The document summarizes information about Plasmodium spp, the parasite that causes malaria. It is transmitted through the bites of infected female Anopheles mosquitoes. There are four main types of Plasmodium, with P. falciparum causing 90% of cases and being the most severe. Malaria symptoms include fever, chills, sweating, and resting. Complications from malaria can include anemia, renal failure, hypoglycemia, spleen enlargement, jaundice, and cerebral malaria. Treatment depends on the severity and type of malaria, with drugs like primaquine, chloroquine, quinine, and artemether-lumefantrine being used.
Unit-IV; Professional Sales Representative (PSR).pptx
7-plasmodium malaria_3.docx
1. Summary of Medical parasitology Dr/Faiz AL-Khawlani
Plasmodium spp ( malaria )
Parasite Female Anopheles mosquitoes
Types : 1-P.falciparum "90%" 2-P.vivax " 10% "
3-P.ovalae " no found" 4-P.malarae " rare found "
Disease name : Malaria
Infective stage : Sporozoites
Host : -Definitive host : mosquitoes
-Intermediate host :Man
Distribution : World wide cases more than millions disease
M.O.Transmission:
1- by the bite of female Anopheles mosquitoes
2-By blood transfusion
3-by placenta transfusion in pregnancy
4-using the partaken syringes
Clinical symptoms :
1-Malaria fever
2-Chills
3-Sweating
4-Resting
Complications :
1-Hemolytic anemia
2-Acute renal failure p. falciparum
3-Hypoglycemia
4-Spleenomegaly
5-Jaundice
6-Cerebral malaria coma
Treatment:
Drugs Uses Dose
Primaquine Choice drug for hypnozoite
Chloroquine
-First line in uncomplicated malaria
-Used therapy and prophylaxis due to long half life
Quinine +glucose -First line in acute & sever malaria
-Safe for pregnancy
Qoartem
(Artemether+lume-fantrine )
For uncomplicated malaria
6 doses over 3d
(4tabs/dose at 0, 8, 24,36, 48 and 60 hrs)