8. There estimated there exist 105MHC molecules on cell surfaces of each antigen-presenting cell under normal situations. Majority of the peptidebinding cleft of MHC on cell surfaces are found to be A. No peptides B. Peptides from self proteins C. peptides from pathogens D. peptides from tumors E. peptides from allergens 9. Class I peptides are bound only with MHC I but not MHC II in because in which MHC II is covered by A. Golgi complex, li B. ER, Invariant chain (li) C. ER, HLA- DM D. Golgi, HLA-DM E. Endosome, Invariant chain (Ii) 10. Place the following stages of B-cell development in the correct chronological order. DABCE A. pro-B cell B. pre-B cell C. Immature B cell D. Stem cell E. Mature B cell11. Which of the following statements regarding the V (variable) region of immunoglobulin is NOT true: A. Determines the clonality B. Determines the class of Igs C. Formed by somatic recombination among V,D and J gene segments during B lymphocyte development D. Mediates the binding with antigen (epitope) 12. In your body all the cells listed below will have the chromosome configuration of IgH gene locus at chromosome 14 as drawn above in which none is recombined, EXCEPT: A. neuron B. Langerhans cell C. hepatocyte D. Stem cell E. Mature B lymphocytes 13. Human papillomavirus (HPV) infection of the genital tract is common in young sexually active individuals. In the case of HPV infection, which is CORRECT: A. a naive CD8 T cell can be activated by HPV- infected epithelial cells in the reproductive tract B. the activation of CTL by HPV- infected epithelial cell needs costimulation. C. a naive CD8 T cell is activated by dendritic cells in the reproductive tract..

1. 8. There estimated there exist 105MHC molecules on cell surfaces of each antigen-presenting cell
under normal situations. Majority of the peptidebinding cleft of MHC on cell surfaces are found to
be A. No peptides B. Peptides from self proteins C. peptides from pathogens D. peptides from
tumors E. peptides from allergens 9. Class I peptides are bound only with MHC I but not MHC II in
because in which MHC II is covered by A. Golgi complex, li B. ER, Invariant chain (li) C. ER, HLA-
DM D. Golgi, HLA-DM E. Endosome, Invariant chain (Ii) 10. Place the following stages of B-cell
development in the correct chronological order. DABCE A. pro-B cell B. pre-B cell C. Immature B
cell D. Stem cell E. Mature B cell11. Which of the following statements regarding the V (variable)
region of immunoglobulin is NOT true: A. Determines the clonality B. Determines the class of Igs
C. Formed by somatic recombination among V,D and J gene segments during B lymphocyte
development D. Mediates the binding with antigen (epitope) 12. In your body all the cells listed
below will have the chromosome configuration of IgH gene locus at chromosome 14 as drawn
above in which none is recombined, EXCEPT: A. neuron B. Langerhans cell C. hepatocyte D.
Stem cell E. Mature B lymphocytes 13. Human papillomavirus (HPV) infection of the genital tract is
common in young sexually active individuals. In the case of HPV infection, which is CORRECT: A.
a naive CD8 T cell can be activated by HPV- infected epithelial cells in the reproductive tract B.
the activation of CTL by HPV- infected epithelial cell needs costimulation. C. a naive CD8 T cell is
activated by dendritic cells in the reproductive tract.