by any instruction.
Instruction register and Decoder
11. There are two additional registers called temporary registers W and
Z, which are included in the register array along with
programmable registers namely B, C, D, E, H, L, SP and PC.
These registers are used to hold 8-bit data during the execution of
instructions. However, they are used internally by microprocessor,
they are available to the program.
Register Array
12. This unit is used to select a register out of all the available registers.
This unit behaves as Multiplexer (MUX) when data going from the
register to the internal data bus.
It behaves as Demultiplexer(DEMUX) when data is coming to a
register from the internal data bus of the processor.
The register select will behave as the function of selection lines at
the Mux / Demux.
MUX / DEMUX unit
13. This is an 8-bit unidirectional buffer.
It is used to drive external high order address bus (A15 – A8).
It is also used to tri-state the high order address bus under certain
conditions such as reset, hold, halt and when address lines are not
in use.
Address Buffer
14. This is an 8-bit bi-directional buffer.
It is used to drive multiplexed address/data bus. i.e., low order
address bus (A7-A0) and data bus (D7-D0).
It is also to tri-state the multiplexed address/data bus under certain
conditions such as reset, hold, halt and when the bus is not in use.
Address / Data Buffer
15. This 16-bit register is used to increment or decrement
the contents of program counter or stack pointer as part
of execution of instructions related to them.
Incrementor/Decremented address latch
16. The ALU includes five flip-flops, which are set (or) reset after an
operation according to data condition of the result in the
accumulator and other registers.
They are called Zero (Z), Carry (CY), Sign (S), Parity (P) and
Auxiliary Carry (AC) flags.
Their bit positions in the flag register are shown in Fig. The
microprocessor uses these flags to test data conditions.
Flag register